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Two BCMA\u2010directed CAR T\u2010cell products \u2014 idecabtagene vicleucel (ide\u2010cel) and ciltacabtagene autoleucel (cilta\u2010cel) \u2014 have received US Food and Drug Administration (FDA) approval for patients with relapsed\/refractory MM who underwent four or more prior lines of therapy (including an immunomodulatory agent, a proteasome inhibitor, and an anti\u2010CD38 monoclonal antibody). Despite producing unprecedented response rates in an otherwise difficult to treat patient population, CAR T\u2010cell therapies are commonly associated with immune\u2010related adverse events (e.g., cytokine release syndrome and neurotoxicity), cytopenias, and infections. Moreover, many patients continue to exhibit relapse post\u2010treatment, with resistance mechanisms yet to be fully understood. 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