{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T12:30:25Z","timestamp":1787056225573,"version":"build-2736575974"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T00:00:00Z","timestamp":1451865600000},"content-version":"vor","delay-in-days":17535,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pharma and Therapeutics"],"published-print":{"date-parts":[[1968,1]]},"abstract":"<jats:p>Urinary excretion for 10 hours after a small oral dose of several halogenated 8\u2010hydroxyquinolines was spectrophotometrically determined in a series of normal human sub;ects. No free forms of drug were found. The determinations were made on the glucuronic acid con;ugates, and the excretions in per cent of the dose were: di\u2010iodo\u20108\u2010hydroxyquinoline, 4.6 per cent; di\u2010bromo\u20108\u2010hydroxyquinoline, 10.2 per cent; chloro\u2010iodo\u20108\u2010hydroxyquinoline, 12.6 per cent; di\u2010chloro\u2010methyl\u20108\u2010hydroxyquinoline, 34.9 per cent. Three normal children and two patients (suspected of having 8\u2010hydroxyquinoline toxicity) who received chloro\u2010iodo\u20108\u2010hydroxyquinoline had a similar excretion. Human absorption and ocular toxicity are discussed.<\/jats:p>","DOI":"10.1002\/cpt19689167","type":"journal-article","created":{"date-parts":[[2016,1,5]],"date-time":"2016-01-05T00:45:53Z","timestamp":1451954753000},"page":"67-70","source":"Crossref","is-referenced-by-count":50,"title":["Absorption of intestinal antiseptics derived from 8\u2010hydroxyquinolines"],"prefix":"10.1111","volume":"9","author":[{"given":"Lennart","family":"Berggren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olle","family":"Hansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,4]]},"container-title":["Clinical Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcpt19689167","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcpt19689167","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cpt19689167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T13:33:29Z","timestamp":1699364009000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/10.1002\/cpt19689167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1968,1]]}},"alternative-id":["10.1002\/cpt19689167"],"URL":"https:\/\/doi.org\/10.1002\/cpt19689167","archive":["Portico"],"relation":{},"ISSN":["0009-9236","1532-6535"],"issn-type":[{"value":"0009-9236","type":"print"},{"value":"1532-6535","type":"electronic"}],"subject":[],"published":{"date-parts":[[1968,1]]}}}