{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:26:08Z","timestamp":1790666768754,"version":"4.1.0"},"reference-count":0,"publisher":"Wiley","issue":"5part1","license":[{"start":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T00:00:00Z","timestamp":1451865600000},"content-version":"vor","delay-in-days":15039,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pharma and Therapeutics"],"published-print":{"date-parts":[[1974,11]]},"abstract":"<jats:p>Factors influencing drug utilization were studied in 7,575 hospitalized patients on a 65 bed general medical service during a 3\u00bd year period. Nine index drug groups, including analgesic, antacid, antiarrhythmic, antimicrobic, anticoagulant, antihypertensive, anti\u2010inflammatory, diuretic, and sedative\u2010tranqUilizer drugs were used to evaluate drug utilization. The average number of drugs received by each patient was 8.04, and the average patient drug exposure for the 9 index drug groups was 4.75. The average patient drug exposure to index therapeutic drug groups was found to be significantly higher during the February\u2010March and April\u2010May periods than during the August\u2010September and December\u2010January periods of the study. Factors found to have a significant influence on drug use included the formulary system and changes in the availability of drugs. Distribution of a drug letter published by the Pharmacy and Therapeutics Committee did not appear to affect drug prescribing.<\/jats:p>","DOI":"10.1002\/cpt1974165part1834","type":"journal-article","created":{"date-parts":[[2016,1,5]],"date-time":"2016-01-05T01:36:53Z","timestamp":1451957813000},"page":"834-845","source":"Crossref","is-referenced-by-count":23,"title":["Drug use in the hospital: Evaluation of determinants"],"prefix":"10.1111","volume":"16","author":[{"given":"Franklin E.","family":"May","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald B.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leighton E.","family":"Cluff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,4]]},"container-title":["Clinical Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcpt1974165part1834","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcpt1974165part1834","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cpt1974165part1834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T13:33:28Z","timestamp":1699364008000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/10.1002\/cpt1974165part1834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,11]]},"references-count":0,"journal-issue":{"issue":"5part1","published-print":{"date-parts":[[1974,11]]}},"alternative-id":["10.1002\/cpt1974165part1834"],"URL":"https:\/\/doi.org\/10.1002\/cpt1974165part1834","archive":["Portico"],"relation":{},"ISSN":["0009-9236","1532-6535"],"issn-type":[{"value":"0009-9236","type":"print"},{"value":"1532-6535","type":"electronic"}],"subject":[],"published":{"date-parts":[[1974,11]]}}}