{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T00:19:27Z","timestamp":1699402767291},"reference-count":0,"publisher":"Wiley","issue":"5part2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"vor","delay-in-days":15433,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pharma and Therapeutics"],"published-print":{"date-parts":[[1974,11]]},"abstract":"<jats:p>The fortuitous observations of Richard Gubner, an internist, that psoriasis responded to systemic treatment with the antimetabolic agent aminopterin stimulated an interest in the use of anti proliferative drugs for skin diseases.<jats:sup>10<\/jats:sup> The subsequent reports of Rees, Bennett, and Bostick,<jats:sup>22<\/jats:sup> VanScott, Auerbach, and Weinstein,<jats:sup>27<\/jats:sup> Callaway, McAfee, and Finlayson,<jats:sup>5<\/jats:sup> and others corroborated these findings using aminopterin and the analogue methotrexate (MTX). Other investigators extended these observations on antimetabolic agents in psoriasis to include such antiproliferative drugs as triacetyl\u20106\u2010azauridine<jats:sup>26<\/jats:sup> and hydroxyurea.<jats:sup>12<\/jats:sup><\/jats:p>","DOI":"10.1002\/cpt1974165part2934","type":"journal-article","created":{"date-parts":[[2016,1,5]],"date-time":"2016-01-05T16:27:34Z","timestamp":1452011254000},"page":"934-939","source":"Crossref","is-referenced-by-count":1,"title":["Cutaneous uses of the antiproliferative drugs"],"prefix":"10.1111","volume":"16","author":[{"given":"Charles J.","family":"McDonald","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2]]},"container-title":["Clinical Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcpt1974165part2934","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcpt1974165part2934","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cpt1974165part2934","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T13:32:23Z","timestamp":1699363943000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/10.1002\/cpt1974165part2934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,11]]},"references-count":0,"journal-issue":{"issue":"5part2","published-print":{"date-parts":[[1974,11]]}},"alternative-id":["10.1002\/cpt1974165part2934"],"URL":"https:\/\/doi.org\/10.1002\/cpt1974165part2934","archive":["Portico"],"relation":{},"ISSN":["0009-9236","1532-6535"],"issn-type":[{"value":"0009-9236","type":"print"},{"value":"1532-6535","type":"electronic"}],"subject":[],"published":{"date-parts":[[1974,11]]}}}