{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T11:53:12Z","timestamp":1781610792171,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32322042"],"award-info":[{"award-number":["32322042"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271359"],"award-info":[{"award-number":["32271359"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["20DZ2220400"],"award-info":[{"award-number":["20DZ2220400"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Protocols"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Magnetic resonance elastography (MRE) enables non\u2010invasive assessment of the mechanical properties of brain tissue, which is crucial for diagnosing neurodegenerative diseases and understanding brain development. This technique relies on inducing controlled harmonic deformation in brain tissue and detecting the resulting motion via motion\u2010sensitive magnetic resonance imaging (MRI) sequences. Electromagnetic actuators, which leverage the static magnetic field of MRI scanners and Lorentz law to generate rotary vibration, offer a cost\u2010effective solution for brain MRE. However, their application in brain MRE requires addressing MRI safety challenges from metallic components and coil positioning inflexibility. Here, we present a comprehensive protocol for designing, constructing, and implementing an electromagnetic actuator tailored for brain MRE experiments. We detail key considerations including design of an actuator capable of reducing electromagnetic interference and vibration stimulation, construction of a controller for the actuator, design schematic of an MRE sequence, and methods for obtaining final mechanical results of MRE. This protocol aims to provide a practical guide for research laboratories seeking to develop MRE systems, facilitating accurate and reproducible assessment of brain mechanical properties for both basic research and clinical translation. \u00a9 2026 Wiley Periodicals LLC.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Basic Protocol<\/jats:bold>\n                    : Design, construction, and implementation of an electromagnetic MRE actuator for brain MRE\n                  <\/jats:p>","DOI":"10.1002\/cpz1.70364","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T09:45:30Z","timestamp":1778579130000},"source":"Crossref","is-referenced-by-count":0,"title":["Brain Magnetic Resonance Elastography Experiments With an Electromagnetic Actuator"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7366-7023","authenticated-orcid":false,"given":"Suhao","family":"Qiu","sequence":"first","affiliation":[{"name":"Shanghai Key Laboratory of Flexible Medical Robotics, Tongren Hospital, Institute of Medical Robotics Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1902-3408","authenticated-orcid":false,"given":"Yuan","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Institute of Medical Robotics, National Engineering Research Center of Advanced Magnetic Resonance Technologies for Diagnosis and Therapy (NERC\u2010AMRT) Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang\u2010Zhong","family":"Yang","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of Flexible Medical Robotics, Tongren Hospital, Institute of Medical Robotics Shanghai Jiao Tong University  Shanghai China"},{"name":"School of Biomedical Engineering, Institute of Medical Robotics Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.16.17455"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.3388"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24674"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/61\/24\/R401"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092582"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2013.09.006"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1109\/tmi.2023.3261346"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28627"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.21006"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/56\/13\/N02"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2017.10.008"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22707"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/57\/8\/2329"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28855"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2015.06.001"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.4592"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/RMR.0000000000000178"}],"container-title":["Current 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