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Currently there is no cure for hearing loss. Treatment options are limited to hearing aids for mild and moderate cases, and cochlear implants for severe and profound hearing loss. Here we provide a literature overview of the environmental and genetic causes of congenital hearing loss, common animal models and methods used for hearing research, as well as recent advances towards developing therapies to treat congenital deafness. \u00a9 2021 The Authors.<\/jats:p>","DOI":"10.1002\/cpz1.76","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T13:07:00Z","timestamp":1617023220000},"source":"Crossref","is-referenced-by-count":27,"title":["Congenital Deafness and Recent Advances Towards Restoring Hearing Loss"],"prefix":"10.1002","volume":"1","author":[{"given":"Justine M.","family":"Renauld","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery Case Western Reserve University School of Medicine  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin L.","family":"Basch","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head &amp; Neck Surgery Case Western Reserve University School of Medicine  Cleveland Ohio"},{"name":"Department of Genetics and Genome Sciences Case Western Reserve School of Medicine  Cleveland Ohio"},{"name":"Department of Biology Case Western Reserve University  Cleveland Ohio"},{"name":"Department of Otolaryngology, Head &amp; 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