{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T01:03:34Z","timestamp":1789607014709,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T00:00:00Z","timestamp":1552608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The study aims to evaluate whether bone scintigraphy is effective in diagnosing temporomandibular joint (TMJ) osteoarthritis (OA) in juvenile patients. A retrospective study was conducted with 356 consecutive patients with TMJ\u2013OA who were clinically assessed according to the Research Diagnostic Criteria for Temporomandibular Disorders. Patients were assigned to three groups based on their ages: Group 1: aged 12\u201316\u00a0years; Group 2: aged 17\u201319\u00a0years; and Group 3: aged 20\u00a0years. Additionally, we performed qualitative and quantitative analyses of bone scintigraphy images for the TMJ uptake ratio of the involved joint. The diagnostic rate of TMJ\u2013OA (<jats:italic>n<\/jats:italic>\u00a0=\u00a0356, 100%), and the overall presence of subjective pain (<jats:italic>n<\/jats:italic>\u00a0=\u00a0282, 77.3%) was closest to the results of bone scintigraphy (<jats:italic>n<\/jats:italic> =\u00a0333, 91.2%). In addition, reported TMJ pain was significantly associated only with the results of bone scintigraphy and not with the results of panoramic radiography or cone beam computed tomography (CBCT) in all age groups. With CBCT as the reference standard, the optimal cutoff values of the uptake ratio for the diagnosis of TMJ\u2013OA were 2.171 and 2.017 in Groups 1 and 2, respectively (<jats:italic>P<\/jats:italic> value\u00a0&lt;\u00a00.05). Our results suggest that bone scintigraphy can be considered a useful modality for diagnosing TMJ\u2013OA in juvenile patients.<\/jats:p>","DOI":"10.1002\/cre2.175","type":"journal-article","created":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T07:35:42Z","timestamp":1552635342000},"page":"225-235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Prediction of painful temporomandibular joint osteoarthritis in juvenile patients using bone scintigraphy"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7323-0411","authenticated-orcid":false,"given":"Yeon\u2010Hee","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Orofacial Pain and Oral Medicine Kyung Hee University Dental Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Il Ki","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Kyung Hee University College of Medicine, Kyung Hee University Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang\u2010Hyun","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Orofacial Pain and Oral Medicine Kyung Hee University Dental Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4329\/wjr.v6.i8.567"},{"issue":"9","key":"e_1_2_9_3_1","first-page":"1925","article-title":"Temporomandibular joint arthritis in juvenile idiopathic arthritis: Prevalence, clinical and radiological signs, and relation to dentofacial morphology","volume":"34","author":"Billiau A. 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