{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:33:44Z","timestamp":1792020824794,"version":"4.4.0"},"reference-count":61,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T00:00:00Z","timestamp":1563408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This retrospective cross\u2010sectional study aimed to evaluate quantitatively the oral microbiome in the tri\u2010lobe central cavity of Locator Legacy attachment and verify whether it harbors a different, potentially more pathogenic, bacterial spectrum than the adjacent edentulous ridge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Edentulous patients rehabilitated with implant overdentures using Locator Legacy attachments were recruited for this study. The clinical examination comprised probing depths, mobility, peri\u2010implant, and periodontal health along with intraoral swabs for microbiological evaluation, polymerase chain reaction (PCR) testing, and candida culture. The swabs were collected from the trilobed cavity of the attachment and the adjacent edentulous ridge. PCR was performed to detect six specific bacteria, <jats:italic>Porphyromonas gingivalis<\/jats:italic>, <jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic>, <jats:italic>Tannerella forsythia<\/jats:italic>, <jats:italic>Treponema denticola<\/jats:italic>, <jats:italic>Prevotella intermedia<\/jats:italic>, and <jats:italic>Parvimonas micra<\/jats:italic>. Statistical analyses were performed using McNemar's test and Wilcoxon's rank sum test with the significance set to <jats:italic>p<\/jats:italic> &lt; .05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 50 participants with a mean age of 71.5 \u00b1 9.6 years participated in the study. No significant differences in the microbiome were found between samples from the ridge and the attachment. No significantly different numbers in the candida cultures were identified, and the presence of a removable prostheses did not demonstrate a significant association with the prevalence of candida.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Within the limits of this study and the investigated bacterial species, the trilobed cavity of the attachment does not seem to increase the bacterial load.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.209","type":"journal-article","created":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T12:41:23Z","timestamp":1563453683000},"page":"476-484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Microbiological evaluation of LOCATOR\u00ae Legacy attachments: A cross\u2010sectional clinical study"],"prefix":"10.1002","volume":"5","author":[{"given":"Ursina","family":"Nagy","sequence":"first","affiliation":[{"name":"Division of Removable Prosthodontics, University Clinics of Dental Medicine University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Gu\u00e9dat","sequence":"additional","affiliation":[{"name":"Division of Removable Prosthodontics, University Clinics of Dental Medicine University of Geneva  Geneva Switzerland"},{"name":"Division of Orthodontics, University Clinics of Dental Medicine University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Giannopoulou","sequence":"additional","affiliation":[{"name":"Division of Periodontology, University Clinics of Dental Medicine University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Schimmel","sequence":"additional","affiliation":[{"name":"Division of Removable Prosthodontics, University Clinics of Dental Medicine University of Geneva  Geneva Switzerland"},{"name":"Division of Gerodontology, School for Dental Medicine University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Division of Removable Prosthodontics, University Clinics of Dental Medicine University of Geneva  Geneva Switzerland"},{"name":"Service of Geriatrics, Department of Internal Medicine, Rehabilitation and Geriatrics Geneva University Hospitals  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3365-576X","authenticated-orcid":false,"given":"Murali","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Division of Removable Prosthodontics, University Clinics of Dental Medicine University of Geneva  Geneva Switzerland"},{"name":"Clinic of General\u2010, Special Care\u2010, and Geriatric Dentistry (KABS), Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2007.08.005"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3913(09)60134-7"},{"issue":"2","key":"e_1_2_8_4_1","first-page":"160","article-title":"Attachment systems for mandibular single\u2010implant overdentures: An in vitro retention force investigation on different designs","volume":"23","author":"Alsabeeha N.","year":"2010","journal-title":"The International Journal of Prosthodontics"},{"issue":"4","key":"e_1_2_8_5_1","first-page":"203","article-title":"Dental status in nursing home residents with domiciliary dental care in Sweden","volume":"34","author":"Andersson P.","year":"2017","journal-title":"Community Dental Health"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.12402"},{"issue":"12","key":"e_1_2_8_7_1","first-page":"784","article-title":"Dysphagia in the elderly","volume":"9","author":"Aslam M.","year":"2013","journal-title":"Gastroenterol Hepatol (N Y)"},{"issue":"4","key":"e_1_2_8_8_1","first-page":"390","article-title":"Oral health status and treatment satisfaction with mandibular implant overdentures and conventional dentures: A randomized clinical trial in a senior population","volume":"16","author":"Awad M. 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