{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T08:48:29Z","timestamp":1791362909986,"version":"4.3.1"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Older people are at increased risk of intraoral yeast colonization. In this observational case series, we assessed <jats:styled-content style=\"fixed-case\"><jats:italic>Candida<\/jats:italic><\/jats:styled-content> colonization among nine nursing home residents to investigate possible correlations with their individual characteristics, general health parameters, and oral care. We also described the effect of professional dental cleaning (PDC) including prosthesis cleaning on colonization cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>General clinical and oral health was assessed in nine residents, and samples were taken from six oral mucosa sites or prosthetic surfaces. PDC was performed to achieve macroscopically clean results, and residents were re\u2010examined 2 weeks later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that six residents were intraorally colonized with <jats:styled-content style=\"fixed-case\"><jats:italic>Candida albicans<\/jats:italic><\/jats:styled-content>; four also had <jats:styled-content style=\"fixed-case\"><jats:italic>Candida glabrata<\/jats:italic><\/jats:styled-content>. Prostheses were particularly infected. Dementia, multimorbidity, and presence of prostheses reduced oral hygiene ability; requiring assistance for oral hygiene care was a risk indicator for <jats:styled-content style=\"fixed-case\"><jats:italic>Candida<\/jats:italic><\/jats:styled-content> colonization. PDC reduced <jats:styled-content style=\"fixed-case\"><jats:italic>C. albicans<\/jats:italic><\/jats:styled-content> (at the expense of increased <jats:styled-content style=\"fixed-case\"><jats:italic>C. glabrata<\/jats:italic><\/jats:styled-content>) but was not optimal for maintaining <jats:styled-content style=\"fixed-case\"><jats:italic>Candida<\/jats:italic><\/jats:styled-content> reduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this pilot study, <jats:styled-content style=\"fixed-case\"><jats:italic>Candida<\/jats:italic><\/jats:styled-content> colonization is prevalent among nursing home residents, especially those with cognitive impairment, multimorbidity, or reduced oral hygiene capacity. Potential negative effects on general health necessitate diagnostic and therapeutic guidelines. PDC alone did not maintain the reduction in <jats:styled-content style=\"fixed-case\"><jats:italic>Candida<\/jats:italic><\/jats:styled-content> colonization; additional methods for daily oral care are necessary.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.238","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T13:39:11Z","timestamp":1568122751000},"page":"683-691","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The underestimated problem of oral <scp><i>Candida<\/i><\/scp> colonization\u2014An observational pilot study in one nursing home"],"prefix":"10.1002","volume":"5","author":[{"given":"Hannah Elisa","family":"Kottmann","sequence":"first","affiliation":[{"name":"Centre of Dental Medicine, Department of Operative Dentistry and Periodontology University of Cologne  K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja Henny Maria","family":"Derman","sequence":"additional","affiliation":[{"name":"Centre of Dental Medicine, Department of Operative Dentistry and Periodontology University of Cologne  K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Johannes","family":"Noack","sequence":"additional","affiliation":[{"name":"Centre of Dental Medicine, Department of Operative Dentistry and Periodontology University of Cologne  K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0169-2582","authenticated-orcid":false,"given":"Anna Greta","family":"Barbe","sequence":"additional","affiliation":[{"name":"Centre of Dental Medicine, Department of Operative Dentistry and Periodontology University of Cologne  K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2007.00233.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.1996.22416.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.1987.tb00713.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/idh.12389"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2487-x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.01.014"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1991.tb00172.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.125"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.1996.tb00239.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0528.2000.028002141.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-006-0029-6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-011-9297-0"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-5229.152757"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199305000-00001"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(90)90152-3"},{"issue":"5","key":"e_1_2_8_17_1","first-page":"153","article-title":"Occurrence of oral \n                     Candida albicans\n                   and other yeast\u2010like fungi in edentulous patients in geriatric units in Iceland","volume":"2","author":"Holbrook W. P.","year":"1986","journal-title":"Gerodontics"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(94)90059-0"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1086\/338404"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.1.328"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90546-0"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345930720060301"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.01391"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1470-9465.2004.t01-1-00844.x"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001432-200204000-00014"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1086\/426023"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-3589(08)60955-2"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.2174\/138945006776359421"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.16.e139"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1989.tb00769.x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1987.tb00488.x"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14260"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1987.tb01741.x"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1991.tb00880.x"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12682"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-016-0246-5"},{"issue":"1","key":"e_1_2_8_37_1","first-page":"27","article-title":"Comparison of oral health among older people with and without dementia","volume":"31","author":"Zenthofer A.","year":"2014","journal-title":"Community Dental Health"}],"container-title":["Clinical and Experimental Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcre2.238","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.238","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cre2.238","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T05:35:22Z","timestamp":1692682522000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cre2.238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,10]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1002\/cre2.238"],"URL":"https:\/\/doi.org\/10.1002\/cre2.238","archive":["Portico"],"relation":{},"ISSN":["2057-4347","2057-4347"],"issn-type":[{"value":"2057-4347","type":"print"},{"value":"2057-4347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,10]]},"assertion":[{"value":"2019-07-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}