{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:39:37Z","timestamp":1762868377626,"version":"3.40.5"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T00:00:00Z","timestamp":1610668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to propose and validate a three\u2010dimensional (3D) methodology for the assessment of canine eruption in patients born with unilateral cleft lip and palate (UCLP) following secondary alveolar bone graft (SABG).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Materials<\/jats:title><jats:p>A total of 10 patients (four females, six males; mean age: 8.8\u2009years) with UCLP who underwent SABG were recruited. Pre\u2010 and 6\u2010month post\u2010operative cone\u2010beam computed tomography (CBCT) was acquired for all patients. Post\u2010operative data was registered onto pre\u2010operative data utilizing voxel\u2010based registration. Following superimposition, a segmentation process was applied to segment maxillary canine on both cleft and non\u2010cleft side. Thereafter, translational and rotational changes in canine position were assessed for both cleft and non\u2010cleft side by two observers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The intra\u2010class correlation coefficient (ICC) indicated excellent reliability (\u22650.90) with inter and intra\u2010observer error of less than 0.05\u2009mm. The overall ICC was found to be high for assessing both translational and rotational changes. The mean absolute inter\u2010 and intra\u2010observer difference for translational and rotational changes was found to be less than 1\u2009mm and 3\u00b0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present method was found to be reliable proving to be clinically applicable for assessing maxillary canine eruption changes in both cleft and non\u2010cleft bone.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.397","type":"journal-article","created":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T03:44:26Z","timestamp":1610768666000},"page":"285-292","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Validation of a novel method for canine eruption assessment in unilateral cleft lip and palate patients"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3106-0770","authenticated-orcid":false,"given":"Khalid","family":"Alqahtani","sequence":"first","affiliation":[{"name":"OMFS IMPATH Research Group, Department of Imaging &amp; Pathology, Faculty of Medicine, KU Leuven &amp; Oral and Maxillofacial Surgery University Hospitals Leuven  Leuven Belgium"},{"name":"Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry Sattam Bin Abdulaziz University  Al\u2010Kharj Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6309-3791","authenticated-orcid":false,"given":"Eman","family":"Shaheen","sequence":"additional","affiliation":[{"name":"OMFS IMPATH Research Group, Department of Imaging &amp; Pathology, Faculty of Medicine, KU Leuven &amp; Oral and Maxillofacial Surgery University Hospitals Leuven  Leuven 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