{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T01:44:20Z","timestamp":1790214260342,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T00:00:00Z","timestamp":1625875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>It was shown, that Connective Tissue Grafts (CTG) retrieved from the tuberosity tends to determine hyperplastic responses and may induce a beneficial over\u2010keratinization of non\u2010keratinized mucosa. Clinically evaluate and compare CTG from tuberosity ability to increase soft tissue thickness and the keratinization potential after recipient area is either prepared using split or full thickness flap in edentulous mandible.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Fourty implants were placed in 10 edentulous patients with atrophied mandible (Class IV of Misch) presenting less than 1.0\u2009mm of keratinized tissue using a flapless approach and immediately restored with acrylic temporary bridge on multi\u2010unit abutments. The surgical sites were split\u2010mouth randomized and prepared as CTG recipients by a tunneling procedure. Twenty benefited of a partial thickness approach and 20 of a full thickness one. The CTG was placed buccally using partial thickness or full thickness flap according to the randomization schedule. The width of keratinized tissue (KT), the horizontal soft tissue thickness (STT), the marginal hard and soft tissue levels as well as the implant success parameters were collected and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After a 3\u00a0year follow\u2010up period the increase of KT was statistically significantly (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) larger in the partial thickness group from 0.6(0.6) to 5.1(0.72) mm, while full thickness group showed very little improvement from 0.5(0.51) to 1(0.57) mm (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). STT was significantly increased in both groups over time: from 2.4(0.88) to 5.4(0.68) mm in full thickness group and from 2.5(0.51) to 5.8(0.41) mm in partial thickness group without any significant difference between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The increase of soft tissue thickness by using CTG from tuberosity was found in both groups, while keratinization of non\u2010keratinized mucosa appeared more in the partial thickness group.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.468","type":"journal-article","created":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T08:50:11Z","timestamp":1625907011000},"page":"1061-1068","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Full versus partial thickness flap to determine differentiation and over keratinization of non\u2010keratinized mucosa. A 3\u2010year split mouth randomized pilot study"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8916-193X","authenticated-orcid":false,"given":"Algirdas","family":"Puisys","sequence":"first","affiliation":[{"name":"Vilnius Research Group VIC Clinic  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktorija","family":"Auzbikaviciute","sequence":"additional","affiliation":[{"name":"VIC Clinic  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Egle","family":"Vindasiute\u2010Narbute","sequence":"additional","affiliation":[{"name":"Institute of Odontology, Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saulius","family":"Zukauskas","sequence":"additional","affiliation":[{"name":"Institute of Odontology, Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dainius","family":"Razukevicus","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Lithuania University of Health Science  Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel M.","family":"Dard","sequence":"additional","affiliation":[{"name":"College of Dental Medicine Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,10]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"479","article-title":"Subpapillary continuous sling suturing method for soft tissue grafting with the tunneling technique","volume":"30","author":"Allen E. 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