{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T13:53:05Z","timestamp":1785851585790,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T00:00:00Z","timestamp":1626393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the survival rates of pulpectomized primary teeth treated under general anesthesia (GA) or local anesthesia (LA), and to determine which factors affected tooth survival following pulpectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This retrospective study collected data from dental records. Patients under 5\u2009years of age received dental treatment under GA or LA during 2007\u20132016, with at least one anterior or posterior tooth receiving a pulpectomy, were recruited. Pulpectomy was considered a failure if the tooth required extraction or retreatment due to pulp treatment failure. Survival analysis was used to assess the outcome. The cumulative survival probability was analyzed with the Kaplan\u2013Meier estimator. Cox regression analysis was used to evaluate the associations between tooth survival and possible prognosis factors; sex, age, dental arch (upper\/lower), tooth type (anterior\/posterior), molar type (first\/second molar), molar location (upper\/lower molar), root filling material type, restoration type, preoperative radiographic findings and presence of pathologic root resorption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and twenty\u2010seven primary teeth were included. At the 5\u2010year follow\u2010up, the survival rates of the pulpectomized teeth treated under GA and LA were 81.4% and 87.4%, respectively, which were not significantly different (<jats:italic>p<\/jats:italic>\u00a0\u2265\u20090.05). A radiolucency on the preoperative radiograph was the only factor associated with tooth extraction or retreatment following pulpectomy, with a hazard ratio of 3.88 (95% CI\u00a0=\u00a01.29\u201311.65).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pulpectomized primary teeth treated under GA and LA demonstrated high survival rates. Preoperative radiolucency is a possible associated factor that decreases tooth survival following pulpectomy.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p><jats:bold>Why this paper is important<\/jats:bold><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Pulpectomy treatment under GA and LA provided high 5\u2010year cumulative survival rates, which were not significantly different.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Pulpectomy treatment in teeth with a preoperative radiolucency were 3.9\u2010fold as likely to fail as teeth without pathology.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Based on our findings, practitioners could apply these findings and discuss with caregivers about the treatment options, outcomes, and prognosis of pulpectomized teeth.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.473","type":"journal-article","created":{"date-parts":[[2021,7,17]],"date-time":"2021-07-17T06:41:21Z","timestamp":1626504081000},"page":"978-986","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Survival rate and associated factors affecting pulpectomy treatment outcome in primary teeth"],"prefix":"10.1002","volume":"7","author":[{"given":"Methaphon","family":"Songvejkasem","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dentistry Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6505-3424","authenticated-orcid":false,"given":"Prim","family":"Auychai","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dentistry Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oitip","family":"Chankanka","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, Faculty of Dentistry Prince of Songkla University  Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0355-4175","authenticated-orcid":false,"given":"Siriporn","family":"Songsiripradubboon","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Faculty of Dentistry Chulalongkorn University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2010.00580.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12134"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.27.2.k3307186n7086r11"},{"key":"e_1_2_9_5_1","first-page":"353","volume-title":"The reference manual of pediatric dentistry","author":"American Academy of Pediatric Dentistry","year":"2019"},{"issue":"4","key":"e_1_2_9_6_1","first-page":"317","article-title":"Success rate of treatments provided for early childhood caries under general anesthesia: A retrospective cohort study","volume":"38","author":"Amin M.","year":"2016","journal-title":"Pediatric Dentistry"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01476.x"},{"issue":"3","key":"e_1_2_9_8_1","first-page":"209","article-title":"The effect of nursing or rampant caries on height, body weight and head circumference","volume":"20","author":"Ayhan H.","year":"1996","journal-title":"Journal of Clinical Pediatric Dentistry"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4625-43.6.9"},{"issue":"3","key":"e_1_2_9_10_1","first-page":"210","article-title":"Pediatric and general dentists' attitudes toward pulp therapy for primary teeth","volume":"34","author":"Bowen J. 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