{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:26:15Z","timestamp":1790799975702,"version":"4.1.0"},"reference-count":77,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T00:00:00Z","timestamp":1630195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>In patients with end stage, renal disease a high rate of morbidity and mortality is present. Studies suggest that end stage renal disease may affect oral health. Therefore, the aim of this study was to perform a scoping review on periodontal disease, dental caries, xerostomia, and hyposalivation in end stage renal disease patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>A literature search (in PubMed and Embase.com) was performed up to September 29, 2020, in collaboration with a medical information specialist. Included outcome variables were the community periodontal index, probing pocket depth, gingival index, bleeding on probing, decayed\u2010missing\u2010filled\u2010teeth, carious\u2010absent\u2010obturated index, Xerostomia Inventory and the (un)stimulated whole salivary flow rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty three out of 1293 studies were included in the final review comprising 7757 end stage renal disease patients. The average age was 58.3\u2009\u00b1\u200929.4\u2009years. 28.2%\u201378.8% of patients reported xerostomia and the (un)stimulated salivary flow rates were significantly lower. Higher community periodontal index scores were measured in end stage renal disease patients. More decayed\u2010missing\u2010filled\u2010teeth were recorded, but no differences were found between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Xerostomia and hyposalivation were highly prevalent in end stage renal disease patients. Patients have more deepened pockets, but an equal number of carious teeth compared to healthy controls.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.479","type":"journal-article","created":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T23:54:16Z","timestamp":1630281256000},"page":"54-67","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Oral health in patients with end\u2010stage renal disease: A scoping review"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1291-2798","authenticated-orcid":false,"given":"Alexa","family":"Laheij","sequence":"first","affiliation":[{"name":"Department of Oral Medicine, Academic Center for Dentistry Amsterdam University of Amsterdam and VU University Amsterdam  Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wietse","family":"Rooijers","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Academic Center for Dentistry Amsterdam University of Amsterdam and VU University Amsterdam  Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lela","family":"Bidar","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Academic Center for Dentistry Amsterdam University of Amsterdam and VU University Amsterdam  Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lema","family":"Haidari","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Academic Center for Dentistry Amsterdam University of Amsterdam and VU University Amsterdam  Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aegida","family":"Neradova","sequence":"additional","affiliation":[{"name":"Department of Nephrology Dianet Amsterdam, and Amsterdam UMC  Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"de Vries","sequence":"additional","affiliation":[{"name":"Medical Library VU University  Amsterdam Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik","family":"Rozema","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Academic Center for Dentistry Amsterdam University of Amsterdam and VU University Amsterdam  Netherlands"},{"name":"Department of Oral and Maxillofacial Surgery Amsterdam UMC, location AMC  Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,29]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"343","article-title":"Dental diseases in a Jordanian population on renal dialysis","volume":"34","author":"Al\u2010Wahadni A.","year":"2003","journal-title":"Quintessence International"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2011111078"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2007.01372.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kisu.2017.07.007"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12821"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2011.218"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/bdj.2007.47"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00933.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01183.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1179\/1743291X14Y.0000000118"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.26111"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-013-0576-y"},{"key":"e_1_2_8_14_1","first-page":"e406","article-title":"Xerostomia, thirst, sodium gradient and inter\u2010dialytic weight gain in hemodialysis diabetic vs. non\u2010diabetic patients","volume":"23","author":"Bruzda\u2010Zwiech A.","year":"2018","journal-title":"Medicina Oral, Patologia Oral y Cirugia Bucal"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2017.181"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139x.2006.00175.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.06.078"},{"key":"e_1_2_8_18_1","first-page":"467","article-title":"Oral mucosa symptoms, signs and lesions, in end stage renal disease and non\u2010end stage renal disease diabetic patients","volume":"11","author":"Rosa Garc\u00eda E.","year":"2006","journal-title":"Medicina Oral, Patolog\u00eda Oral y Cirug\u00eda Bucal"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1996.0171"},{"key":"e_1_2_8_20_1","first-page":"127","article-title":"Clinical oral findings in dialysis and kidney\u2010transplant patients","volume":"42","author":"Dirschnabel A. 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