{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T09:51:53Z","timestamp":1766137913635,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T00:00:00Z","timestamp":1644796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003776","name":"Newcastle upon Tyne Hospitals NHS Foundation Trust","doi-asserted-by":"publisher","award":["AG\/ML\/013"],"award-info":[{"award-number":["AG\/ML\/013"]}],"id":[{"id":"10.13039\/501100003776","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Concern that facial swelling after dental extractions will spoil the fit of radiotherapy masks in head and neck cancer patients leads to the current practice of delay making of mask production (and therefore the start of radiotherapy) for several days or longer. However, there is little data on how extensive facial swelling is after dental extraction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the degree of facial swelling in a group of adult patients attending Newcastle Dental School for routine dental extractions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Seventeen dental extraction patients underwent three\u2010dimensional photography using the 3dMDFace\u00ae system at 1\u2010week preop, immediately preop, and at 48\u2010h postop. We recorded demographic data, teeth extracted, and methods. Facial volume change was assessed using 3dMD Vultus\u00ae software. Two reviewers ran the data through the 3dMD Vultus\u00ae software independently. We used Student's <jats:italic>t<\/jats:italic>\u2010test to assess significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve patients were included in the final analysis. There was no significant difference in the difference between the two preoperative measurements and the preoperative versus postoperative difference (Wilcoxon signed\u2010rank test: Reviewer 1: <jats:italic>p<\/jats:italic>\u2009=\u2009.31. and Reviewer 2: <jats:italic>p<\/jats:italic>\u2009=\u2009.10). Thus, mean facial swelling was less than the threshold for significant swelling which was deemed to be 15\u2009cm<jats:sup>3<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Facial swelling following dental extraction may not be sufficient in itself to justify the current delays in mask production and subsequent delivery of radiotherapy. Further definitive studies are needed to optimize how dental extractions should be timed within head and neck cancer care pathways.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.540","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T19:50:09Z","timestamp":1644868209000},"page":"583-588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Is the degree of facial swelling after dental extraction sufficient to justify the current delays to radiotherapy mask production? A pilot evaluation of postextraction swelling using 3D photography"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9187-2992","authenticated-orcid":false,"given":"Robert","family":"McCormick","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Newcastle Upon Tyne Hospitals NHS Foundation Trust  Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Meechan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Newcastle Upon Tyne Hospitals NHS Foundation Trust  Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Newcastle Upon Tyne Hospitals NHS Foundation Trust  Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Stanncliffe","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Newcastle Upon Tyne Hospitals NHS Foundation Trust  Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee","family":"Merecer","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Newcastle Upon Tyne Hospitals NHS Foundation Trust  Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Best","sequence":"additional","affiliation":[{"name":"Newcastle University Faculty of Humanities and Social Sciences  Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2685-2426","authenticated-orcid":false,"given":"Michael","family":"Nugent","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Newcastle Upon Tyne Hospitals NHS Foundation Trust  Newcastle Upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,14]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"3dMD LLC.2021.3dMD\u2026 Welcome to the 4D Revolution.http:\/\/www.3dMD.com"},{"issue":"6","key":"e_1_2_11_3_1","first-page":"e1","article-title":"The efficacy of 2 different doses of dexamethasone to control postoperative swelling, trismus, and pain after third molar extractions","volume":"62","author":"Agostinho C. N.","year":"2014","journal-title":"General Dentistry"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30959"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(83)90227-X"},{"issue":"9","key":"e_1_2_11_6_1","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.4103\/njcp.njcp_38_18","article-title":"Three\u2010dimensional evaluation of the effect of low\u2010level laser therapy on facial swelling after lower third molar surgery: A randomized, placebocontrolled study","volume":"21","author":"Asutay F.","year":"2018","journal-title":"Nigerian Journal of Clinical Practice"},{"key":"e_1_2_11_7_1","unstructured":"British Association of Head and Neck Oncologists(2009). BAHNO Standards 2009.http:\/\/www.bahno.org.uk\/wp-content\/uploads\/2014\/03\/BAHNO-STANDARDS-DOC09.pdf"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0266-4356(85)90074-9"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(99)90486-X"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-117X(79)80037-2"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0300-1652.190599"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-6343.2006.00341.x"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.04.022"},{"issue":"7","key":"e_1_2_11_14_1","first-page":"1036","article-title":"Three\u2010dimensional quantitative evaluation of the effect of local administration of dexamethasone on facial swelling after impacted mandibular third molar extraction","volume":"2","author":"Matsuda M.","year":"2016","journal-title":"Journal of Dentistry & Oral Disorders"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(10)80041-2"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(85)90255-1"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(96)90441-3"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2015.08.017"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/1721727X0700500306"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-015-0795-0"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13161"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2011.03.225"},{"key":"e_1_2_11_23_1","doi-asserted-by":"crossref","unstructured":"Ullah R.(2014).The validity of 3dMD Vultus in predicting soft tissue morphology following orthognathic surgery[Doctoral dissertation]. University of Birmingham.","DOI":"10.1016\/j.bjoms.2014.07.053"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2014.11.001"}],"container-title":["Clinical and Experimental Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.540","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cre2.540","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.540","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T20:04:22Z","timestamp":1692993862000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cre2.540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,14]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1002\/cre2.540"],"URL":"https:\/\/doi.org\/10.1002\/cre2.540","archive":["Portico"],"relation":{},"ISSN":["2057-4347","2057-4347"],"issn-type":[{"type":"print","value":"2057-4347"},{"type":"electronic","value":"2057-4347"}],"subject":[],"published":{"date-parts":[[2022,2,14]]},"assertion":[{"value":"2021-06-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}