{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:01:18Z","timestamp":1791525678111,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T00:00:00Z","timestamp":1648425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Dental Res"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Health\u2010related quality of life (HRQoL) of orofacial pain patients is lower than that of the general population and impaired in multiple dimensions. The aim of the present study was to investigate HRQoL of orofacial pain patients in comparison with patients suffering from other chronic pain disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>One hundred and fifty\u2010one tertiary care facial pain patients (mean age, 50 years; standard deviation [SD], 15; 119 females), were compared with 312 other non\u2010cancer chronic pain patients (mean age, 46 years; SD, 13; 204 women), recruited from three multidisciplinary pain clinics in Finland. The groups were compared using the 15D, and pain\u2010related measures such as pain interference, pain acceptance, anxiety, depression, and sleep. Statistical comparisons between groups were done using <jats:italic>t<\/jats:italic> test,\u00a0<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> test, or analysis of covariance. Multivariate linear regression analysis was used to study whether pain\u2010related aspects influencing HRQoL are similar between the patient groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 15D score was significantly higher in facial pain patients (0.823; SD, 0.114) indicating better HRQoL in comparison with other chronic pain patients (0.732; SD, 0.107) (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). The 15D profiles of studied populations resembled each other but orofacial pain patients showed significantly higher scores for most individual 15D dimensions. Dimensions regarding discomfort and symptoms and sleep were most affected in both groups. Orofacial pain patients showed less psychosocial disability and better acceptance of their pain. Pain acceptance was a weaker explanatory factor of HRQoL in orofacial pain patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared to other non\u2010cancer chronic pain, chronic pain in the orofacial area causes less impairment in HRQoL. Orofacial pain patients showed less psychosocial disability and better pain acceptance.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.560","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T02:44:27Z","timestamp":1648521867000},"page":"742-749","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Health\u2010related quality of life in patients with chronic orofacial pain compared with other chronic pain patients"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6423-6811","authenticated-orcid":false,"given":"Johanna","family":"Tanner","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Diseases Turku University Hospital Turku Finland"},{"name":"Department of Prosthetic Dentistry and Stomatognathic Physiology University of Turku Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuija","family":"Teerijoki\u2010Oksa","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Diseases Turku University Hospital Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannu","family":"Kautiainen","sequence":"additional","affiliation":[{"name":"Primary Health Care Unit Kuopio University Hospital Kuopio Finland"},{"name":"Folkh\u00e4lsan Research Center Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pekka","family":"Vartiainen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Intensive Care, and Pain Medicine, Division of Pain Medicine Helsinki University Hospital and University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eija","family":"Kalso","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Department of Pharmacology, Intensive Care and Pain Medicine, Helsinki University Hospital SleepWell Research Programme University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9842-8739","authenticated-orcid":false,"given":"Heli","family":"Forssell","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Institute of Dentistry University of Turku Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa6703_13"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1961.01710120031004"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001435"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/cku174"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1532-2149.2013.00297.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2005.06.009"},{"key":"e_1_2_10_8_1","first-page":"129","article-title":"Pain assessment: Global use of the Brief Pain Inventory","volume":"23","author":"Cleeland C. 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