{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T02:25:24Z","timestamp":1781058324213,"version":"3.54.1"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to investigate whether a low\u2010dose cone\u2010beam computed tomography (CBCT) protocol provides diagnostically acceptable image quality for assessing bone healing after alveolar bone grafting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>The study cohort comprised 11 patients (aged 7\u201314 years) with orofacial clefts who had undergone alveolar bone grafting at Sk\u00e5ne University Hospital in Malm\u00f6, Sweden. During the postsurgical follow\u2010up at 6 months, each patient was assessed twice: once with a standard\u2010dose CBCT protocol and once with a low\u2010dose CBCT protocol, which in total corresponds to one CBCT examination made with the exposure settings recommended by the manufacturer. Among others, the assessed parameters included subjective image quality, as well as bone graft height, thickness, and integration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences were found between the standard\u2010 and low\u2010dose protocols for most parameters (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). Exceptions included subjective image quality (one observer, <jats:italic>p<\/jats:italic>\u2009=\u20090.05) and confidence levels during the assessment (three observers, <jats:italic>p<\/jats:italic>\u2009=\u20090.01, 0.01, 0.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The low\u2010dose protocol yielded adequate image quality for postoperative CBCT healing assessment in patients who have undergone alveolar bone grafting. However, the confidence level of observers during the assessment with the low\u2010dose protocol was reduced. This study is registered on <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/ClinicalTrials.gov\">ClinicalTrials.gov<\/jats:ext-link> (NCT06395077).<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Trial Registration<\/jats:title><jats:p>This study is registered on <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/ClinicalTrials.gov\">ClinicalTrials.gov<\/jats:ext-link> (NCT06395077).<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.70021","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T05:39:49Z","timestamp":1730785189000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Low\u2010Dose Cone\u2010Beam Computed Tomography in Swedish Pediatric Patients With Alveolar Clefts Following Alveolar Bone Grafting\u2014A Clinical Study"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0252-4165","authenticated-orcid":false,"given":"Ant\u00f3nio","family":"Vicente","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4611-3708","authenticated-orcid":false,"given":"Josefine","family":"Cederhag","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0025-8023","authenticated-orcid":false,"given":"Nilofar","family":"Rashidi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6088-1143","authenticated-orcid":false,"given":"Anna\u2010Paulina","family":"Wiedel","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Sk\u00e5ne University Hospital Malm\u00f6 Sweden"},{"name":"Department of Orthodontics, Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"},{"name":"Department of Clinical Sciences in Malm\u00f6 Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1915-1736","authenticated-orcid":false,"given":"Magnus","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences in Malm\u00f6 Lund University Malm\u00f6 Sweden"},{"name":"Department of Plastic and Reconstructive Surgery Sk\u00e5ne University Hospital Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2745-1816","authenticated-orcid":false,"given":"Susanne","family":"Brog\u00e5rdh\u2010Roth","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6967-4407","authenticated-orcid":false,"given":"Xie\u2010Qi","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"},{"name":"Section of Oral and Maxillofacial Radiology, Department of Clinical Dentistry University of Bergen Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9885-0019","authenticated-orcid":false,"given":"Kristina","family":"Hell\u00e9n\u2010Halme","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Faculty of Odontology Malm\u00f6 University Malm\u00f6 Sweden"},{"name":"Section of Oral and Maxillofacial Radiology, Department of Clinical Dentistry University of Bergen Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2015150050"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-020-00544-8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2019.10.010"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjac004"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016357.2023.2170462"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20220176"},{"key":"e_1_2_11_8_1","unstructured":"European Commission.2012.Radiation Protection N 172 Cone Beam CT for Dental and Maxillofacial Radiology. 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