{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T18:55:27Z","timestamp":1784228127707,"version":"3.55.0"},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T00:00:00Z","timestamp":1728777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to investigate whether periodontal condition is associated with the development of impaired glucose tolerance (IGT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>This study was based on a subpopulation of a cohort of persons born in 1935 and living in Oulu, Finland, on October 1, 1990. The participants were normoglycemic (no previously diagnosed diabetes mellitus and a 2\u2010h oral glucose tolerance test [OGTT] blood glucose &lt;\u20097.8\u2009mmol\/L) in the baseline examinations (1990\u20131992) and had fasting blood glucose &lt;\u20097.0\u2009mmol\/L in the follow\u2010up examinations (2007\u20132008) (<jats:italic>n<\/jats:italic>\u2009=\u2009225). The outcome was IGT on follow\u2010up, measured by a blood glucose level of \u2265\u20097.8\u2009mmol\/L after OGTT. The exposure was the periodontal condition at baseline categorized into four groups: 0, 1\u20136, \u2265\u20097 sites with deepened (\u2265\u20094\u2009mm) periodontal pockets, and edentulousness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 23% of the participants developed IGT. The adjusted incidence rate ratios with 95% confidence intervals (CI) for dentate participants with 1\u20136 sites and \u2265\u20097 sites with deepened periodontal pockets, and edentate participants (reference category dentate participants without deepened periodontal pockets) were 1.5 (95% CI, 0.6\u20134.0), 1.8 (95% CI, 0.7\u20134.4), and 1.6 (95% CI, 0.6\u20134.0), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Poor periodontal condition may predispose individuals to IGT; however, further studies on this matter are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.70023","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T06:40:47Z","timestamp":1728888047000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of Periodontal Condition With Impaired Glucose Tolerance: Results of a 15\u2010Year Follow\u2010Up 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