{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:17:34Z","timestamp":1793121454526,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study evaluates the efficacy of polyvinylpyrrolidone\u2013sodium hyaluronate (PVP\u2010SH) gel as a dressing material in enhancing both clinical and patient\u2010reported outcomes post\u2010free gingival graft (FGG) harvesting from the hard palate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This randomized clinical trial included 18 patients and spanned from June 2022 to August 2023. Patients received an FGG procedure to manage a lack of attached gingiva. Following graft harvesting, patients were divided into two groups: the control group, which received Coe\u2010Pak, and the test group, which was treated with PVP\u2010SH gel. The primary outcome measured was complete epithelialization. Secondary outcomes included the Landry healing scale, post\u2010operative pain level, and patient willingness to receive the same treatment again.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The test group reported significantly lower analgesic use (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and reduced pain severity (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) compared to the control group. Furthermore, test group patients indicated a higher level of satisfaction regarding the prospect of retreatment. In contrast, the control group showed significantly slower progress in wound healing and epithelization (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) compared to the test group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings of this study suggest that PVP\u2010SH gel is a superior dressing material post\u2010FGG harvesting, yielding improved clinical and patient\u2010reported outcomes relative to Coe\u2010Pak.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70026","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T01:45:31Z","timestamp":1731375931000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical and Patient\u2010Reported Outcome Measures of Palatal Donor Site Healing Using Polyvinylpyrrolidone\u2013Sodium Hyaluronate Gel as a Dressing Material Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8861-4312","authenticated-orcid":false,"given":"Mohammad","family":"Baroudi","sequence":"first","affiliation":[{"name":"Department of Periodontology, Faculty of Dental Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majd","family":"Othman","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Faculty of Dental Medicine Damascus University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-022-04848-5"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-006-0171-1"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.22-0172"},{"issue":"1","key":"e_1_2_11_5_1","first-page":"17","article-title":"Preliminary Study of Orassist (Gelclair) in the Management of Oral Mucositis","volume":"26","author":"Berndtson M.","year":"2001","journal-title":"Swed Hosp Dent"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1517\/17425255.4.11.1449"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.4494"},{"key":"e_1_2_11_8_1","unstructured":"De Cordi M. P.D'andrea E.Giorgiutti andS.Martina.2001. Gelclair Potentially an Efficacious Treatment for Chemotherapy\u2010Induced Mucositis. Conegliano Italy: Italian Tumour League III Congress for Professional Oncology Nurses."},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/jisp.jisp_688_18"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jebdp.2017.05.008"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-021-01611-2"},{"issue":"5","key":"e_1_2_11_12_1","first-page":"408","article-title":"Patient\u2010Reported Outcome Measures of Leucocyte\u2010and Platelet\u2010Rich Fibrin (L\u2010PRF) or Hemostatic Agent Application at Palatal Donor Sites After Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial","volume":"54","author":"Gatti F.","year":"2023","journal-title":"Quintessence International (Berlin, Germany: 1985)"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2005.12.004"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(02)00524-9"},{"issue":"24","key":"e_1_2_11_15_1","first-page":"163","article-title":"Comparative Evaluation of Healing After Frenectomy Using Different Techniques \u2013 A Case Series","volume":"8","author":"Kalaiyazhagi M.","year":"2023","journal-title":"International Journal of Chemical and Biochemical Sciences"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.5301\/jabfm.5000215"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12404"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-021-04197-9"},{"key":"e_1_2_11_19_1","unstructured":"Landry R. G.1985.Effectiveness of Benzydamine HC1 in the Treatment of Periodontal Post\u2010Surgical Patients. Faculty of Dentistry University of Toronto."},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.12.715"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-021-03933-5"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.19-0640"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.290910.x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2020.03.017"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000000366"},{"issue":"607","key":"e_1_2_11_26_1","first-page":"1004","article-title":"The Efficacy of Oral Hydrogel Containing Hyaluronic Acid, Polyvinylpyrrolidone, and Glycyrrhizin for Prevention and Treatment of Oral Mucositis Induced by Chemotherapy","volume":"38","author":"Rezazadeh M.","year":"2021","journal-title":"Journal of Isfahan Medical School"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma17051221"},{"issue":"1","key":"e_1_2_11_28_1","first-page":"69","article-title":"Comparison of Effects of PRF Dressing in Wound Healing of Palatal Donor Site Turing Free Gingival Grafting Procedures With No Dressing at the Donor Site","volume":"4","author":"Shakir Q. J.","year":"2015","journal-title":"Journal of Research and Advancement in Dentistry"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-023-05296-5"},{"issue":"3","key":"e_1_2_11_30_1","first-page":"121","article-title":"Free Autogenous Gingival Graft. I. Principles of Successful Grafting","volume":"6","author":"Sullivan H.","year":"1968","journal-title":"Periodontics"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.21608\/ajdsm.2020.26633.1047"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-021-06573-z"}],"container-title":["Clinical and Experimental Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.70026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T12:24:22Z","timestamp":1734611062000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cre2.70026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,11]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/cre2.70026"],"URL":"https:\/\/doi.org\/10.1002\/cre2.70026","archive":["Portico"],"relation":{},"ISSN":["2057-4347","2057-4347"],"issn-type":[{"value":"2057-4347","type":"print"},{"value":"2057-4347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,11]]},"assertion":[{"value":"2024-06-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70026"}}