{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:24:43Z","timestamp":1789611883663,"version":"build-2803163510"},"reference-count":73,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This retrospective cohort study aimed to assess the survival rate of implants placed in grafted edentulous maxillary arches following a delayed loading protocol versus a graftless approach with an immediate loading protocol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Eighty seven patients with atrophic edentulous maxillae were included in two groups: Group\u20101 (GG group,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009155 implants): 26 patients that underwent maxillary bone grafting before treatment with axially placed delayed loading implants and provided with a fixed full\u2010arch prostheses; Group\u20102 (GL group;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009244 implants): 61 patients who received axial and tilted implants without bone augmentation followed by an immediately loaded fixed full\u2010arch prostheses. Patients were followed up for up to 10 years. Kaplan\u2013Meier and Mantel\u2013Cox analyses were performed to determine implant survival rates, and a Cox hazards model was run to assess the influence of patient, implant, and prosthesis\u2010based covariates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were no significant differences in implant failure rates between the two treatment groups (p\u2009=\u20090.298). Five implant failures were observed in Group\u20101 (GG group) and four failures were observed in Group\u20102 (GL group) (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u20099). Survival rate was 96.8% and 98.4% in the GG and GL groups, respectively. No significant association between patient and implant\u2010based covariates and implant failure was observed in both groups; however, a significant association was observed regarding the nature of the opposing arch (p\u2009=\u20090.019).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Immediately loaded implants placed in maxillary native bone show statistically similar survival rates compared to implants placed in grafted bone following a delayed loading. The nature of the opposing arch may negatively influence the survival rate of dental implants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Significance<\/jats:title>\n                    <jats:p>For atrophic edentulous maxillae, both grafted and graftless approach may represent a viable treatment modality in the long term.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70167","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T21:49:39Z","timestamp":1763502579000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Rehabilitation of the Atrophic Edentulous Maxilla: A Retrospective Cohort Study Comparing Survival of Delayed\u2010Loaded Implants in Grafted Bone Versus Immediately Loaded Implants in Native Bone"],"prefix":"10.1002","volume":"11","author":[{"given":"Evelina","family":"Haroyan\u2010Darbinyan","sequence":"first","affiliation":[{"name":"Faculty of Dental Medicine and Oral Health Sciences McGill University, Strathcona Anatomy and Dentistry Building Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiman","family":"Gao","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine and Oral Health Sciences McGill University, Strathcona Anatomy and Dentistry Building Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"de Lillo","sequence":"additional","affiliation":[{"name":"Faculty of Statistics Complutense University of Madrid (U.C.M) Madrid Comunidad de Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Torres","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Complutense University of Madrid (U.C.M) Madrid Comunidad de Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samer","family":"Abi\u2010Nader","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine and Oral Health Sciences McGill University, Strathcona Anatomy and Dentistry Building Montreal Quebec Canada"},{"name":"East Coast Oral Surgery Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Nach","sequence":"additional","affiliation":[{"name":"East Coast Oral Surgery Moncton New Brunswick Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faleh","family":"Tamimi","sequence":"additional","affiliation":[{"name":"College of Dental Medicine. 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