{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:37:41Z","timestamp":1786977461620,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The impact of orthodontic forces on pulp stone formation has been the focus of several studies. Given that orthodontic extractions typically involve the application of greater forces to the teeth, the aim of this study was to compare the extent of pulp stone formation in the molar teeth of patients undergoing orthodontic treatment with and without extractions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      In this retrospective observational study, panoramic radiographs of 80 orthodontic patients taken between 2014 and 2020 (equally divided into extraction and non\u2010extraction groups) who had a full set of permanent molars were analyzed before and after orthodontic treatment to assess the formation of pulp stones in the pulp chambers of the molar teeth (640 molars). Data were analyzed using the Chi\u2010square and McNemar tests with a significance level set at\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05, using SPSS software.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The frequency of pulp stone formation significantly increased in both the extraction and non\u2010extraction groups following fixed orthodontic treatment (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02, respectively). However, no statistically significant difference was observed in the extent of pulp stone formation between the two groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.09). The frequency of patients exhibiting pulp stone formation did not differ significantly by gender in either the extraction or non\u2010extraction treatment groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.392 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.451, respectively). In the extraction group, the prevalence of pulp stones was significantly higher in the first molar compared to the second molar (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). In contrast, no significant difference was found between the first and second molars in the non\u2010extraction group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.108). Additionally, no correlation was found between the frequency of pulp stone formation and jaw type (maxilla or mandible) in either group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Fixed orthodontic treatment is associated with increased pulp stone formation, regardless of whether extractions are performed. These findings may help clinicians in the early identification and monitoring of at\u2010risk teeth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70181","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T18:18:06Z","timestamp":1753381086000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pulp Stone Formation Following Fixed Orthodontic Treatment: A Panoramic Radiographic Comparison of Extraction and Non\u2010Extraction Approaches"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6047-4005","authenticated-orcid":false,"given":"Kosar","family":"Gholinezhad","sequence":"first","affiliation":[{"name":"Student Research Committee Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2952-3273","authenticated-orcid":false,"given":"Hakimeh","family":"Ghorbani","sequence":"additional","affiliation":[{"name":"Oral Health Research Center, Health Research Institute Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3841-0609","authenticated-orcid":false,"given":"Seyedali","family":"Seyedmajidi","sequence":"additional","affiliation":[{"name":"Dental Materials Research Center, Health Research Institute Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4022-2164","authenticated-orcid":false,"given":"Sedigheh","family":"Sheikhzadeh","sequence":"additional","affiliation":[{"name":"Dental Materials Research Center, Health Research Institute Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7561-5948","authenticated-orcid":false,"given":"Manouchehr","family":"Rahmati Kamel","sequence":"additional","affiliation":[{"name":"Oral Health Research Center, Health Research Institute Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.18502\/fid.v18i22.6932"},{"issue":"7","key":"e_1_2_12_3_1","first-page":"1990","article-title":"Prevalence of Pulp Stones in Molars Regarding the Dental Arches","volume":"4","author":"Aleksova P.","year":"2015","journal-title":"International Journal of Scientific Research"},{"key":"e_1_2_12_4_1","volume-title":"Textbook and Color Atlas of Traumatic Injuries to the Teeth","author":"Andreasen J. 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