{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T13:28:15Z","timestamp":1767014895033,"version":"3.48.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004847","name":"Zahedan University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004847","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to investigate the discoloration of anterior teeth with three types of substances used in endodontic treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In this laboratory study, 75 newly extracted human anterior (central and lateral) teeth with full roots were examined. This study utilized the following materials: AH26, MTA Base (Maruchi), a novel formulation containing nano\u2010zinc particles, and a second novel formulation containing both nano\u2010zinc and nano\u2010copper particles. The teeth in the first three groups were dried with paper points, and the canals were completely sealed using the sealer lateral filling technique with gutta\u2010percha. Then the color of the samples was measured by a spectrophotometer at four times: initially, immediately after filling (0), 14 days, and 28 days later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The results showed that the mean color change (\u2206E) at all times (immediately, 14 days later, and 28 days later) was statistically significant between all groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). The degree of color change decreased in the following order: AH26\u2009&gt;\u2009Zn\u2010nano\u2009&gt;\u2009Zn.Cu\u2010nano\u2009&gt;\u2009novel nano\u2010zinc\/copper material\u2009&gt;\u2009MTA Base (Maruchi)\u2009&gt;\u2009control group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of the present study showed that sealers with a zinc base (Zn\u2010nano and Zn.Cu\u2010nanoparticles) had an appropriate color change. Therefore, they can be used alongside other sealers available in the market.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70204","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T07:12:58Z","timestamp":1761721978000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Investigation of Discoloration of Anterior Teeth With Three Types of Substances Used in Endodontic Treatment"],"prefix":"10.1002","volume":"11","author":[{"given":"Sahar","family":"Soltani","sequence":"first","affiliation":[{"name":"Zahedan University of Medical Sciences  Sistan and Baluchestan Province Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eshagh Ali","family":"Saberi","sequence":"additional","affiliation":[{"name":"Oral and Dental Disease Research Center Zahedan University of Medical Sciences Zahedan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0641-2825","authenticated-orcid":false,"given":"Nazanin","family":"Shahradnia","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Deparment of Restorative and aesthetic dentistry, Student Research Committee Zahedan University of Medical Sciences  Sistan and Baluchestan Province Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedram Abdollahzade","family":"Sangrodi","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Deparment of Restorative and aesthetic dentistry, Student Research Committee Zahedan University of Medical Sciences  Sistan and Baluchestan Province Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Majidi","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Deparment of Restorative and aesthetic dentistry, Student Research Committee Zahedan University of Medical Sciences  Sistan and Baluchestan Province Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.identj.2023.04.003"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.5395\/rde.2019.44.e10"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2012.02071.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/563203"},{"issue":"3","key":"e_1_2_11_6_1","first-page":"183","article-title":"Evaluation of Chemical and Physical Properties of an Experimental Endodontic Sealer in Comparison With AH\u201026 and AH\u2010Plus","volume":"15","author":"Ashraf H.","year":"2020","journal-title":"Iranian Endodontic Journal"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.04.003"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12572"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.33899\/rden.2020.166457"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2629-1"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.18-0467"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.11.053"},{"key":"e_1_2_11_13_1","first-page":"11","article-title":"Comparison of the Antibacterial Effect of AH26, Adseal and Beta RCS Root Canal Sealers Against Enterococcus faecalis, an In Vitro Study","volume":"21","author":"Ghabraei S.","year":"2024","journal-title":"Frontiers in Dentistry"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/edt.12552"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757201302254"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2012.02098.x"},{"issue":"4","key":"e_1_2_11_17_1","first-page":"146","article-title":"Comparing Coronal Discoloration Between AH26 and ZOE Sealers","volume":"6","author":"Jahromi M. 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