{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T14:00:51Z","timestamp":1784642451529,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Vertical root fracture (VRF) in endodontically treated molars (ETMs) is a multifactorial condition. However, the relationship between residual pericervical and apical dentine in ETMs and VRF has yet to be fully assessed. This study aimed to investigate the association between residual pericervical and apical dentine and VRF in ETMs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>ETMs with VRFs (44 cases) and those without VRFs (92 controls) were included. Residual dentine at pericervical level and apical terminus of root canal filling (RCF) were assessed based on the ratio between the mesiodistal widths of the RCF and root on periapical radiographs. The ratio was converted into four categories: \u201cintact canal\u201d, \u201cminimum preparation\u201d, \u201ctraditional preparation\u201d, and \u201cexcessive preparation\u201d based on calculated cut\u2010off values. History of root canal re\u2010treatment (reRCT), and time from the primary root canal treatment (pRCT) were assessed as cumulative factors. Descriptive and logistic regression analyses were used to identify risk factors for VRF. Receiver operating characteristic curves were constructed, and the corresponding area under the curve (AUC) was used to determine the model as a diagnostic tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      \u201cExcessive\u201d category at both pericervical and apical dentine was more frequently observed in teeth with VRF (81.8%; 36\/44, 61.4%; 27\/44) than in the control group (65.2%; 60\/92, 10.9%; 10\/92). Residual apical dentine, tooth type, history of reRCT, and time from pRCT \u2265\u200915 years were significantly associated with VRF in the multiple binary logistic regression analyses (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Successful pRCT with minimum canal preparation, particularly at the apical level, is essential to minimize the likelihood of VRF. In ETMs with an isolated periodontal probing depth \u2265\u20095\u2009mm, assessing residual apical dentine, tooth type, reRCT history, and time since pRCT can effectively differentiate VRF from non\u2010VRF teeth (AUC, 0.940;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), offering valuable diagnostic guidance.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70293","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T20:20:22Z","timestamp":1770150022000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association Between Residual Pericervical and Apical Dentine and Vertical Root Fracture in Endodontically Treated Molars: A Case\u2010Control Study"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3718-167X","authenticated-orcid":false,"given":"Kwangsoon","family":"Lee","sequence":"first","affiliation":[{"name":"Practice Limited to Endodontics Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0614-6951","authenticated-orcid":false,"given":"Shanon","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Endodontology King's College London Dental Institute London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9898-6378","authenticated-orcid":false,"given":"Manjeet","family":"Ahlowalia","sequence":"additional","affiliation":[{"name":"Department of Endodontology King's College London Dental Institute London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6466-8059","authenticated-orcid":false,"given":"Ruth Perez","family":"Alfayate","sequence":"additional","affiliation":[{"name":"Department of Endodontics Universidad Europea de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6901-0280","authenticated-orcid":false,"given":"Federico","family":"Foschi","sequence":"additional","affiliation":[{"name":"Department of Endodontology UCL Eastman Dental Institute London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.12.002"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00563.x"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(99)70252-0"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2010.01.001"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.02.019"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200101000-00017"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-0707.124146"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.10.008"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2009.01632.x"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-020-03745-z"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.02.010"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/154411130301400103"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/etp.12089"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-4469.2004.00250.x"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2023.08.018"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200308000-00008"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2015.08.005"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12910"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/JCD.JCD_126_18"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-022-04564-0"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13737"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.14186"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(83)80150-2"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.04.012"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13134"},{"key":"e_1_2_14_27_1","unstructured":"Rivera E. 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