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The obturation sealers used were AH Plus, Endomethasone\u2010N, and Sealer Plus. Postoperative pain intensity was recorded by patients using a modified numerical rating scale (NRS) ranging from 0 (no pain) to 10 (severe pain).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No statistically significant differences in pain scores were found at 12, 24, or 48\u2009h in relation to gender, age, tooth position, pulpal diagnosis, type of sealer, or extrusion (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). The most common pain levels classified as uncomfortable were observed at 12 and 24\u2009h, while 94.1% of patients reported no pain at 48\u2009h; the remaining pain was mild. Pain scores decreased significantly after 48\u2009h for all variables.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Single\u2010session endodontic treatment with foraminal instrumentation showed a low incidence of postoperative pain that was not influenced by the variables analyzed in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Null Hypothesis<\/jats:title>\n                    <jats:p>The null hypothesis was that there was no association between the occurrence of postoperative pain and (i) age, (ii) patient gender, (iii) pulp diagnosis, (iv) tooth position, (v) endodontic sealer type, and (vi) sealer extrusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70313","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:52:28Z","timestamp":1772992348000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Postoperative Pain Frequency in Single\u2010Session Endodontic Treatments With Patency and Foraminal Enlargement"],"prefix":"10.1002","volume":"12","author":[{"given":"Viviane Barbosa","family":"Godoy","sequence":"first","affiliation":[{"name":"Department of Endodontics S\u00e3o Leopoldo Mandic School and Research Institute Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4633-720X","authenticated-orcid":false,"given":"Ana Grasiela","family":"Limoeiro","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Endodontics and Dental Materials Bauru School of Dentistry University of S\u00e3o Paulo (USP) Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Sandini","sequence":"additional","affiliation":[{"name":"University of Vale do Itaja\u00ed Itaja\u00ed Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4174-907X","authenticated-orcid":false,"given":"Vini","family":"Mehta","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry University of Ibn al\u2010Nafis for Medical Sciences Sana'a Yemen"},{"name":"Department of Dental Research Cell Dr. D. 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