{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:15:31Z","timestamp":1788279331337,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare the morphology and dimensions of the sella turcica in skeletal Class III malocclusion and cleft lip and palate (CLP) with Class I.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This comparative cross\u2010sectional study was conducted at the Armed Forces Institute of Dentistry, Rawalpindi, Pakistan, and involved 540 cases (Class I, Class III malocclusion, and CLP) using a non\u2010probability consecutive sampling method. The study included patients aged 12\u201350 years with Class I or Class III malocclusion or cleft palate while excluding those with previous orthodontic treatment or craniofacial syndromes. Data were collected from digital lateral cephalograms and patient records. The dimensions and morphology of the sella turcica were recorded. The Kruskal\u2013Wallis rank sum test, Dunn's test, chi\u2010square exact test, and linear regression were applied to analyze the relationship between sella turcica dimensions and malocclusion types.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sella turcica morphology differed significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with normal morphology most common in Class I (58.33%) and Class III (40.00%), while oblique anterior wall predominated in CLP (30.00%). Sella turcica dimensions also varied significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with Class I showing the largest median length (9.0\u2009mm), depth (9.0\u2009mm), and diameter (11.0\u2009mm), followed by Class III, and the smallest values in CLP. Post hoc tests confirmed that Classes I and III had significantly greater dimensions than CLP (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Regression analysis indicated that CLP had significantly smaller length (\u22121.48\u2009mm), depth (\u22121.23\u2009mm), and diameter (\u22121.75\u2009mm) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), while Class III showed reduced length and diameter. Males had slightly greater length and diameter, whereas age showed no significant effect.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Class III and CLP had smaller sella turcica dimensions and more irregular shapes than Class I, suggesting that monitoring their size and shape could help identify developmental issues early for better diagnosis and treatment planning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70322","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:37:25Z","timestamp":1773013045000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Evaluation of Sella Turcica Morphology and Dimensions in Skeletal Class III Malocclusion and Cleft Lip and Palate Patients Versus Class I Individuals"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9510-8200","authenticated-orcid":false,"given":"Bushra","family":"Gul","sequence":"first","affiliation":[{"name":"Armed Forces Institute of Dentistry Rawalpindi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erum","family":"Amin","sequence":"additional","affiliation":[{"name":"Orthodontics Armed Forces Institute of Dentistry\/National University of Medical Sciences (NUMS) Rawalpindi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8100-561X","authenticated-orcid":false,"given":"Umar","family":"Hussain","sequence":"additional","affiliation":[{"name":"Orthodontics Saidu College of Dentistry Swat Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faiza","family":"Malik","sequence":"additional","affiliation":[{"name":"Sharif Medical &amp; Dental College Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0629-800X","authenticated-orcid":false,"given":"Rana","family":"Faiza","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Sharif Medical and Dental College Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundus Saad","family":"Alqarni","sequence":"additional","affiliation":[{"name":"College of Dentistry King Khalid University Abha Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4556-1995","authenticated-orcid":false,"given":"Waqas","family":"Naseem","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University of Debrecen Debrecen Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,1]]},"reference":[{"issue":"2","key":"e_1_2_11_2_1","first-page":"172","article-title":"Association Between Variations in Sella Turcica Dimensions and Morphology and Skeletal Malocclusions","volume":"31","author":"Afzal E.","year":"2019","journal-title":"Journal of Ayub Medical College, Abbottabad: JAMC"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-020-02481-z"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/2177-6709.23.6.40.e1-10.onl"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjm049"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1597\/07-058.1"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12380"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/26.6.613"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/26.6.597"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2024.152233"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2021.05.017"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.2319\/032717-218.1"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4625-45.2.12"},{"issue":"3","key":"e_1_2_11_14_1","first-page":"229","article-title":"A Cephalometric Study of Sella Turcica: Correlation of Its Size With Different Skeletal Malocclusions","volume":"16","author":"Grover N.","year":"2023","journal-title":"International Journal of Clinical Pediatric Dentistry"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2001.0088"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18094456"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1055665620954058"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.5603\/FM.a2018.0022"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/14653125.2016.1201302"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13193088"},{"issue":"9","key":"e_1_2_11_21_1","article-title":"The Comparative Evaluation of the Morphology and Dimensions of the Sella Turcica in Skeletal Class III Patients and Patients With Unilateral Cleft Lip and Palate in Post\u2010Pubertal Age Group","volume":"14","author":"Nerurkar S.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/03015742251386953"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.15644\/asc58\/2\/6"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12426"},{"issue":"5","key":"e_1_2_11_25_1","first-page":"571","article-title":"Sella Turcica\u2014Its Importance in Orthodontics and Craniofacial Morphology","volume":"10","author":"Sathyanarayana H. P.","year":"2013","journal-title":"Dental Research Journal"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-024-00785-z"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ortho.2024.100939"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-018-0499-1"},{"key":"e_1_2_11_29_1","article-title":"Cephalometric Assessment of Sella Turcica Morphology and Dimensions in Patients With Non\u2010Syndromic Cleft Lip and Palate: A Systematic Review and Meta\u2010Analysis","author":"Siddiqui H. P.","year":"2025","journal-title":"Cleft Palate Craniofacial Journal"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-019-02406-5"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tria.2019.100054"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000009806"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1597\/13-258"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-55916-y"},{"issue":"3","key":"e_1_2_11_35_1","article-title":"Correlation of Shape and Size of Sella Turcica With the Type of Facial Skeletal Class in an Iranian Group","volume":"12","author":"Valizadeh S.","year":"2015","journal-title":"Iranian Journal of Radiology"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-6343.2010.01485.x"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13152510"}],"container-title":["Clinical and Experimental Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.70322","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cre2.70322","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.70322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T15:18:33Z","timestamp":1788275913000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cre2.70322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,1]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/cre2.70322"],"URL":"https:\/\/doi.org\/10.1002\/cre2.70322","archive":["Portico"],"relation":{},"ISSN":["2057-4347","2057-4347"],"issn-type":[{"value":"2057-4347","type":"print"},{"value":"2057-4347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,1]]},"assertion":[{"value":"2025-12-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70322"}}