{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:15:26Z","timestamp":1788279326849,"version":"build-2803163510"},"reference-count":74,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Vertical root fractures (VRFs) pose significant clinical challenges and may result in tooth loss. Current diagnostic methods, including conventional radiography and CBCT, are challenging to detect VRFs, especially in the early stages. Optical coherence tomography (OCT) has recently been introduced as a non\u2010invasive imaging technique for dental diagnostics. However, current knowledge of OCT in endodontics requires further research. This Article will review current literature on OCT and evaluate its potential as a diagnostic tool for VRFs in endodontics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive scoping review was conducted using electronic databases including PubMed, Scopus, Ebsco, Google Scholars, and Embase without any language restrictions up to January 2025, focusing on OCT applications in diagnosing cracks and VRFs. Google and Open\u2010Grey were used to search for grey literature alongside handsearching. Clinical and laboratory\u2010based studies conducted on adult human\u2010teeth were considered eligible. A total of 28,303 studies were generated when screened in the last 20 years; 27,887 studies were found relevant, and 416 duplicates were removed. Following title and abstract screening, a total of 36 studies were considered for full\u2010text review. Ten studies met the inclusion criteria and were included in this review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>OCT system demonstrated high specificity (63%\u2013100%) and sensitivity (83%\u201398%) in detecting cracks and VRFs. SS\u2010OCT demonstrated promising imaging capabilities and deep penetration. OCT offers advantages over radiographs and CBCT in non\u2010radiation exposure and real\u2010time imaging. OCT systems could be considered in clinical practice following improvements in relation to penetration depth and intra\u2010oral adaptation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Within the limitation of this scoping review, the use of OCT is promising for detection of cracks and VRFs. By addressing the limitations related to penetration depth, mechanical design, and soft tissue imaging, OCT may find its path into clinical adoption, including endodontics. Areas that can help includes developing OCT systems tailored for routine endodontic use and assessing long\u2010term impacts in the field.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70323","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T19:49:28Z","timestamp":1773085768000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optical Coherence Tomography for Detection of Dental Cracks and Vertical Root Fracture: A Scoping Review"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3432-7025","authenticated-orcid":false,"given":"MHD. Mouaffak","family":"Alkhani","sequence":"first","affiliation":[{"name":"Department of Oral Research, School of Dentistry University of Alabama at Birmingham  Birmingham Alabama USA"},{"name":"Department of Advanced Education in General Dentistry, School of Dentistry Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Yasser","family":"Albittar","sequence":"additional","affiliation":[{"name":"Jacksonville University School of Orthodontics  Jacksonville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uzma Munawwar","family":"Shaikh","sequence":"additional","affiliation":[{"name":"Maharashtra University of Health Sciences  Nashik India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Takriti","sequence":"additional","affiliation":[{"name":"Department of Periodontics, School of Dentistry University of Illinois Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8775-3950","authenticated-orcid":false,"given":"Aylin","family":"Baysan","sequence":"additional","affiliation":[{"name":"Centre for Oral Bioengineering, Barts and the London Faculty of Medicine and Dentistry Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-012-1208-y"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-65169-5_4"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2020.10.012"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.06.019"},{"key":"e_1_2_11_6_1","volume-title":"In Vitro Evaluation of Optical Coherence Tomography and Ultrasound Probes Used in the Detection of Intact Dentin and Various Anomalies Within Root Canals","author":"Birsch R. 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