{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:15:31Z","timestamp":1788279331784,"version":"build-2803163510"},"reference-count":52,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to evaluate the association between malocclusion severity and oral health\u2010related quality of life (OHRQoL) in children aged 11\u201314 years by simultaneously using the Child Perceptions Questionnaire (CPQ11\u201014), Parent\/Caregiver Perceptions Questionnaire (P\u2010CPQ), and Dental Aesthetic Index (DAI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      This analytical cross\u2010sectional, clinic\u2010based study was conducted on 117 children aged 11\u201314 years and their parents\/guardians referred to a specialized dental clinic in Rasht city, Iran, in 2022. Children with systemic diseases, a history of orthodontic treatment, or craniofacial abnormalities were excluded. OHRQoL was independently assessed using the CPQ11\u201014 and P\u2010CPQ. Malocclusion severity was determined using the DAI, and children were categorized into normal occlusion, definite, severe, and very severe malocclusion groups. The associations of age and gender with OHRQoL were also examined. Data were analyzed statistically (\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u2009=\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean OHRQoL score was significantly higher among children with malocclusion compared with those with normal occlusion (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), indicating poorer quality of life. Higher malocclusion severity was significantly associated with worse OHRQoL scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). These associations were significant in both sexes (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). A significant association between malocclusion severity and poorer OHRQoL was observed in children older than 12 years (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), whereas this association was not statistically significant in children aged 12 years or younger (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Multivariable analysis confirmed that malocclusion severity remained independently associated with OHRQoL after adjustment for demographic factors (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Greater severity of malocclusion, particularly in older children, is significantly associated with poorer OHRQoL. The relative agreement between child and parent assessments highlights the importance of considering both perspectives in clinical and research settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70337","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T09:11:53Z","timestamp":1774516313000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association Between Malocclusion Severity and Oral Health\u2010Related Quality of Life in Children Aged 11\u201314 Years Using CPQ11\u201014 and P\u2010CPQ"],"prefix":"10.1002","volume":"12","author":[{"given":"Seyedeh Hediyeh","family":"Daneshvar","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Dental Sciences Research Center, School of Dentistry Guilan University of Medical Sciences Rasht Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Negin","family":"Bazgir","sequence":"additional","affiliation":[{"name":"School of Dentistry Guilan University of Medical Sciences Rasht Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sobhan","family":"Agheshteh Sabzevar","sequence":"additional","affiliation":[{"name":"Student Research Committee, School of Dentistry Guilan University of Medical Sciences Rasht Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6739-9971","authenticated-orcid":false,"given":"Yasamin","family":"Babaee Hemmati","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Dental Sciences Research Center, School of Dentistry Guilan University of Medical Sciences Rasht Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.2319\/092214-681.1"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/jioh.jioh_172_20"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7920973"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-025-05650-x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"crossref","unstructured":"Baskaradoss J. andP.Bhagavatula. 2021.Measurement and Distribution of Malocclusion Trauma and Congenital Anomalies 208\u2013217. 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R.Bucci V.D'Ant\u00f2 S.Cascella R.Rongo andR.Valletta. 2025. \u201cParental Perceptions and Family Impact on Adolescents' Oral Health\u2010Related Quality of Life in Relation to the Severity of Malocclusion and Caries Status.\u201dChildren12 no. 4 (March): 425.","DOI":"10.3390\/children12040425"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/ejd.ejd_61_17"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.2319\/012713-83.1"},{"issue":"2","key":"e_1_2_13_14_1","first-page":"127","article-title":"Oral Health\u2010Related Quality\u2010Of\u2010Life Among Children in Swedish Dental Care: The Impact From Malocclusions or Orthodontic Treatment Need","volume":"74","author":"Dimberg L.","year":"2016","journal-title":"Acta Odontologica Scandinavica"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-025-00580-3"},{"issue":"2","key":"e_1_2_13_16_1","first-page":"178","article-title":"Prevalence of Malocclusion in Permanent Dentition of Iranian Population: A Review Article","volume":"47","author":"Eslamipour F.","year":"2018","journal-title":"Iranian Journal of Public Health"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/idj.12009"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.81741"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjad009"},{"issue":"3","key":"e_1_2_13_20_1","first-page":"229","article-title":"Do Malocclusions Affect the Oral Health\u2010Related Quality of Life?","volume":"9","author":"Heravi F.","year":"2011","journal-title":"Oral Health & Preventive Dentistry"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-024-05069-w"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12693"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910208100705"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-018-0482-x"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-018-0701-5"},{"issue":"3","key":"e_1_2_13_26_1","first-page":"1","article-title":"Malocclusion's Risk Factors: A Systematic Review","volume":"12","author":"Kenza K.","year":"2025","journal-title":"Open Access Library Journal"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.21859\/jech.5.1.27"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjaa028"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-015-1681-3"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1051\/orthodfr\/2018011"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2006.00324.x"},{"issue":"2","key":"e_1_2_13_32_1","first-page":"115","article-title":"Worldwide Prevalence of Malocclusion in the Different Stages of Dentition: A Systematic Review and Meta\u2010Analysis","volume":"21","author":"Lombardo G.","year":"2020","journal-title":"European Journal of Paediatric Dentistry"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.771"},{"issue":"3","key":"e_1_2_13_34_1","first-page":"7","article-title":"The Effect of Three Different Malocclusions on the Quality of Life of 12 to 14 Years Old Students in Rasht in 2019","volume":"9","author":"Masoumi F. 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A.Janeshin F.Gholinia R. F.Alinejad andD.MalekiThe Prevalence of Malocclusion and Dental Caries in 11\u2010to 14\u2010Year\u2010Old Children in Roudsar Iran.2019."},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-03187-5"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.54393\/pjhs.v5i08.2027"}],"container-title":["Clinical and Experimental Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.70337","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cre2.70337","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cre2.70337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T15:18:43Z","timestamp":1788275923000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cre2.70337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,26]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/cre2.70337"],"URL":"https:\/\/doi.org\/10.1002\/cre2.70337","archive":["Portico"],"relation":{},"ISSN":["2057-4347","2057-4347"],"issn-type":[{"value":"2057-4347","type":"print"},{"value":"2057-4347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,26]]},"assertion":[{"value":"2025-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70337"}}