{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:54:24Z","timestamp":1791294864950,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005716","name":"Babol University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005716","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      The long\u2010term esthetic performance of CAD\/CAM ceramic restorations may be influenced by repeated exposure to therapeutic mouthrinses. This study evaluated the effects of chlorhexidine, essential oil\u2010based, and stannous fluoride mouthrinses on the color stability (\u0394\n                      <jats:italic>E<\/jats:italic>\n                      ) and surface roughness (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sub>a<\/jats:sub>\n                      ) of glazed and polished CAD\/CAM ceramics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      In this in vitro experimental study, 320 specimens fabricated from four CAD\/CAM ceramic materials (Vita Mark II, IPS e.max CAD, CAD, Celtra Duo, and high\u2010translucency zirconia) were randomly assigned to glazed or polished surface treatment groups and immersed daily for 20\u2009min in chlorhexidine, essential oil\u2010based, stannous fluoride mouthrinses, or distilled water (control) for 30 days. Color stability was assessed using spectrophotometry based on the CIE Lab* color system, and surface roughness was measured using laser profilometry. Data were analyzed using one\u2010way ANOVA followed by Tukey's post hoc test (\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u2009=\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The effects of therapeutic mouthrinses on color stability and surface roughness varied according to ceramic material and surface finish. The greatest color change was observed in polished IPS e.max CAD immersed in the essential oil\u2010based mouthrinse (\u0394\n                      <jats:italic>E<\/jats:italic>\n                      \u2009=\u20093.69), whereas the lowest \u0394\n                      <jats:italic>E<\/jats:italic>\n                      was recorded for glazed Celtra Duo immersed in stannous fluoride (\u0394\n                      <jats:italic>E<\/jats:italic>\n                      \u2009=\u20091.59). Polished specimens consistently exhibited greater increases in surface roughness than glazed specimens across all ceramic materials. Significant differences in \u0394\n                      <jats:italic>E<\/jats:italic>\n                      and\/or\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sub>a<\/jats:sub>\n                      were identified according to ceramic type, mouthrinse composition, and surface finish (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The effects of therapeutic mouthrinses on CAD\/CAM ceramics depend on both ceramic composition and surface finish. Essential oil\u2010based mouthrinse produced the greatest color changes in several ceramic materials, whereas glazed surfaces generally demonstrated greater resistance to surface roughness changes than polished surfaces. These findings highlight the importance of considering both material selection and surface finishing when recommending therapeutic mouthrinse use for patients with CAD\/CAM ceramic restorations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70469","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:52:46Z","timestamp":1791291166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effects of Chlorhexidine, Essential Oil\u2010Based, and Stannous Fluoride Mouthrinses on the Color Stability and Surface Roughness of CAD\/CAM Ceramics"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1418-8959","authenticated-orcid":false,"given":"Fateme","family":"Ghasemian Gorji","sequence":"first","affiliation":[{"name":"Student Research Committee Babol University of Medical Sciences Babol I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6883-5336","authenticated-orcid":false,"given":"Fariba","family":"Ezoji","sequence":"additional","affiliation":[{"name":"Dental Materials Research Center, Health Research Institute Babol University of Medical Sciences Babol I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3718-3870","authenticated-orcid":false,"given":"Ghazaleh","family":"Ahmadizenouz","sequence":"additional","affiliation":[{"name":"Oral Health Research Center, Health Research Institute Babol University of Medical Sciences Babol I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3841-0609","authenticated-orcid":false,"given":"Seyedali","family":"Seyedmajidi","sequence":"additional","affiliation":[{"name":"Dental Materials Research Center, Health Research Institute Babol University of Medical Sciences Babol I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"issue":"1","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.prosdent.2015.06.014","article-title":"Color Stainability of CAD\/CAM and Nanocomposite Resin Materials","volume":"115","author":"Acar O.","year":"2016","journal-title":"Journal of Prosthetic Dentistry"},{"key":"e_1_2_11_3_1","first-page":"336","article-title":"Effect of Various Commercially Available Mouthwashes on Color Stability of IPS Empress Ceramic Restoration: An In\u2010vitro Study","volume":"18","author":"Alkhudair L.","year":"2022","journal-title":"Esculapio"},{"issue":"2","key":"e_1_2_11_4_1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.prosdent.2017.10.024","article-title":"Effect of Surface Treatments and Coffee Thermocycling on the Color and Translucency of CAD\u2010CAM Monolithic Glass\u2010Ceramic","volume":"120","author":"Alp G.","year":"2018","journal-title":"Journal of Prosthetic Dentistry"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2021.06.002"},{"issue":"4","key":"e_1_2_11_6_1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/S0109-5641(97)80038-3","article-title":"Comparison of Surface Roughness of Oral Hard Materials to the Threshold Surface Roughness for Bacterial Plaque Retention: A Review of the Literature","volume":"13","author":"Bollenl C. 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