{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:55:35Z","timestamp":1791294935270,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Management of the palatal donor site following periodontal plastic surgery remains challenging because of postoperative pain, bleeding, and patient discomfort. This study aimed to evaluate the efficacy of a chairside\u2010fabricated composite barrier in reducing morbidity at the palatal donor site.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In this randomized, parallel\u2010group clinical trial, 50 patients undergoing soft tissue augmentation were allocated to either a test group (composite barrier + collagen sponge) or a control group (collagen sponge alone). Intraoperative measurements included palatal tissue thickness, graft dimensions, and donor site management time. Postoperative outcomes (pain, bleeding, discomfort, chewing difficulty, stress, analgesic consumption, and willingness for retreatment) were assessed at prespecified time points during the first 2 postoperative weeks. Donor sites complications were specifically assessed on postoperative day 7.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All participants completed the study without dropouts. Compared with controls, the composite barrier group required significantly shorter wound management time (210.42\u2009\u00b1\u200952.04 vs. 445.76\u2009\u00b1\u200977.43\u2009s;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and lower analgesic consumption during the first week (1328.00\u2009\u00b1\u2009846.33 vs. 4160.00\u2009\u00b1\u20091366.26\u2009mg;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Pain scores were significantly lower in the composite barrier group on postoperative days 1\u20137 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), slightly higher on day 10 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007), and similar on day 14. Bleeding scores were lower during the first 4 postoperative days (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Patient\u2010reported discomfort, chewing difficulty, and stress were significantly reduced in the composite barrier group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), which also showed greater willingness for retreatment (7.80\u2009\u00b1\u20091.15 vs. 2.04\u2009\u00b1\u20091.34;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). No necrosis, infection, or hematoma occurred.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Application of a composite barrier for palatal donor site management reduces the time required to achieve intraoperative hemostasis and is associated with lower postoperative pain, bleeding, and patient discomfort. This approach may improve patient\u2010reported outcomes following periodontal plastic surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>This project was registered in the Iranian Registry of Clinical Trials under the ID (IRCT20250513065721N2), and the registration date was 21\/6\/2025.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70470","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:00:21Z","timestamp":1791291621000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Peripheral Seal Composite Barrier (PSCB) for Management of Palatal Donor Sites in Mucogingival Surgery: A Randomized Clinical Trial"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5827-861X","authenticated-orcid":false,"given":"Moein","family":"Khojaste","sequence":"first","affiliation":[{"name":"Department of Periodontics, School of Dentistry Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2569-4518","authenticated-orcid":false,"given":"Farid","family":"Shiezadeh","sequence":"additional","affiliation":[{"name":"Dental Research Center Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0515-4252","authenticated-orcid":false,"given":"Zahra","family":"Moslehitabar","sequence":"additional","affiliation":[{"name":"Department of Periodontics, School of Dentistry Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"issue":"6","key":"e_1_2_14_2_1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s00784-024-05733-z","article-title":"Performance of Multiple Therapeutic Approaches for Palatal Wound Healing After Soft Tissue Graft Removal\u2014An Overview of Systematic Reviews","volume":"28","author":"Almeida M. C. L.","year":"2024","journal-title":"Clinical Oral Investigations"},{"issue":"1","key":"e_1_2_14_3_1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/JPER.22-0172","article-title":"Patient\u2010Reported Outcomes of Palatal Donor Site Healing Using Four Different Wound Dressing Modalities Following Free Epithelialized Mucosal Grafts: A Four\u2010Arm Randomized Controlled Clinical Trial","volume":"94","author":"Basma H. 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