{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:54:59Z","timestamp":1791294899353,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study is to synthesize evidence on hantavirus transmission and occupational exposure pathways relevant to dentistry, and to propose an evidence\u2010informed tiered infection prevention and control (IPC) framework that distinguishes established from theoretical risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>The initial narrative search covered database inception through May 15, 2026 in MEDLINE\/PubMed, Embase, Web of Science, Scopus, Google Scholar, and WHO\/CDC\/ECDC\/OSHA sources, followed by a targeted PubMed\/MEDLINE and public\u2010health guidance update through August 18, 2026. Approximately 1450 records were identified. After duplicate removal, 1070 records were subjected to title\/abstract screening, 215 full\u2010text records were assessed for eligibility, and 45 sources were included in the final synthesis, comprising 34 peer\u2010reviewed publications and 11 gray\u2010literature or public\u2010health guidance sources.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Environmental exposure to infected\u2010rodent contamination is the established occupational pathway. Limited person\u2010to\u2010person transmission is documented for the Andes virus (ANDV), but no dental transmission has been reported. ANDV RNA and culture\u2010based infectivity have been demonstrated in some oral\/respiratory fluids; however, dental\u2010aerosol transmission has not been shown. Dental\u2010specific occupational risk therefore remains unquantified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>No dental transmission has been documented, and patient\u2010related risk remains uncertain. Standard precautions and rodent control are foundational; suspected or confirmed ANDV warrants transmission\u2010based precautions and airborne precautions for aerosol\u2010generating procedures according to current guidance. The proposed dental tiers are evidence\u2010informed, author\u2010derived, and unvalidated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cre2.70481","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:05:23Z","timestamp":1791291923000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hantavirus in Dentistry: Occupational Exposure Considerations and a Proposed Tiered Infection Prevention and Control Framework\u2014A Narrative Review"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7257-5477","authenticated-orcid":false,"given":"Parsa","family":"Vafaei","sequence":"first","affiliation":[{"name":"Faculty of Dentistry Azad University of Isfahan (Khorasgan Branch) Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1715-0198","authenticated-orcid":false,"given":"Morteza","family":"Banakar","sequence":"additional","affiliation":[{"name":"Centre of Molecular Medicine and Diagnostics (COMManD), Saveetha Dental College &amp; Hospitals, Saveetha Institute of Medical and Technical Sciences Saveetha University Chennai India"},{"name":"Department of Medical Biotechnology Shahid Sadoughi University of Medical Sciences Yazd Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa","family":"Alam","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, School of Dentistry Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Javad","family":"Askari","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics Faculty of Dentistry, Isfahan University of Medical Sciences Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9436-9375","authenticated-orcid":false,"given":"Mohsen","family":"Golkar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, School of Dentistry Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"key":"e_1_2_20_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.identj.2024.09.026"},{"key":"e_1_2_20_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2606496"},{"key":"e_1_2_20_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/31.1.189"},{"key":"e_1_2_20_5_1","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.001975"},{"key":"e_1_2_20_6_1","doi-asserted-by":"crossref","unstructured":"Castillo C. J.Mardones andE.Villagra(2000). Prevalence of Anti\u2010hantavirus Antibodies in Health Care Personnel in Direct Contact With Patients With HPS in Temuco Chile 1997\u20131999. Revista Medica de Chile 128(7) 735\u2013739.https:\/\/doi.org\/10.4067\/s0034-98872000000700005.","DOI":"10.4067\/S0034-98872000000700005"},{"key":"e_1_2_20_7_1","unstructured":"Centers for Disease Control and Prevention. (2026 May 8). 2026 Multi\u2010Country Hantavirus Cluster Linked to Cruise Ship (Health Alert Network CDCHAN\u201000528).https:\/\/www.cdc.gov\/han\/php\/notices\/han00528.html."},{"key":"e_1_2_20_8_1","unstructured":"Centers for Disease Control and Prevention (CDC).2026a. Interim Guidance for Public Health Assessment and Management of People With Potential Exposure to Andes Virus.CDC May 14.https:\/\/www.cdc.gov\/hantavirus\/php\/emergency-guidance\/index.html."},{"key":"e_1_2_20_9_1","unstructured":"Centers for Disease Control and Prevention. (n.d.). Hantavirus Prevention\u2014Rodent Control Guidance. CDC. 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