{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:51:19Z","timestamp":1759564279101,"version":"3.37.3"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this current survey was to assess both the occurrence and severity of pre\u2010 and post\u2010endodontic pain among female individuals, distinguishing between those with anemia and those without.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In the current study, we included a total of 60 women with anemia (hemoglobin &lt; 11) and those without anemia (hemoglobin &gt; 13). We recorded the occurrence and severity of pain before and at 24, 48, and 72\u2009h following root canal treatment using a visual analog scale (VAS)\u00a0ranging from 0 to 10. Additionally, we collected data on patient age, tooth type, as well as pulpal and periapical conditions. Statistical analysis was carried out using two\u2010way ANOVA, pairedt\u2010tests, and Pearson correlation coefficient. The significance level for statistical tests was set at <jats:italic>p<\/jats:italic>\u2009\u2264\u2009.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of preoperative pain in both anemic and non\u2010anemic patients was 80%. The total incidence of post\u2010operative pain was recorded as 71.7% (82.2% in anemic and 61.1% in non\u2010anemic women). Compared with the pretreatment pain incidence and intensity, the values increased in 24\u2009h but declined in 48 h\u00a0and 72\u2009h after treatment. Considering the posttreatment pain intensity, the mean values were higher in the three time intervals (24, 48, and 72\u2009h) in anemic patients. Pulpal and periapical status, in contrast to age and tooth type, significantly contributed to the intensity of posttreatment pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Regarding the importance of pain phenomenon in human life, it is recommended to consider anemia as an important risk factor for post\u2010endodontic pain. Early diagnosis and analgesic treatment interventions in anemic females, alongside the pain control during root canal treatment, could promote the patient's satisfaction and quality of care.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.799","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T03:32:45Z","timestamp":1697599965000},"page":"1122-1128","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessing the occurrence and severity of pre\u2010 and postendodontic pain in anemic and healthy female patients"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3543-9537","authenticated-orcid":false,"given":"Maryam","family":"Kazemipoor","sequence":"first","affiliation":[{"name":"Department of Endodontics, School of Dentistry Shahid Sadoughi University of Medical Sciences Yazd 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