{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T17:54:57Z","timestamp":1779040497492,"version":"3.51.4"},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp;amp; Exp Dental Res"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to clarify the relationship between oral frailty and oral dysbiosis among hospitalized patients aged\u2009\u2265\u200950 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective observational study was conducted. Number of teeth, masticatory ability, articulatory oral motor skill, tongue pressure, swallowing pressure, and choking were used to assess oral frailty. Saliva samples were collected from the oral cavity for bacterial culture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total 103 in patients enrolled and 53.4% suffered from oral frailty. Oral frailty was found to have a 3.07\u2010fold correlation with the presence of <jats:italic>Enterobacterales<\/jats:italic> in the oral cavity (<jats:italic>p<\/jats:italic>\u2009=\u20090.037), especially in poor articulatory oral motor skill, which showed at greater risk of <jats:italic>Enterobacterales<\/jats:italic> isolated from the oral cavity by 5.58\u2010fold (<jats:italic>p<\/jats:italic>\u2009=\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Half of hospitalized patients was found to have oral frailty that was related to more <jats:italic>Enterobacterales<\/jats:italic> in the oral cavity. This evidence suggests that the enhancement of articulatory oral motor skills may serve as a potential strategy for mitigating the presence of Enterobacterales within the oral cavity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cre2.890","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T04:45:23Z","timestamp":1717130723000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The relationship between oral frailty and oral dysbiosis among hospitalized patients aged older than 50 years"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7353-3383","authenticated-orcid":false,"given":"Yen\u2010Chin","family":"Chen","sequence":"first","affiliation":[{"name":"College of Medicine National Sun Yat\u2010sen University Kaohsiung Taiwan"},{"name":"Department of Nursing, College of Medicine National Cheng Kung University Tainan 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