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Under the applied reaction conditions, catalytic transfer hydrogenation and hydrogenation with molecular H<jats:sub>2<\/jats:sub> were effective at producing high yields of \u03b3\u2010valerolactone. However, the conversion of this stable intermediate to MTHF required the combination of both hydrogen sources (the solvent and the H<jats:sub>2<\/jats:sub> atmosphere) to achieve good yields. The reaction system with 2\u2010propanol as solvent and Ni\u2013Cu\/Al<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub> as catalyst allowed full conversion of LA and a MTHF yield of 80\u2009% after 20\u2005h reaction time at 250\u2009\u00b0C and 40\u2005bar of H<jats:sub>2<\/jats:sub> (at room temperature). The system showed the same catalytic activity at LA feed concentrations of 5 and up to 30\u2005wt%, and also when high acetone concentration at the beginning of the reaction were added, which confirmed the potential industrial applications of this solvent\/catalyst system.<\/jats:p>","DOI":"10.1002\/cssc.201600751","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T10:36:25Z","timestamp":1470220585000},"page":"2488-2495","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["The Role of the Hydrogen Source on the Selective Production of \u03b3\u2010Valerolactone and 2\u2010Methyltetrahydrofuran from Levulinic Acid"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9577-1187","authenticated-orcid":false,"given":"Iker","family":"Obreg\u00f3n","sequence":"first","affiliation":[{"name":"Chemical and Environmental Engineering Department University of the Basque Country (UPV\/EHU), Alameda Urquijo s\/n  48013 Bilbao Spain"},{"name":"Chair for Heterogeneous Catalysis and Chemical Technology, Institut f\u00fcr Technische und Makromolekulare Chemie, RWTH Aachen University, Worringerweg 1  D-52074 Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4082-5352","authenticated-orcid":false,"given":"Inaki","family":"Gandarias","sequence":"additional","affiliation":[{"name":"Chemical and Environmental Engineering Department University of the Basque Country (UPV\/EHU), Alameda Urquijo s\/n  48013 Bilbao Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad G.","family":"Al\u2010Shaal","sequence":"additional","affiliation":[{"name":"Chair for Heterogeneous Catalysis and Chemical Technology, Institut f\u00fcr Technische und Makromolekulare Chemie, RWTH Aachen University, Worringerweg 1  D-52074 Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mevissen","sequence":"additional","affiliation":[{"name":"Chair for Heterogeneous Catalysis and Chemical Technology, Institut f\u00fcr Technische und Makromolekulare Chemie, RWTH Aachen University, Worringerweg 1  D-52074 Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro L.","family":"Arias","sequence":"additional","affiliation":[{"name":"Chemical and Environmental Engineering Department University of the Basque Country (UPV\/EHU), Alameda Urquijo s\/n  48013 Bilbao Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4970-2957","authenticated-orcid":false,"given":"Regina","family":"Palkovits","sequence":"additional","affiliation":[{"name":"Chair for Heterogeneous Catalysis and Chemical Technology, Institut f\u00fcr Technische und Makromolekulare Chemie, RWTH Aachen University, Worringerweg 1  D-52074 Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,2]]},"reference":[{"key":"e_1_2_2_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cattod.2008.04.017"},{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr068360d"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-chembioeng-073009-100935"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/b605036k"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr050989d"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC04401K"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/c3gc41492b"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/b922014c"},{"key":"e_1_2_2_9_1","unstructured":"S. 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