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This work is distinct in that a detailed mechanistic analysis of the reaction pathways of veratrylglycero\u2010\u03b2\u2010guaiacyl ether (VGE) catalyzed by transition\u2010metal\u2010free solid acid zeolite in aqueous conditions at high hydrogen pressure has been performed. VGE degradation produced high monomers yields (\u224887\u2009%), including guaiacol (48.2\u2009%), 1\u2010(3,4\u2010dimethoxyphenyl)ethanol (10.3\u2009%), 1\u2010(3,4\u2010dimethoxyphenyl)\u20102\u2010propanol (6.1\u2009%), 3,4\u2010dimethoxyphenylpropanol (4.7\u2009%), 3,4\u2010dimethoxycinnamyl alcohol (4.1\u2009%), and 1,2\u2010dimethoxy\u20104\u2010propylbenzene (2\u2009%). The products were identified and confirmed by the in\u2005situ solid\u2010state magic angle spinning (MAS) <jats:sup>13<\/jats:sup>C\u2005NMR spectroscopy in real\u2010time conditions and the two\u2010dimensional gas chromatography (GC\u00d7GC). A variety of products reveal the crucial role of hydrogen, water, and acid sites for heterolytic cleavage of the \u03b2\u2010O\u20104 bond in VGE. Decarbonylation, hydrogenolysis, hydrogenation, and dehydration reaction pathways are proposed and further validated using first\u2010principles calculations.<\/jats:p>","DOI":"10.1002\/cssc.202202001","type":"journal-article","created":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T02:28:45Z","timestamp":1671244125000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Elucidating the Reaction Pathways of Veratrylglycero\u2010\u03b2\u2010Guaiacyl Ether Degradation over Metal\u2010Free Solid Acid Catalyst with Hydrogen**"],"prefix":"10.1002","volume":"16","author":[{"given":"Hao","family":"Ruan","sequence":"first","affiliation":[{"name":"Bioproducts Sciences and Engineering Laboratory Department of Biological Systems Engineering Washington State University  Richland Washington 99354 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