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The reaction is performed in water\/methanol solution in a simple undivided cell using sulfuric acid\u2010treated graphite electrodes with industrially feasible current densities between 300 and 350\u2009mA\u2009cm<jats:sup>\u22122<\/jats:sup>. Other components of the reaction are sodium chloride which is used as a supporting electrolyte and tributylmethylammonium chloride which raises the current efficiency. With a slight modification in the reaction temperature and current density, the outcome can be tuned from high current efficiency toward higher chemical yields. The conditions of the batch reaction are successfully transferred to a continuous flow\u2010cell arrangement. Mechanistic studies indicate the involvement of hydroxymethyl radicals in the electrolysis, and deuterium\u2010labeling experiments show the partial conversion of methanol into formaldehyde and ethylene glycol.<\/jats:p>","DOI":"10.1002\/cssc.202500123","type":"journal-article","created":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T08:44:33Z","timestamp":1743151473000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["TEMPO\u2010Mediated Paired Electrosynthesis of Ethylene Glycol from Formaldehyde and Methanol at High Current Densities"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6905-1920","authenticated-orcid":false,"given":"Valtteri","family":"Oksanen","sequence":"first","affiliation":[{"name":"Chemical and Polymer Synthesis VTT Technical Research Centre of Finland Ltd.,  Box 1000 FI\u201002044 Espoo Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiia","family":"Malinen","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering Aalto University  Box 11000 FI\u201000076 Aalto Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8874-5012","authenticated-orcid":false,"given":"Tao","family":"Hu","sequence":"additional","affiliation":[{"name":"Research Unit of Sustainable Chemistry University of Oulu  Box 4300 FI\u201090014 Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7097-1983","authenticated-orcid":false,"given":"Alexander","family":"Reznichenko","sequence":"additional","affiliation":[{"name":"Chemical and Polymer Synthesis VTT Technical Research Centre of Finland Ltd.,  Box 1000 FI\u201002044 Espoo Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0810-2971","authenticated-orcid":false,"given":"Tom","family":"Wirtanen","sequence":"additional","affiliation":[{"name":"Chemical and Polymer Synthesis VTT Technical Research Centre of Finland Ltd.,  Box 1000 FI\u201002044 Espoo Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","unstructured":"S.Rebsdat D.Mayer Ethylene Glycol in Ullmann's Encyclopedia of Industrial Chemistry Electronic Release Wiley\u2010VCH Weinheim2000.","DOI":"10.1002\/14356007.a10_101"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40296-9"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC01848A"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201712732"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201711060"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/celc.201901799"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/c0gc00382d"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00619E"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coelec.2022.101111"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00397"},{"key":"e_1_2_9_12_1","first-page":"2792","volume":"43","author":"Tomilov A. 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