{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T10:08:17Z","timestamp":1784887697496,"version":"3.55.0"},"reference-count":72,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["860762"],"award-info":[{"award-number":["860762"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemSusChem"],"published-print":{"date-parts":[[2026,5,14]]},"abstract":"<jats:p>\n                    The direct arylation of fluoroarenes is a powerful but sustainability\u2010limited transformation, as most established protocols rely on organic solvents and stoichiometric silver additives. Here, we report the first silver\u2010free palladium\u2010catalyzed C\u2013H arylation of fluoroarenes in water containing self\u2010assembled surfactant structures (micelles) as reaction medium. Using the designer surfactant PS\u2010750\u2010M, this sustainable method enables the coupling of diverse pyridines and fluoroarenes under mild conditions, displaying broad functional\u2010group tolerance while fully eliminating organic co\u2010solvents. Mechanistic studies, including kinetics, FT\u2010IR spectroscopy, dynamic light scattering (DLS), and freeze\u2010fracture combined transmission electron microscopy (FF\u2010TEM), reveal the nature of interactions between the catalyst, substrates and distinct micellar domains, providing insight into microenvironmental effects on reactivity and selectivity. The robustness of the catalytic system further allows tandem one\u2010pot sequences, such as C\u2013H arylation\/S\n                    <jats:sub>\n                      <jats:italic>N<\/jats:italic>\n                    <\/jats:sub>\n                    Ar reactions, without intermediate workup or adding an additional catalyst. This work demonstrates how merging micellar catalysis with C\u2013H activation unlocks a practical, environmentally responsible platform for cross\u2010coupling chemistry, expanding the utility of aqueous media for sustainable synthesis.\n                  <\/jats:p>","DOI":"10.1002\/cssc.70661","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:48:30Z","timestamp":1777358910000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Merging Micellar Catalysis and C\u2013H Activation: Silver\u2010Free Direct Arylation of Fluoroarenes in Water"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8411-5211","authenticated-orcid":false,"given":"Federico","family":"Belnome","sequence":"first","affiliation":[{"name":"Van\u2019t Hoff Institute for Molecular Sciences (HIMS) University of Amsterdam  Amsterdam The Netherlands"},{"name":"ThalesNano Inc.  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