{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T07:19:41Z","timestamp":1787901581807,"version":"build-2784847793"},"reference-count":74,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemSusChem"],"published-print":{"date-parts":[[2026,8,27]]},"abstract":"<jats:p>\n                    Lanthanides (Ln) are essential for renewable energy technologies, yet their extraction and recycling often cause severe environmental impacts. Bio\u2010inspired ligands based on metal\u2010binding protein motifs offer a promising alternative for selective and sustainable Ln recovery. This study investigates the lanthanide\u2010binding properties of the EF\u2010hand 4\u2009(EF4) motif of calmodulin. The binding of various Ln\n                    <jats:sup>3+<\/jats:sup>\n                    ions to EF4 was characterized using isothermal titration calorimetry, time\u2010resolved laser fluorescence spectroscopy, nuclear magnetic resonance spectroscopy, and molecular dynamics simulations. EF4 exhibits generally high affinity toward Ln, with slightly varying binding constants across the Ln series. Thermodynamic, structural, and coordination effects associated with Ln binding were analyzed in detail. Compared to the EF\u2010hand loop within the native protein, the isolated EF4 peptide shows significantly increased flexibility. Depending on experimental conditions, both 1:1 and 2:1\u2009(Ln\n                    <jats:sup>3+<\/jats:sup>\n                    :peptide) complex stoichiometries were observed. Furthermore, immobilized EF4 was successfully applied for the extraction and recovery of Sm\n                    <jats:sup>3+<\/jats:sup>\n                    from artificial aqueous solutions under laboratory conditions. Overall, the EF4 loop motif of calmodulin represents a promising biological ligand for the selective binding and recovery of Ln from aqueous systems.\n                  <\/jats:p>","DOI":"10.1002\/cssc.70900","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T13:34:48Z","timestamp":1786541688000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Integrative Approach Toward Bio\u2010Inspired Sequestration of Rare Earth Elements"],"prefix":"10.1002","volume":"19","author":[{"given":"Yulia","family":"Perevedentseva","sequence":"first","affiliation":[{"name":"Institute of Chemistry University of Potsdam Potsdam\u2010Golm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Waurick","sequence":"additional","affiliation":[{"name":"Institute of Resource Ecology Helmholtz\u2010Zentrum Dresden\u2010Rossendorf Dresden 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