{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:39:35Z","timestamp":1787503175659,"version":"build-2736575974"},"reference-count":8,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T00:00:00Z","timestamp":1698364800000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp; Translational Med"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Psychological stress can trigger inflammatory bowel disease (IBD) flares, but the molecular mechanisms have remained unclear. We recently discovered an unexpected function of the enteric nervous system as a relay between stress signals from the brain and intestinal inflammation. Our findings highlight targeting stress\u2010induced signaling networks as a possible new pillar in the clinical management of IBD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ctm2.1458","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T03:33:00Z","timestamp":1698377580000},"source":"Crossref","is-referenced-by-count":7,"title":["From mental strain to gut pain: A brain\u2010gut pathway transducing psychological stress to intestinal inflammation"],"prefix":"10.1002","volume":"13","author":[{"given":"Kai Markus","family":"Schneider","sequence":"first","affiliation":[{"name":"Microbiology Department, Institute for Immunology, and Institute for Diabetes Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"},{"name":"Department of Medicine III University Hospital RWTH Aachen  Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Blank","sequence":"additional","affiliation":[{"name":"Microbiology Department, Institute for Immunology, and Institute for Diabetes Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph A.","family":"Thaiss","sequence":"additional","affiliation":[{"name":"Microbiology Department, Institute for Immunology, and Institute for Diabetes Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2015.186"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2016.06.001"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.529"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2007.11.003"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.05.001"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2022.09.005"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(17)31327\u20102"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco\u2010jcc\/jjy177"}],"container-title":["Clinical and Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ctm2.1458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T08:27:09Z","timestamp":1698395229000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ctm2.1458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/ctm2.1458"],"URL":"https:\/\/doi.org\/10.1002\/ctm2.1458","archive":["Portico"],"relation":{},"ISSN":["2001-1326","2001-1326"],"issn-type":[{"value":"2001-1326","type":"print"},{"value":"2001-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]},"article-number":"e1458"}}