{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:02:48Z","timestamp":1791576168156,"version":"4.3.4"},"reference-count":175,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,16]],"date-time":"2024-06-16T00:00:00Z","timestamp":1718496000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA271497"],"award-info":[{"award-number":["R01 CA271497"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA280389"],"award-info":[{"award-number":["R01 CA280389"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA243386"],"award-info":[{"award-number":["R01 CA243386"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA236399"],"award-info":[{"award-number":["R01 CA236399"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp;amp; Translational Med"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dysregulated RNA modifications, stemming from the aberrant expression and\/or malfunction of RNA modification regulators operating through various pathways, play pivotal roles in driving the progression of haematological malignancies. Among RNA modifications, <jats:italic>N<\/jats:italic><jats:sup>6<\/jats:sup>\u2010methyladenosine (m<jats:sup>6<\/jats:sup>A) RNA modification, the most abundant internal mRNA modification, stands out as the most extensively studied modification. This prominence underscores the crucial role of the layer of epitranscriptomic regulation in controlling haematopoietic cell fate and therefore the development of haematological malignancies. Additionally, other RNA modifications (non\u2010m<jats:sup>6<\/jats:sup>A RNA modifications) have gained increasing attention for their essential roles in haematological malignancies. Although the roles of the m<jats:sup>6<\/jats:sup>A modification machinery in haematopoietic malignancies have been well reviewed thus far, such reviews are lacking for non\u2010m<jats:sup>6<\/jats:sup>A RNA modifications. In this review, we mainly focus on the roles and implications of non\u2010m<jats:sup>6<\/jats:sup>A RNA modifications, including <jats:italic>N<\/jats:italic><jats:sup>4<\/jats:sup>\u2010acetylcytidine, pseudouridylation, 5\u2010methylcytosine, adenosine to inosine editing, 2\u2032\u2010O\u2010methylation, <jats:italic>N<\/jats:italic><jats:sup>1<\/jats:sup>\u2010methyladenosine and <jats:italic>N<\/jats:italic><jats:sup>7<\/jats:sup>\u2010methylguanosine in haematopoietic malignancies. We summarise the regulatory enzymes and cellular functions of non\u2010m<jats:sup>6<\/jats:sup>A RNA modifications, followed by the discussions of the recent studies on the biological roles and underlying mechanisms of non\u2010m<jats:sup>6<\/jats:sup>A RNA modifications in haematological malignancies. We also highlight the potential of therapeutically targeting dysregulated non\u2010m<jats:sup>6<\/jats:sup>A modifiers in blood cancer.<\/jats:p>","DOI":"10.1002\/ctm2.1666","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T04:34:19Z","timestamp":1718598859000},"source":"Crossref","is-referenced-by-count":10,"title":["Non\u2010m<sup>6<\/sup>A RNA modifications in haematological malignancies"],"prefix":"10.1002","volume":"14","author":[{"given":"Meiling","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Hematology Fujian Institute of Hematology Fujian Provincial Key Laboratory on Hematology Fujian Medical University Union Hospital  Fuzhou China"},{"name":"Department of Systems Biology Beckman Research Institute of City of Hope  Monrovia California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanzhong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hematology Fujian Institute of Hematology Fujian Provincial Key Laboratory on Hematology Fujian Medical University Union Hospital  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kitty","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Systems Biology Beckman Research Institute of City of Hope  Monrovia California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolan","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Systems Biology Beckman Research Institute of City of Hope  Monrovia California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3749-2902","authenticated-orcid":false,"given":"Jianjun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Systems Biology Beckman Research Institute of City of Hope  Monrovia California USA"},{"name":"Gehr Family Center for Leukemia Research City of Hope Medical Center and Comprehensive Cancer Center  Duarte California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2020.02.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201802117"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-023-00774-x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cancerbio-030419-033357"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1702"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/BS9.0000000000000124"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.23942"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2020.07.013"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2020.01.021"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1063636"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2016.11.017"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.11.031"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.11.016"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4416"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2020.04.009"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2019.03.021"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2019.03.006"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature24678"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2020.04.001"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2020.04.017"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2020.12.026"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2021.04.017"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2021011707"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2022.10.004"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2023.01.016"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2023.07.001"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2022.12.006"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-13-7342-8_4"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-018-0034-6"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019004263"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-023-00622-x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2020.01.037"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1515\/bchm2.1966.347.1.212"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.7.1.8422966"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.10.030"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad628"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2022.05.016"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2418-2"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2008.154"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv075"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-023-00793-4"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2022.03.008"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-022-01505-w"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-023-01304-7"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3898"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.05.045"},{"key":"e_1_2_11_48_1","doi-asserted-by":"crossref","unstructured":"StockertJA WeilR YadavKK KyprianouN TewariAK.Pseudouridine as a novel biomarker in prostate cancer.Paper presented at: Urologic Oncology: Seminars and Original Investigations.2021;39(1):63\u201071.","DOI":"10.1016\/j.urolonc.2020.06.026"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.77"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0701534104"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.enz.2017.02.001"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2011.427"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genet-112618-043830"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.08.028"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1261\/rna.039610.113"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1330"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq347"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1261\/rna.1007408"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10165"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12302"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1510"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.71.10.3971"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1080\/15476286.2021.1950993"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201500013"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-022-03427-2"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac817"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.18644"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.61439"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1639"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2019.06.033"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201591382"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1186\/gm508"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2017.09.036"},{"key":"e_1_2_11_74_1","doi-asserted-by":"crossref","unstructured":"FritzellK XuL\u2010D LagergrenJ \u00d6hmanM.ADARs and editing: the role of A\u2010to\u2010I RNA modification in cancer progression.Paper presented at: Seminars in Cell & Developmental Biology.2018;79:123\u2010130.","DOI":"10.1016\/j.semcdb.2017.11.018"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37105-8"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/19992"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2015.4"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-018-0006-1"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.12.019"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4172"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-304037"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3110"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2017.07.003"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201694813"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M117.775684"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-021-02287-1"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes10020117"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa002"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac722"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4294"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagrm.2018.11.009"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019004121"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202050095"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0841-4"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-2525-x"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2021108544"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1450"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA117.000837"},{"issue":"13","key":"e_1_2_11_99_1","first-page":"7027","article-title":"3\u02b9\u2010Terminal 2\u02b9\u2010O\u2010methylation of lung cancer miR\u201021\u20105p enhances its stability and association with Argonaute 2","volume":"48","author":"Liang H","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1005620"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11375-7"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-018-0030-z"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.746647"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpb.2018.03.003"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature16998"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.2040"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2022.10.015"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature24456"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1002557"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.09.038"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2018.08.011"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b01703"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.9b00655"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagrm.2018.10.008"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2119038119"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2017.10.019"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20091352"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2838"},{"key":"e_1_2_11_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2019.03.036"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.2c00792"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.7b00906"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2019.03.036"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-019-0230-z"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.05.047"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03973-5"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-022-02551-7"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3570-4"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S197733"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18091924"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112810"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.currproblcancer.2019.06.006"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.598107"},{"key":"e_1_2_11_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.01.015"},{"key":"e_1_2_11_134_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.967811"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20212300"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-09-111245"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101971"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.2777"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06523-4"},{"key":"e_1_2_11_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.008"},{"key":"e_1_2_11_141_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-022-00852-9"},{"key":"e_1_2_11_142_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-021-02342-y"},{"key":"e_1_2_11_143_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-020-01263-w"},{"key":"e_1_2_11_144_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9081758"},{"key":"e_1_2_11_145_1","article-title":"NSUN6, a gene related with m5c methylation, may serve as a biomarker for pan\u2010cancer","author":"Ma B","year":"2022","journal-title":"Research Square"},{"key":"e_1_2_11_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03513-4"},{"key":"e_1_2_11_147_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-0458"},{"key":"e_1_2_11_148_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2015.469"},{"key":"e_1_2_11_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2017.556"},{"key":"e_1_2_11_150_1","doi-asserted-by":"publisher","DOI":"10.1586\/14737140.2014.928595"},{"key":"e_1_2_11_151_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1213021110"},{"key":"e_1_2_11_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.05.004"},{"key":"e_1_2_11_153_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0575-z"},{"issue":"25","key":"e_1_2_11_154_1","first-page":"3078","article-title":"Core\u2010binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis","volume":"141","author":"Guo M","year":"2023","journal-title":"Blood"},{"key":"e_1_2_11_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2022.01.074"},{"key":"e_1_2_11_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01890-w"},{"key":"e_1_2_11_157_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13020256"},{"key":"e_1_2_11_158_1","first-page":"1204","article-title":"ADAR1\u2010mediated GLI1 editing promotes malignant self\u2010renewal in multiple myeloma","volume":"130","author":"Crews L","year":"2017","journal-title":"Blood"},{"key":"e_1_2_11_159_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.778715"},{"key":"e_1_2_11_160_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-022-02445-8"},{"key":"e_1_2_11_161_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.17639"},{"key":"e_1_2_11_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.106864"},{"key":"e_1_2_11_163_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2014-1912"},{"key":"e_1_2_11_164_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41421-022-00460-9"},{"key":"e_1_2_11_165_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-020-0995-6"},{"key":"e_1_2_11_166_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-22-0210"},{"key":"e_1_2_11_167_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-021-08015-z"},{"key":"e_1_2_11_168_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-020-02009-z"},{"key":"e_1_2_11_169_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3563"},{"key":"e_1_2_11_170_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020005823"},{"key":"e_1_2_11_171_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-02-205153"},{"key":"e_1_2_11_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2021.06.031"},{"key":"e_1_2_11_173_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2023.01.008"},{"key":"e_1_2_11_174_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-84908-0"},{"key":"e_1_2_11_175_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.0c00193"},{"issue":"10","key":"e_1_2_11_176_1","first-page":"1569","article-title":"Phase I study of pyrazofurin in refractory acute myelogenous leukemia","volume":"62","author":"Vogler W","year":"1978","journal-title":"Cancer Treat Rep"}],"container-title":["Clinical and Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ctm2.1666","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T03:11:26Z","timestamp":1719285086000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ctm2.1666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":175,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/ctm2.1666"],"URL":"https:\/\/doi.org\/10.1002\/ctm2.1666","archive":["Portico"],"relation":{},"ISSN":["2001-1326","2001-1326"],"issn-type":[{"value":"2001-1326","type":"print"},{"value":"2001-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6]]},"article-number":"e1666"}}