{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T18:17:53Z","timestamp":1765995473678,"version":"3.41.2"},"reference-count":8,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32260896","32188101","82422049","82102389"],"award-info":[{"award-number":["32260896","32188101","82422049","82102389"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp;amp; Translational Med"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p><jats:italic>Dengue virus<\/jats:italic> (DENV) and <jats:italic>Zika virus<\/jats:italic> (ZIKV) have emerged as major global public health challenges, causing numerous infections and fatalities each year. However, current measures, including vaccines and treatments, are often limited or ineffective. This highlights the urgent need for novel preventive strategies to control the spread of key mosquito\u2010borne viruses like DENV and ZIKV. In a recent study published in Science, Zhang et al. isolated a bacterium named <jats:italic>Rosenbergiella<\/jats:italic>_YN46 from the gut of field\u2010caught Aedes albopictus mosquitoes in Yunnan Province, China. This commentary reviews their findings, published on April\u00a019,\u00a02024, which describe the symbiotic bacterium Rosenbergiella_YN46 and its ability to block flavivirus transmission, including both DENV and ZIKV. The bacterium shows promising potential for future dengue fever prevention and provides valuable insights into a novel biological approach for controlling mosquito\u2010borne viral diseases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ctm2.70087","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T12:00:27Z","timestamp":1732881627000},"source":"Crossref","is-referenced-by-count":2,"title":["A symbiotic mosquito\u2010gut bacterium for flavivirus control"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4903-7168","authenticated-orcid":false,"given":"Jinglin","family":"Wang","sequence":"first","affiliation":[{"name":"Yunnan Key Laboratory of Cross\u2010Border Infectious Disease Controlling and Novel Drug Development (Under construction) &amp; Yunnan Provincial Key Laboratory of Public Health and Biosafety School of Public Health, Kunming Medical University  Kunming China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8088-3960","authenticated-orcid":false,"given":"Yibin","family":"Zhu","sequence":"additional","affiliation":[{"name":"New Cornerstone Science Laboratory, Tsinghua University\u2010Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University  Beijing China"},{"name":"Shenzhen Bay Laboratory Institute of Infectious Diseases  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Leng","sequence":"additional","affiliation":[{"name":"Yunnan Key Laboratory of Cross\u2010Border Infectious Disease Controlling and Novel Drug Development (Under construction) &amp; Yunnan Provincial Key Laboratory of Public Health and Biosafety School of Public Health, Kunming Medical University  Kunming China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulin","family":"Yuan","sequence":"additional","affiliation":[{"name":"New Cornerstone Science Laboratory, Tsinghua University\u2010Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingyi","family":"Cao","sequence":"additional","affiliation":[{"name":"New Cornerstone Science Laboratory, Tsinghua University\u2010Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gong","family":"Cheng","sequence":"additional","affiliation":[{"name":"New Cornerstone Science Laboratory, Tsinghua University\u2010Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University  Beijing China"},{"name":"Shenzhen Bay Laboratory Institute of Infectious Diseases  Shenzhen China"},{"name":"Southwest United Graduate School  Kunming China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueshan","family":"Xia","sequence":"additional","affiliation":[{"name":"Yunnan Key Laboratory of Cross\u2010Border Infectious Disease Controlling and Novel Drug Development (Under construction) &amp; Yunnan Provincial Key Laboratory of Public Health and Biosafety School of Public Health, Kunming Medical University  Kunming China"},{"name":"Southwest United Graduate School  Kunming China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2023.10.040"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adn9524"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-021-11323-5"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.1168"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/procel\/pwad021"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.624170"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.08347"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.17202"}],"container-title":["Clinical and Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ctm2.70087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T05:01:04Z","timestamp":1739854864000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ctm2.70087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,29]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/ctm2.70087"],"URL":"https:\/\/doi.org\/10.1002\/ctm2.70087","archive":["Portico"],"relation":{},"ISSN":["2001-1326","2001-1326"],"issn-type":[{"type":"print","value":"2001-1326"},{"type":"electronic","value":"2001-1326"}],"subject":[],"published":{"date-parts":[[2024,11,29]]},"article-number":"e70087"}}