{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T14:39:56Z","timestamp":1776091196586,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,2,20]],"date-time":"2022-02-20T00:00:00Z","timestamp":1645315200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81922006"],"award-info":[{"award-number":["81922006"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870175"],"award-info":[{"award-number":["81870175"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31571528"],"award-info":[{"award-number":["31571528"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LD21H020001"],"award-info":[{"award-number":["LD21H020001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LR15H020001"],"award-info":[{"award-number":["LR15H020001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical & Translational Med"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1002\/ctm2.715","type":"journal-article","created":{"date-parts":[[2022,2,20]],"date-time":"2022-02-20T19:26:33Z","timestamp":1645385193000},"source":"Crossref","is-referenced-by-count":4,"title":["Hyperactivation of platelet\u2010derived growth factor signalling contributes to arrhythmogenesis in Brugada syndrome"],"prefix":"10.1002","volume":"12","author":[{"given":"Hongkun","family":"Wang","sequence":"first","affiliation":[{"name":"Key Laboratory of combined Multi\u2010organ Transplantation, Ministry of Public Health, the First Affiliated Hospital Zhejiang University  Hangzhou China"},{"name":"Institute of Translational Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lizhen","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Biophysics, and Kidney Disease Center of the First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Zhejiang Provincial People's Hospital People's Hospital of Hangzhou Medical College  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaochen","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of combined Multi\u2010organ Transplantation, Ministry of Public Health, the First Affiliated Hospital Zhejiang University  Hangzhou China"},{"name":"Institute of Translational Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Prenatal Diagnosis (Screening) Center Hangzhou Women's Hospital (Hangzhou Maternity and Child Health Care Hospital)  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjun","family":"Zhou","sequence":"additional","affiliation":[{"name":"Key Laboratory of combined Multi\u2010organ Transplantation, Ministry of Public Health, the First Affiliated Hospital Zhejiang University  Hangzhou China"},{"name":"Institute of Translational Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaxi","family":"Shen","sequence":"additional","affiliation":[{"name":"Key Laboratory of combined Multi\u2010organ Transplantation, Ministry of Public Health, the First Affiliated Hospital Zhejiang University  Hangzhou China"},{"name":"Institute of Translational Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zongkuai","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of combined Multi\u2010organ Transplantation, Ministry of Public Health, the First Affiliated Hospital Zhejiang University  Hangzhou China"},{"name":"Institute of Translational Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luyang","family":"Yu","sequence":"additional","affiliation":[{"name":"College of Life Sciences Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhouqing","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardiology the First Affiliated Hospital of Wenzhou Medical University  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingyu","family":"Gong","sequence":"additional","affiliation":[{"name":"Key Laboratory of combined Multi\u2010organ Transplantation, Ministry of Public Health, the First Affiliated Hospital Zhejiang University  Hangzhou China"},{"name":"Institute of Translational Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Medical Genetics Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Biophysics, and Kidney Disease Center of the First Affiliated Hospital Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6806-3735","authenticated-orcid":false,"given":"Ping","family":"Liang","sequence":"additional","affiliation":[{"name":"Key Laboratory of combined Multi\u2010organ Transplantation, Ministry of Public Health, the First Affiliated Hospital Zhejiang University  Hangzhou China"},{"name":"Institute of Translational Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,20]]},"reference":[{"key":"e_1_2_1_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90253-J"},{"key":"e_1_2_1_4_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054131"},{"key":"e_1_2_1_4_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000471792"},{"key":"e_1_2_1_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2018.08.008"},{"key":"e_1_2_1_4_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells7060062"},{"key":"e_1_2_1_4_7_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.70.113006.100455"},{"key":"e_1_2_1_4_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01088"},{"key":"e_1_2_1_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.06.065"},{"key":"e_1_2_1_4_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000442940"},{"key":"e_1_2_1_4_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1406-x"}],"container-title":["Clinical and Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ctm2.715","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ctm2.715","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ctm2.715","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T05:56:43Z","timestamp":1693115803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ctm2.715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1002\/ctm2.715"],"URL":"https:\/\/doi.org\/10.1002\/ctm2.715","archive":["Portico"],"relation":{},"ISSN":["2001-1326","2001-1326"],"issn-type":[{"value":"2001-1326","type":"print"},{"value":"2001-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]},"article-number":"e715"}}