{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T22:10:26Z","timestamp":1697753426848},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T00:00:00Z","timestamp":1119398400000},"content-version":"vor","delay-in-days":8208,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytometry"],"published-print":{"date-parts":[[1983,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A model is presented to compare the separability of cell populations described by features measured in low resolution slitscanning flow systems with their separability when the features are extracted from high resolution digitized cell images. The results show that although the accuracy of the feature measurements deteriorates for increasing slit width, this is not necessarily true for the discriminatory power of the features. Depending on their original position in the high resolution feature space, the cell populations may be located even farther apart in the space of low resolution slit\u2010scan features for reasonably small widths of the slit. The results presented with high resolution images of cells from gynecological specimens and simulated slit\u2010scan measurements can be explained by the model. For the features nuclear DNA content and diameter the abnormal populations are shifted closer to the normal populations in the slit\u2010scan simulations as compared to the high resolution measurements. The cell classifier errors rates are unacceptably high.<\/jats:p>","DOI":"10.1002\/cyto.990030405","type":"journal-article","created":{"date-parts":[[2005,8,8]],"date-time":"2005-08-08T15:33:15Z","timestamp":1123515195000},"page":"257-261","source":"Crossref","is-referenced-by-count":0,"title":["Slit\u2010scan flow cytometry: Separability properties of cell features"],"prefix":"10.1002","volume":"3","author":[{"given":"R. C.","family":"Mann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,22]]},"reference":[{"key":"e_1_2_1_2_2","unstructured":"AchatzM BeckR SegerG: Laser scanning technology for picture analysis of cells.Acta Histochem in press"},{"key":"e_1_2_1_3_2","first-page":"117","article-title":"Optimizing cervical cell classifiers","volume":"22","author":"Castleman KR","year":"1980","journal-title":"Anal Quant Cytol"},{"key":"e_1_2_1_4_2","volume-title":"Fourier transformations and their physical applications","author":"Champeney D","year":"1973"},{"key":"e_1_2_1_5_2","volume-title":"An introduction to probability theory and its applications","author":"Feller W","year":"1957"},{"key":"e_1_2_1_6_2","volume-title":"Introduction to statistical pattern recognition","author":"Fukunaga K","year":"1972"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/27.1.374593"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/26.11.569164"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/27.1.374598"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/27.1.374597"},{"key":"e_1_2_1_11_2","first-page":"443","volume-title":"Flow cytometric analysis of cervical smears and solid tumors. Proceedings of the 4th International Symposium on Flow Cytometry","author":"Linden WA","year":"1980"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-88304-0"},{"key":"e_1_2_1_13_2","volume-title":"Digital image processing","author":"Rosenfeld A","year":"1976"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/24.1.1254921"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/27.1.374618"},{"key":"e_1_2_1_16_2","first-page":"333","article-title":"Slit\u2010scan cytofluorometry","volume":"17","author":"Wheeless LL","year":"1973","journal-title":"Acta Cytol"}],"container-title":["Cytometry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcyto.990030405","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cyto.990030405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T21:51:02Z","timestamp":1697752262000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cyto.990030405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1983,1]]}},"alternative-id":["10.1002\/cyto.990030405"],"URL":"https:\/\/doi.org\/10.1002\/cyto.990030405","archive":["Portico"],"relation":{},"ISSN":["0196-4763","1097-0320"],"issn-type":[{"value":"0196-4763","type":"print"},{"value":"1097-0320","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,1]]}}}