{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T04:56:59Z","timestamp":1698382619276},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,3,8]],"date-time":"2005-03-08T00:00:00Z","timestamp":1110240000000},"content-version":"vor","delay-in-days":3462,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytometry"],"published-print":{"date-parts":[[1995,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The case of a 73\u2010year\u2010old man with B\u2010cell prolymphocytic leukemia (PLL) and rapid clinical demise is reported. Flow cytometric immunophenotyping results of specimens obtained from the patient demonstrated a monoclonal CD5 positive B\u2010cell population with myeloid\u2010associated marker expression, which was discordant: CD15 and CDllb were expressed in bone marrow leukemic cells, whereas peripheral blood leukemic cells showed virtually no expression of these markers. Discordant immunophenotyping results between bone marrow and peripheral blood cells have been reported recently. Additionally, investigators have associated expression of CD13 and CD11b by chronic B\u2010cell lymphoid leukemias with a more aggressive clinical course and shorter survival. Expression of these myeloid\u2010associated antigens by B\u2010cell prolymphocytes in PLL has not been widely reported. Cytogenetic analysis revealed a karyotype of 46,XY\/?44,XYdel(1q),del (3p), whereas molecular genetic studies demonstrated immunoglobulin gene rearrangements in both heavy and light chain regions. Cytochemical staining for PAS (periodic acid\u2010Schiff), nonspecific esterase and methyl\u2010green\u2010pyronin was positive in leukemic cells. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cyto.990220312","type":"journal-article","created":{"date-parts":[[2005,6,30]],"date-time":"2005-06-30T21:48:18Z","timestamp":1120168098000},"page":"243-249","source":"Crossref","is-referenced-by-count":4,"title":["B\u2010cell prolymphocytic leukemia expressing discordant myeloid\u2010associated antigens in simultaneous specimens from bone marrow and peripheral blood"],"prefix":"10.1002","volume":"22","author":[{"given":"Christopher L.","family":"Emery","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald 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