{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T12:52:25Z","timestamp":1695991945435},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,7,6]],"date-time":"2015-07-06T00:00:00Z","timestamp":1436140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytometry Part B Clinical"],"published-print":{"date-parts":[[2015,9,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Chronic lymphocytic leukemia (CLL) is one of the commonest leukemias that has been reported extensively throughout the literature. The characteristic phenotype includes co\u2010expression of CD5 and CD23, along with dim expression of light chain and CD22\/CD79b, with lack of FMC7. The immunophenotypic scoring system given by Matutes has been used to differentiate CLL from non\u2010CLL chronic lymphoproliferative disorders. Various aberrancies have been described in CLL cases, including abnormal (dim or bright) expression of B cell markers and lineage infidel T cell, myelomonocytic, or rarely Natural killer (NK) cells markers. However, the aberrant co\u2010expression of CD56 and CD57 has not yet been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method and Results<\/jats:title><jats:p>We hereby report a case of 62\u2010year female with a typical CLL phenotype and Matutes score of 5, showing the expression of CD56 and CD57.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This entity may represent a rare subtype of CLL which needs to be studied more extensively for its prognostic implications. This is the first report of CLL with aberrant CD56 and CD57 expression. \u00a9 2015 International Clinical Cytometry Society<\/jats:p><\/jats:sec>","DOI":"10.1002\/cyto.b.21254","type":"journal-article","created":{"date-parts":[[2015,5,27]],"date-time":"2015-05-27T00:09:14Z","timestamp":1432685354000},"page":"348-351","source":"Crossref","is-referenced-by-count":5,"title":["Aberrant <scp>NK<\/scp> cell associated marker (<scp>CD<\/scp>56 and <scp>CD<\/scp>57) expression in chronic lymphocytic leukemia"],"prefix":"10.1002","volume":"88","author":[{"given":"Pranav","family":"Dorwal","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Medanta the Medicity Gurgaon Haryana 122 001 India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simmi","family":"Mehra","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Medanta the Medicity Gurgaon Haryana 122 001 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India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vimarsh","family":"Raina","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Medanta the Medicity Gurgaon Haryana 122 001 India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,6]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810701)48:1<198::AID-CNCR2820480131>3.0.CO;2-V"},{"key":"e_1_2_2_3_1","first-page":"253","volume-title":"Chronic Lymphocytic Leukemia: Recent Progress and Future Directions","author":"Rai K.","year":"1987"},{"key":"e_1_2_2_4_1","first-page":"1640","article-title":"The immunological profile of B\u2010cell disorders and proposal of a scoring system for the diagnosis of CLL","volume":"8","author":"Matutes 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