{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:39:11Z","timestamp":1791549551841,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"vor","delay-in-days":31,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytometry Part B Clinical"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>Over the past several years, a diverse group of physicians and other laboratory scientists have developed various recommendations and guidelines regarding best practices for PNH testing. This manuscript is based on these previous recommendations as well as various other relevant publications of experts in the area of PNH testing. The goal is to provide flow cytometry laboratories with an updated consensus approach to analysis and reporting of PNH results and to address the most common analytical challenges for accurate reporting of this rare disease. A comprehensive case library is included in this section. \u00a9 2017 International Clinical Cytometry Society<\/jats:p>","DOI":"10.1002\/cyto.b.21609","type":"journal-article","created":{"date-parts":[[2017,12,13]],"date-time":"2017-12-13T11:44:58Z","timestamp":1513165498000},"page":"49-66","source":"Crossref","is-referenced-by-count":74,"title":["ICCS\/ESCCA Consensus Guidelines to detect GPI\u2010deficient cells in Paroxysmal Nocturnal Hemoglobinuria (PNH) and related Disorders Part 3 \u2013 Data Analysis, Reporting and Case Studies"],"prefix":"10.1002","volume":"94","author":[{"given":"Andrea","family":"Illingworth","sequence":"first","affiliation":[{"name":"Dahl\u2010Chase Diagnostic Services in Bangor  Maine USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iuri","family":"Marinov","sequence":"additional","affiliation":[{"name":"Institute of Hematology and Blood Transfusion Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Robert","family":"Sutherland","sequence":"additional","affiliation":[{"name":"Laboratory Medicine Program Toronto General Hospital Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orianne","family":"Wagner-Ballon","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'H\u00e9matologie et d'Immunologie Biologiques H\u00f4pital Henri Mondor Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"DelVecchio","sequence":"additional","affiliation":[{"name":"Federico II University and CEINGE Institute in Naples Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V86.9.3277.bloodjournal8693277"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2002.03374.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199511093331904"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V76.9.1853.1853"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V87.12.5332.bloodjournal87125332"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0320(20000815)42:4<223::AID-CYTO2>3.0.CO;2-D"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.04992.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1717"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.20525"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.21139"},{"issue":"2","key":"e_1_2_10_12_1","article-title":"Diagnostic screening of paroxysmal nocturnal hemoglobinuria: prospective multicentric evaluation of the current medical indications","volume":"172","author":"Morado M","year":"2016","journal-title":"Cytometry Part B"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13853"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.21023"},{"key":"e_1_2_10_15_1","volume-title":"CLSI H52\u2010A2 Red Blood Cell Diagnostic Testing Using Flow Cytometry; Approved Guideline","author":"Davis BH","year":"2014"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.21111"},{"key":"e_1_2_10_17_1","article-title":"High\u2010sensitivity detection of PNH red blood cells","author":"Sutherland DR","year":"2015","journal-title":"Red Cell Precursors White Blood Cells"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/9781555818722.ch18"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.21174"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.978"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.0327"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.20087"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01686.x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12271"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12661"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V120.21.1271.1271"}],"container-title":["Cytometry Part B: Clinical Cytometry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcyto.b.21609","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cyto.b.21609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T21:02:57Z","timestamp":1692306177000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cyto.b.21609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/cyto.b.21609"],"URL":"https:\/\/doi.org\/10.1002\/cyto.b.21609","archive":["Portico"],"relation":{},"ISSN":["1552-4949","1552-4957"],"issn-type":[{"value":"1552-4949","type":"print"},{"value":"1552-4957","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}