{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T06:06:51Z","timestamp":1779516411535,"version":"3.53.1"},"reference-count":58,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytometry Part B Clinical"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Circulating monocyte partitioning refers to the relative quantification of the three main monocyte subsets in the peripheral blood, namely classical (cMo), intermediate (iMo), and non\u2010classical (ncMo) monocytes, as assessed by flow cytometry, a new nomenclature described 15\u2009years ago. This distribution is influenced by physiological variation as well as by certain therapeutic interventions. In addition, pathological alterations in monocyte partitioning are now well characterized in chronic hematological neoplasms. Most notably, a relative accumulation of cMo exceeding 94% of total circulating monocytes was identified more than a decade ago as a phenotypic hallmark of chronic myelomonocytic leukemia (CMML) and has since been incorporated into the most recent revision of the WHO classification. Altered monocyte partitioning has also been reported in patients with myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs), highlighting its broader relevance across myeloid disorders.<\/jats:p>","DOI":"10.1002\/cyto.b.70041","type":"journal-article","created":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T05:38:18Z","timestamp":1779514698000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Circulating monocyte partitioning and its alteration in hematological chronic neoplasms"],"prefix":"10.1002","author":[{"given":"Sihem","family":"Tarfi","sequence":"first","affiliation":[{"name":"D\u00e9partement d'H\u00e9matologie et Immunologie Biologiques AP\u2010HP, H\u00f4pital Henri Mondor  Cr\u00e9teil France"},{"name":"Univ Paris Est Cr\u00e9teil, INSERM, IMRB  Cr\u00e9teil France"},{"name":"French Group CytHem\u2010LMMC  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Selimoglu\u2010Buet","sequence":"additional","affiliation":[{"name":"French Group CytHem\u2010LMMC  Paris France"},{"name":"INSERM Unit\u00e9 Mixte de Recherche (UMR) 1287, Facult\u00e9 de M\u00e9decine, Universit\u00e9 Paris\u2010Sud, Gustave Roussy  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Sloma","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'H\u00e9matologie et Immunologie Biologiques AP\u2010HP, H\u00f4pital Henri Mondor  Cr\u00e9teil France"},{"name":"Univ Paris Est Cr\u00e9teil, INSERM, IMRB  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9071-6683","authenticated-orcid":false,"given":"Orianne","family":"Wagner\u2010Ballon","sequence":"additional","affiliation":[{"name":"D\u00e9partement d'H\u00e9matologie et Immunologie Biologiques AP\u2010HP, H\u00f4pital Henri Mondor  Cr\u00e9teil France"},{"name":"Univ Paris Est Cr\u00e9teil, INSERM, IMRB  Cr\u00e9teil France"},{"name":"French Group CytHem\u2010LMMC  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the French group CytHem\u2010LMMC","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1182\/blood.2022015850","article-title":"International consensus classification of myeloid neoplasms and acute leukemias: Integrating morphologic, clinical, and genomic data","volume":"140","author":"Arber D. 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