{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T01:02:11Z","timestamp":1787965331365,"version":"build-2784847793"},"reference-count":57,"publisher":"Hindawi Limited","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":2556,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Depress. Anxiety"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1002\/da.20333","type":"journal-article","created":{"date-parts":[[2007,4,10]],"date-time":"2007-04-10T17:50:28Z","timestamp":1176227428000},"page":"E72-E79","source":"Crossref","is-referenced-by-count":15,"title":["Caffeine challenge in patients with panic disorder: baseline differences between those who panic and those who do not"],"prefix":"10.1155","volume":"25","author":[{"given":"Vasilios G.","family":"Masdrakis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiannis G.","family":"Papakostas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikos","family":"Vaidakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charalambos","family":"Papageorgiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artemios","family":"Pehlivanidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"10.1002\/da.20333-BIB1","unstructured":"Depression 10626417 15227162 1996 4 2"},{"key":"crKey-10.1002\/da.20333-BIB1","unstructured":"Anxiety 10709797 15227154 1996 2 5"},{"key":"crKey-10.1002\/da.20333-BIB2","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0006-3223(00)01078-7","article-title":"Persistent respiratory irregularity in patients with panic disorder","volume":"49","author":"Abelson","year":"2001","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20333-BIB2","doi-asserted-by":"crossref","DOI":"10.1002\/da.20179","volume-title":"Evidence for respiratory and nonrespiratory subtypes in panic disorder","author":"Abrams","year":"2006"},{"key":"10.1002\/da.20333-BIB3","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994"},{"key":"10.1002\/da.20333-BIB4","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2000"},{"key":"10.1002\/da.20333-BIB5","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1176\/ajp.151.2.264","article-title":"Triggering the false suffocation alarm in panic disorder patients by using a voluntary breath-holding procedure","volume":"151","author":"Asmundson","year":"1994","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20333-BIB6","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1037\/0021-843X.103.3.553","article-title":"Definitions of panic attacks and panic disorder in the DSM-IV: implications for research","volume":"103","author":"Barlow","year":"1994","journal-title":"J Abnorm Psychol"},{"key":"10.1002\/da.20333-BIB7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF01061844","article-title":"Chronic comparative pharmacokinetics of caffeine in young and elderly men","volume":"11","author":"Blanchard","year":"1983","journal-title":"J Pharmacokinet Biopharm"},{"key":"10.1002\/da.20333-BIB8","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1001\/archpsyc.1983.01790220057009","article-title":"Increased sensitivity to caffeine in patients with panic disorder. Preliminary evidence","volume":"41","author":"Boulenger","year":"1984","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20333-BIB9","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0022-3999(97)00203-1","article-title":"Neurobiology of panic disorder","volume":"44","author":"Bourin","year":"1998","journal-title":"J Psychosom Res"},{"key":"10.1002\/da.20333-BIB10","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1192\/bjp.163.2.201","article-title":"Subtyping of panic disorder by symptom profile","volume":"163","author":"Briggs","year":"1993","journal-title":"Brit J Psychiatry"},{"key":"10.1002\/da.20333-BIB11","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1001\/archpsyc.1992.01820110031004","article-title":"Anxiogenic effects of caffeine in patients with anxiety disorders","volume":"49","author":"Bruce","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20333-BIB12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/(SICI)1520-6394(2000)11:1<15::AID-DA3>3.0.CO;2-W","article-title":"Autonomic reactivity of panic patients during a CO2 inhalation procedure","volume":"11","author":"Bystritsky","year":"2000","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1520-6394(2000)11:1<1::AID-DA1>3.0.CO;2-X","article-title":"Relationship of cognitions to fear of somatic symptoms: a test of the cognitive theory of panic","volume":"11","author":"Chambless","year":"2000","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB14","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1001\/archpsyc.1985.01790260027003","article-title":"Increased anxiogenic effects of caffeine in panic disorders","volume":"42","author":"Charney","year":"1985","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20333-BIB15","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/0005-7967(86)90011-2","article-title":"A cognitive approach to panic","volume":"24","author":"Clark","year":"1986","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20333-BIB16","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1176\/ajp.156.2.229","article-title":"Human brain metabolic response to caffeine and the effects of tolerance","volume":"156","author":"Dager","year":"1999","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20333-BIB17","volume-title":"The SCL-90 Manual I. Scoring, administration and procedures for the SCL-90","author":"Derogatis","year":"1977"},{"key":"10.1002\/da.20333-BIB18","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1037\/0021-843X.101.3.371","article-title":"Increased cardiac awareness in panic disorder","volume":"101","author":"Ehlers","year":"1992","journal-title":"J Abnorm Psychol"},{"key":"10.1002\/da.20333-BIB19","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0005-7967(96)00044-7","article-title":"Anxiety sensitivity, suffocation fear, trait anxiety, and breath-holding duration as predictors of response to carbon dioxide challenge","volume":"34","author":"Eke","year":"1996","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20333-BIB20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/da.1054","article-title":"Acute panic inventory symptoms during CO2 inhalation and room-air hyperventilation among panic disorder patients and normal controls","volume":"14","author":"Goetz","year":"2001","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB21","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1176\/ajp.141.7.857","article-title":"Response to hyperventilation in a group of patients with panic disorder","volume":"141","author":"Gorman","year":"1984","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20333-BIB22","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1176\/appi.ajp.157.4.493","article-title":"Neuroanatomical hypothesis of panic disorder, revised","volume":"157","author":"Gorman","year":"2000","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20333-BIB23","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1002\/da.20333-BIB24","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1176\/appi.ajp.158.1.58","article-title":"Specificity of panic response to CO2 inhalation in panic disorder: a comparison with major depression and premenstrual dysphoric disorder","volume":"158","author":"Kent","year":"2001","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20333-BIB25","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1001\/archpsyc.1993.01820160076009","article-title":"False suffocation alarms, spontaneous panics, and related conditions. An integrative hypothesis","volume":"50","author":"Klein","year":"1993","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20333-BIB26","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0006-3223(91)90119-7","article-title":"Anxiogenic effects of m-CPP in patients with panic disorder: comparison to caffeine's anxiogenic effects","volume":"30","author":"Klein","year":"1991","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20333-BIB27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/(SICI)1520-6394(1998)7:3<130::AID-DA6>3.0.CO;2-F","article-title":"Caffeine use and plasma concentrations in psychiatric outpatients","volume":"7","author":"Lande","year":"1998","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB28","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1176\/ajp.145.5.632","article-title":"Anxiogenic effects of caffeine on panic and depressed patients","volume":"145","author":"Lee","year":"1988","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20333-BIB29","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/da.1072","article-title":"Respiratory variability in panic disorder","volume":"14","author":"Martinez","year":"2001","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB30","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1600-0447.1990.tb01348.x","article-title":"Behavioral and cerebrovascular effects of caffeine in patients with anxiety disorders","volume":"82","author":"Mathew","year":"1990","journal-title":"Acta Psychiatr Scand"},{"key":"10.1002\/da.20333-BIB31","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.jpsychires.2005.09.006","article-title":"Panic attack symptom dimensions and their relationship to illness characteristics in panic disorder","volume":"40","author":"Meuret","year":"2006","journal-title":"J Psychiatr Res"},{"key":"10.1002\/da.20333-BIB32","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S1569-9048(02)00149-0","article-title":"A breath-holding challenge in panic disorder patients, their healthy first-degree relatives, and normal controls","volume":"133","author":"Nardi","year":"2002","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1002\/da.20333-BIB33","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1590\/S0004-282X2003000500003","article-title":"Panic disorder in a breath-holding challenge test: a simple tool for a better diagnosis","volume":"61","author":"Nardi","year":"2003","journal-title":"Arq Neuro-Psiquiatr"},{"key":"10.1002\/da.20333-BIB34","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/da.20165","article-title":"35% carbon dioxide and breath-holding challenge tests in panic disorder: a comparison with spontaneous panic attacks","volume":"23","author":"Nardi","year":"2006","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB35","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1192\/bjp.160.2.165","article-title":"Panic attacks. A neurochemical overview of models and mechanisms","volume":"160","author":"Nutt","year":"1992","journal-title":"Br J Psychiatry"},{"key":"10.1002\/da.20333-BIB36","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/da.20016","article-title":"Language of dyspnea in panic disorder","volume":"20","author":"Perna","year":"2004","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB37","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0005-7916(86)90059-5","article-title":"Cognitive mediation in the affective component of spontaneous panic attacks","volume":"17","author":"Rapee","year":"1986","journal-title":"J Behav Ther Exp Psychiatry"},{"key":"10.1002\/da.20333-BIB38","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1037\/0021-843X.109.4.616","article-title":"Psychological and physiological predictors of response to carbon dioxide challenge in individuals with panic disorder","volume":"109","author":"Rassovsky","year":"2000","journal-title":"J Abnorm Psychol"},{"key":"10.1002\/da.20333-BIB39","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ijpsycho.2005.01.015","article-title":"Physiological markers for anxiety: panic disorder and phobias","volume":"58","author":"Roth","year":"2005","journal-title":"Int J Psychophysiol"},{"key":"10.1002\/da.20333-BIB40","first-page":"419","volume-title":"Kaplan and Sadock's: synopsis of psychiatry-behavioral sciences\/clinical psychiatry","author":"Sadock","year":"2003"},{"key":"10.1002\/da.20333-BIB41","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1001\/archpsyc.1989.01810020059010","article-title":"The influence of an illusion of control on panic attacks induced via inhalation of 5.5% carbon dioxide enriched-air","volume":"46","author":"Sanderson","year":"1989","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20333-BIB42","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1469-8986.1981.tb02486.x","article-title":"Heart beat perception and emotional experience","volume":"18","author":"Schandry","year":"1981","journal-title":"Psychophysiology"},{"key":"10.1002\/da.20333-BIB43","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0165-1781(99)00029-3","article-title":"Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary adrenal axis activation","volume":"86","author":"Sinha","year":"1999","journal-title":"Psychiatry Res"},{"key":"10.1002\/da.20333-BIB44","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0165-0327(00)00337-2","article-title":"How study of respiratory physiology aided our understanding of abnormal brain function in panic disorder","volume":"61","author":"Sinha","year":"2000","journal-title":"J Affect Disord"},{"key":"10.1002\/da.20333-BIB45","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/da.1053","article-title":"The prediction of nonresponse to pharmacotherapy in panic disorder: a review","volume":"14","author":"Slaap","year":"2001","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20333-BIB46","volume-title":"Manual for the state-trait anxiety inventory","author":"Spielberger","year":"1970"},{"key":"10.1002\/da.20333-BIB47","volume-title":"Structured clinical interview for DSM-III-R","author":"Spitzer","year":"1990"},{"key":"10.1002\/da.20333-BIB48","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0887-6185(95)00032-1","article-title":"Effects of anxiety sensitivity and perceived control on emotional responding to caffeine challenge","volume":"10","author":"Telch","year":"1996","journal-title":"J Anxiety Disord"},{"key":"10.1002\/da.20333-BIB49","first-page":"365","volume-title":"Neurobiology of panic disorder (frontiers of clinical neuroscience, vol. 8)","author":"Uhde","year":"1990"},{"key":"10.1002\/da.20333-BIB50","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S0005-7967(97)00031-4","article-title":"Voluntary breath holding: not a suitable probe of the suffocation alarm in panic disorder","volume":"35","author":"Van der Does","year":"1997","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20333-BIB51","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0005-7967(98)00184-3","article-title":"Heartbeat perception in panic disorder: a reanalysis","volume":"38","author":"Van der Does","year":"2000","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20333-BIB52","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/0005-7967(88)90138-6","article-title":"Panic disorder: a product of classical conditioning","volume":"26","author":"Wolpe","year":"1988","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20333-BIB53","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1001\/archpsyc.1988.01800250051007","article-title":"Carbon dioxide-induced anxiety","volume":"45","author":"Woods","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20333-BIB54","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0010-440X(92)90079-6","article-title":"Breath-holding in panic disorder","volume":"33","author":"Zandbergen","year":"1992","journal-title":"Compr Psychiatry"},{"key":"10.1002\/da.20333-BIB55","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0005-7967(98)00202-2","article-title":"Interoceptive accuracy and panic","volume":"37","author":"Zoellner","year":"1999","journal-title":"Behav Res Ther"}],"container-title":["Depression and Anxiety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fda.20333","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/da.20333","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T11:49:28Z","timestamp":1683805768000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/da.20333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":57,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2008,9]]}},"URL":"https:\/\/doi.org\/10.1002\/da.20333","relation":{},"ISSN":["1091-4269","1520-6394"],"issn-type":[{"value":"1091-4269","type":"print"},{"value":"1520-6394","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}