{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:05:53Z","timestamp":1791558353656,"version":"4.3.4"},"reference-count":75,"publisher":"Hindawi Limited","issue":"7","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":2253,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Depress. Anxiety"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1002\/da.20546","type":"journal-article","created":{"date-parts":[[2009,1,11]],"date-time":"2009-01-11T19:53:08Z","timestamp":1231703588000},"page":"641-649","source":"Crossref","is-referenced-by-count":46,"title":["Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?"],"prefix":"10.1155","volume":"26","author":[{"given":"Mitchel A.","family":"Kling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria H.","family":"Coleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Schulkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"10.1002\/da.20546-BIB1","unstructured":"World Health Organization. Depression. http:\/\/www.who.int\/mental_health\/management\/depression\/definition\/en\/, accessed on April 23, 2007."},{"key":"10.1002\/da.20546-BIB2","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR","author":"American Psychiatric Association","year":"2000"},{"key":"10.1002\/da.20546-BIB3","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1038\/sj.npp.1300884","article-title":"Clinical and biological effects of mifepristone treatment for psychotic depression","volume":"31","author":"Flores","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1002\/da.20546-BIB4","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/01.nmd.0000177791.33649.69","article-title":"Differential response to combined treatment in patients with psychotic versus non-psychotic major depression","volume":"193","author":"Gaudiano","year":"2005","journal-title":"J Nerv Ment Dis"},{"key":"10.1002\/da.20546-BIB5","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0006-3223(02)01432-4","article-title":"An open label trial of C-1073 (mifepristone) for psychotic major depression","volume":"52","author":"Belanoff","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB6","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1600-0447.2007.00967.x","article-title":"Pathophysiology of hypercortisolism in depression","volume":"433","author":"Carroll","year":"2007","journal-title":"Acta Psychiatr Scand Suppl"},{"key":"10.1002\/da.20546-BIB7","first-page":"1839","volume-title":"Principles and Practice of Endocrinology and Metabolism","author":"Kling","year":"2001"},{"key":"10.1002\/da.20546-BIB8","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1017\/S0033291700007480","article-title":"Urinal free cortisol excretion in depression","volume":"6","author":"Carroll","year":"1976","journal-title":"Psychol Med"},{"key":"10.1002\/da.20546-BIB9","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/sj.mp.4001032","article-title":"Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs. low CRH\/NE states","volume":"7","author":"Gold","year":"2002","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20546-BIB10","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1002\/hup.396","article-title":"New directions in the development of antidepressants: the interface of neurobiology and psychiatry","volume":"17","author":"Nemeroff","year":"2002","journal-title":"Hum Psychopharmacol"},{"key":"10.1002\/da.20546-BIB11","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1001\/archpsyc.1992.01820050048008","article-title":"Adrenal gland enlargement in major depression: a computed tomographic study","volume":"49","author":"Nemeroff","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20546-BIB12","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0018-506X(02)00016-8","article-title":"Neuroendocrine aspects of hypercortisolism in major depression","volume":"43","author":"Parker","year":"2003","journal-title":"Horm Behav"},{"key":"10.1002\/da.20546-BIB13","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/00004714-200110000-00009","article-title":"Rapid reversal of psychotic depression using mifepristone","volume":"21","author":"Belanoff","year":"2001","journal-title":"J Clin Psychopharmacol"},{"key":"10.1002\/da.20546-BIB14","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1176\/ajp.154.11.1497","article-title":"DST studies in psychotic depression: a meta-analysis","volume":"154","author":"Nelson","year":"1997","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20546-BIB15","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1365-2265.1995.tb02614.x","article-title":"Psychopathology in patients with endogenous Cushing's syndrome: \u2018atypical\u2019 or melancholic features","volume":"43","author":"Dorn","year":"1995","journal-title":"Clin Endocrinol"},{"key":"10.1002\/da.20546-BIB16","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1176\/ajp.142.8.911","article-title":"Diagnostic categorization of psychiatric disturbance in Cushing's syndrome","volume":"142","author":"Haskett","year":"1985","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20546-BIB17","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00006842-198102000-00002","article-title":"Depressed mood and other psychiatric manifestations of Cushing's syndrome: relationship to hormone levels","volume":"43","author":"Starkman","year":"1981","journal-title":"Psychosom Med"},{"key":"10.1002\/da.20546-BIB18","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1001\/archpsyc.1981.01780290105011","article-title":"Side effects of corticosteroid therapy: psychiatric aspects","volume":"38","author":"Ling","year":"1981","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20546-BIB19","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0960-0760(91)90069-H","article-title":"Treatment of major depression with steroid suppressive drugs","volume":"39","author":"Murphy","year":"1991","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1002\/da.20546-BIB20","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1176\/ajp.150.5.810","article-title":"Ketoconazole treatment of hypercortisolemic depression","volume":"150","author":"Wolkowitz","year":"1993","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20546-BIB21","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jad.2005.04.001","article-title":"Cognitive, physiological, and personality correlates of recurrence of depression","volume":"87","author":"Bos","year":"2005","journal-title":"J Affect Disord"},{"key":"10.1002\/da.20546-BIB22","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3758\/CABN.1.1.96","article-title":"Enhancement of serotonin uptake by cortisol: a possible link between stress and depression","volume":"1","author":"Tafet","year":"2001","journal-title":"Cogn Affect Behav Neurosci"},{"key":"10.1002\/da.20546-BIB23","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0006-3223(96)00312-5","article-title":"Low cerebrospinal fluid corticotropin-releasing hormone concentrations in eucortisolemic depression","volume":"42","author":"Geracioti","year":"1997","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB24","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJM198605223142101","article-title":"Response to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease","volume":"314","author":"Gold","year":"1986","journal-title":"N Engl J Med"},{"key":"10.1002\/da.20546-BIB25","first-page":"135","article-title":"Etiologic implications of corticosteroid changes in affective disorder","volume":"3","author":"Kathol","year":"1985","journal-title":"Psychiatr Med"},{"key":"10.1002\/da.20546-BIB26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s002130100737","article-title":"Reduction in basal afternoon plasma ACTH during early treatment of depression with fluoxetine","volume":"156","author":"Inder","year":"2001","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1002\/da.20546-BIB27","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD005168.pub2","volume-title":"Antiglucocorticoid Treatments for Mood Disorders","author":"Gallagher","year":"2008"},{"key":"10.1002\/da.20546-BIB28","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1038\/sj.npp.1300471","article-title":"Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder","volume":"29","author":"Young","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1002\/da.20546-BIB29","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archpsyc.1994.03950090033005","article-title":"Increased circadian activation of the hypothalamic pituitary adrenal axis in depressed patients in the evening","volume":"51","author":"Young","year":"1994","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20546-BIB30","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/S0006-3223(96)00291-0","article-title":"Normal pituitary response to metyrapone in the morning in depressed patients: implications for circadian regulation of CRH secretion","volume":"41","author":"Young","year":"1997","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB31","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.biopsych.2005.10.014","article-title":"Cortisol circadian rhythm alterations in psychotic major depression","volume":"60","author":"Keller","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB32","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1001\/archpsyc.1988.01800340094019","article-title":"Effect of ketoconazole on a hypophysectomized, hypercortisolemic, psychotically depressed woman (letter)","volume":"45","author":"Ravaris","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20546-BIB33","first-page":"209","article-title":"Possible use of glucocorticoid receptor antagonists in the treatment of major depression: preliminary results using RU 486","volume":"18","author":"Murphy","year":"1993","journal-title":"J Psychiatry Neurosci"},{"key":"10.1002\/da.20546-BIB34","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0006-3223(94)00150-2","article-title":"The psychotropic effects of inhibitors of steroid biosynthesis in depressed patients refractory to treatment","volume":"37","author":"Ghadirian","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB35","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/S0006-3223(98)00267-4","article-title":"Antiglucocorticoid treatment of depression: double-blind ketoconazole","volume":"45","author":"Wolkowitz","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB36","first-page":"199","volume-title":"Refractory Depression","author":"Amsterdam","year":"1994"},{"key":"10.1002\/da.20546-BIB37","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/0006-3223(94)00137-R","article-title":"Cortisol synthesis inhibition: a new treatment strategy for the clinical and endocrine manifestations of depression","volume":"37","author":"Thakore","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB38","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/0006-3223(94)00245-X","article-title":"Antiglucocorticoid treatment of refractory depression with ketoconazole: a case report","volume":"37","author":"Anand","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB39","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0165-0327(94)00082-K","article-title":"Treatment of major depression with metyrapone and hydrocortisone","volume":"33","author":"O'Dwyer","year":"1995","journal-title":"J Affect Disord"},{"key":"10.1002\/da.20546-BIB40","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1097\/00004714-199910000-00011","article-title":"Limited efficacy of ketoconazole in treatment refractory major depression","volume":"19","author":"Malison","year":"1999","journal-title":"J Clin Psychopharmacol"},{"key":"10.1002\/da.20546-BIB41","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1517\/13543784.10.10.1789","article-title":"Antiglucocorticoid drugs in the treatment of depression","volume":"10","author":"Reus","year":"2001","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1002\/da.20546-BIB42","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1001\/archpsyc.61.12.1235","article-title":"Metyrapone as additive treatment in major depression: a double-blind and placebo-controlled trial","volume":"61","author":"Jahn","year":"2004","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20546-BIB43","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/00131746-200307000-00009","article-title":"Effectiveness of antiglucocorticoid therapy in a patient with psychotic depression and ectopic ACTH production","volume":"9","author":"Stowell","year":"2003","journal-title":"J Psychiatr Pract"},{"key":"10.1002\/da.20546-BIB44","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1124\/mol.52.4.571","article-title":"Steroid-independent translocation of the glucocorticoid receptor by the antidepressant desipramine","volume":"52","author":"Pariante","year":"1997","journal-title":"Mol Pharmacol"},{"key":"10.1002\/da.20546-BIB45","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0006-3223(00)01088-X","article-title":"Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment","volume":"49","author":"Pariante","year":"2001","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB46","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0006-3223(02)01480-4","article-title":"New insights into the role of cortisol and the glucocorticoid receptor in severe depression","volume":"52","author":"Gold","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20546-BIB47","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1056\/NEJM198808113190606","article-title":"Clinical and biochemical manifestations of depression: relationship to the neurobiology of stress, part 1","volume":"319","author":"Gold","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1002\/da.20546-BIB48","doi-asserted-by":"crossref","first-page":"R591","DOI":"10.1152\/ajpregu.00233.2002","article-title":"Disinhibition of female sexual behavior by a CRH receptor antagonist in Syrian hamsters","volume":"283","author":"Jones","year":"2002","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1002\/da.20546-BIB49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1210\/edrv-5-1-1","article-title":"Corticosteroid inhibition of ACTH secretion","volume":"5","author":"Keller-Wood","year":"1984","journal-title":"Endocr Rev"},{"key":"10.1002\/da.20546-BIB50","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0091-3057(01)00687-6","article-title":"Glucose metabolism in the amygdala in depression: relationship to diagnostic subtype and plasma cortisol levels","volume":"71","author":"Drevets","year":"2002","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1002\/da.20546-BIB51","doi-asserted-by":"crossref","first-page":"3628","DOI":"10.1523\/JNEUROSCI.12-09-03628.1992","article-title":"A functional anatomical study of unipolar depression","volume":"12","author":"Drevets","year":"1992","journal-title":"J Neurosci"},{"key":"10.1002\/da.20546-BIB52","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/0006-8993(94)91382-X","article-title":"Restraint stress increases corticotrophin releasing hormone mRNA content in the amygdala and the paraventricular nucleus","volume":"656","author":"Kalin","year":"1994","journal-title":"Brain Res"},{"key":"10.1002\/da.20546-BIB53","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1126\/science.6267699","article-title":"Characterization of a 41-residue ovine hypothalamic peptide that stimulates the secretion of corticotrophin releasing hormone and beta-endorphin","volume":"213","author":"Vale","year":"1981","journal-title":"Science"},{"key":"10.1002\/da.20546-BIB54","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0006-8993(00)02905-X","article-title":"Cerebral hemisphere regulation of motivated behavior","volume":"886","author":"Swanson","year":"2000","journal-title":"Brain Res"},{"key":"10.1002\/da.20546-BIB55","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0006-8993(87)90058-8","article-title":"Evidence for local site of action for glucocorticoids in inhibiting CRH and vasopressin expression in the paraventricular nucleus","volume":"17","author":"Sawchenko","year":"1987","journal-title":"Brain Res"},{"key":"10.1002\/da.20546-BIB56","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/cne.902850402","article-title":"Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat","volume":"285","author":"Swanson","year":"1989","journal-title":"J Comp Neurol"},{"key":"10.1002\/da.20546-BIB57","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1523\/JNEUROSCI.10-04-01062.1990","article-title":"The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioning","volume":"10","author":"LeDoux","year":"1990","journal-title":"J Neurosci"},{"key":"10.1002\/da.20546-BIB58","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1037\/0033-295X.105.2.325","article-title":"From normal fear to pathological anxiety","volume":"105","author":"Rosen","year":"1998","journal-title":"Psychol Rev"},{"key":"10.1002\/da.20546-BIB59","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1098\/rstb.1997.0149","article-title":"Amygdala and bed nucleus of the stria terminalis: differential roles in fear and anxiety measured with the acoustic startle reflex","volume":"352","author":"Davis","year":"1997","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1002\/da.20546-BIB60","doi-asserted-by":"crossref","first-page":"407","DOI":"10.31887\/DCNS.2006.8.4\/jschulkin","article-title":"Angst and the amygdala","volume":"8","author":"Schulkin","year":"2006","journal-title":"Dialogues Clin Neurosci"},{"key":"10.1002\/da.20546-BIB61","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.tins.2005.09.009","article-title":"A neuroendocrine mechanism for sustaining fear","volume":"28","author":"Schulkin","year":"2005","journal-title":"Trends Neurosci"},{"key":"10.1002\/da.20546-BIB62","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0006-8993(94)90961-X","article-title":"Effects of corticosterone on CRH mRNA and content in the bed nucleus of the stria terminalis comparison with the effects in the central nucleus of the amygdala and the paraventricular nucleus of the hypothalamus","volume":"657","author":"Makino","year":"1994","journal-title":"Brain Res"},{"key":"10.1002\/da.20546-BIB63","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1113\/jphysiol.1995.sp020698","article-title":"Region-specific regulation of neuropeptide mRNAs in rat limbic forebrain neurons by aldosterone and corticosterone","volume":"484","author":"Watts","year":"1995","journal-title":"J Physiol (London)"},{"key":"10.1002\/da.20546-BIB64","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1749-6632.1994.tb39267.x","article-title":"Glucocorticoid receptor (GR)-mediated effects on cocaine kindling in rats","volume":"746","author":"Kling","year":"1994","journal-title":"Ann N Y Acad Sci"},{"key":"10.1002\/da.20546-BIB65","first-page":"392","volume-title":"Annals of the New York Academy of Sciences","volume":"746","author":"Corodimas","year":"1994"},{"key":"10.1002\/da.20546-BIB66","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0006-8993(94)90286-0","article-title":"Effect of corticosterone on the enhancement of the acoustic startle reflex by corticotrophin releasing hormone","volume":"666","author":"Lee","year":"1994","journal-title":"Brain Res"},{"key":"10.1002\/da.20546-BIB67","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/BF00235319","article-title":"Projections of the bed nucleus of the stria terminalis to the mesencephalon, pons, and medulla oblongata in the cat","volume":"58","author":"Holstege","year":"1985","journal-title":"Exp Brain Res"},{"key":"10.1002\/da.20546-BIB68","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1002\/1096-9861(20000710)422:4<533::AID-CNE5>3.0.CO;2-7","article-title":"Supracapsular bed nucleus of the stria terminalis contains central and medial extended amygdala elements: evidence from anterograde and retrograde tracing experiments in the rat","volume":"422","author":"Shammah-Lagnado","year":"2000","journal-title":"J Comp Neurol"},{"key":"10.1002\/da.20546-BIB69","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0166-4328(03)00216-X","article-title":"Corticosterone facilitates retention of contextually conditioned fear and increases CRH mRNA expression in the amygdala","volume":"149","author":"Thompson","year":"2004","journal-title":"Behav Brain Res"},{"key":"10.1002\/da.20546-BIB70","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1111\/j.1460-9568.2007.05972.x","article-title":"Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress","volume":"26","author":"Oomen","year":"2007","journal-title":"Eur J Neurosci"},{"key":"10.1002\/da.20546-BIB71","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.bbr.2005.06.020","article-title":"Glucocorticoid receptor antagonism in the basolateral amygdala and ventral hippocampus interferes with long-term memory of contextual fear","volume":"164","author":"Donley","year":"2005","journal-title":"Behav Brain Res"},{"key":"10.1002\/da.20546-BIB72","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0006-8993(00)02019-9","article-title":"Corticosterone delivery to the amygdala increases corticotropin-releasing factor mRNA in the central amygdaloid nucleus and anxiety-like behavior","volume":"861","author":"Shepard","year":"2000","journal-title":"Brain Res"},{"key":"10.1002\/da.20546-BIB73","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.bbr.2006.07.019","article-title":"Chronically elevated corticosterone in the amygdala increases corticotropin releasing factor mRNA in the dorsolateral bed nucleus of stria terminalis following duress","volume":"174","author":"Shepard","year":"2006","journal-title":"Behav Brain Res"},{"key":"10.1002\/da.20546-BIB74","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bbr.2005.03.001","article-title":"Corticosterone implants to the amygdala and type 1 CRH receptor regulation: effects on behavior and colonic sensitivity","volume":"161","author":"Myers","year":"2005","journal-title":"Behav Brain Res"},{"key":"10.1002\/da.20546-BIB75","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S0031-9384(02)00650-9","article-title":"Glucocorticoid feedback increases the sensitivity of the limbic system to stress","volume":"75","author":"Cook","year":"2002","journal-title":"Physiol Behav"}],"container-title":["Depression and Anxiety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fda.20546","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/da.20546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:03:47Z","timestamp":1671541427000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/da.20546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":75,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,7]]}},"URL":"https:\/\/doi.org\/10.1002\/da.20546","relation":{},"ISSN":["1091-4269","1520-6394"],"issn-type":[{"value":"1091-4269","type":"print"},{"value":"1520-6394","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}