{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T07:19:47Z","timestamp":1781421587126,"version":"3.54.1"},"reference-count":115,"publisher":"Hindawi Limited","issue":"12","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1538,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Depress. Anxiety"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1002\/da.20840","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T22:52:51Z","timestamp":1308351171000},"page":"1048-1057","source":"Crossref","is-referenced-by-count":64,"title":["Serotonin transporter gene and childhood trauma - a G \u00d7 E effect on anxiety sensitivity"],"prefix":"10.1155","volume":"28","author":[{"given":"Benedikt","family":"Klauke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Deckert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Reif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Pauli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Zwanzger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Baumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Arolt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Gl\u00f6ckner-Rist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Domschke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","published-online":{"date-parts":[[2011,6,16]]},"reference":[{"key":"10.1002\/da.20840-BIB1|cit3","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1176\/appi.ajp.158.10.1568","article-title":"A review and meta-analysis of the genetic epidemiology of anxiety disorders","volume":"158","author":"Hettema","year":"2001","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB2|cit4","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1017\/S0033291799008429","article-title":"Fears and phobias: reliability and heritability","volume":"29","author":"Kendler","year":"1999","journal-title":"Psychol Med"},{"key":"10.1002\/da.20840-BIB3|cit5","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1001\/archpsyc.62.2.182","article-title":"The structure of genetic and environmental risk factors for anxiety disorders in men and women","volume":"62","author":"Hettema","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20840-BIB4|cit6","first-page":"868","article-title":"Study on the current situation and influential factors of anxiety sensitivity among middle school students in Chongqing","volume":"28","author":"Li","year":"2007","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"10.1002\/da.20840-BIB5|cit7","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1176\/ajp.156.2.246","article-title":"Heritability of anxiety sensitivity: a twin study","volume":"156","author":"Stein","year":"1999","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB6|cit8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0005-7967(86)90143-9","article-title":"Anxiety sensitivity, anxiety frequency and the prediction of fearfulness","volume":"24","author":"Reiss","year":"1986","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20840-BIB7|cit9","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1037\/0021-843X.106.3.355","article-title":"The role of anxiety sensitivity in the pathogenesis of panic: prospective evaluation of spontaneous panic attacks during acute stress","volume":"106","author":"Schmidt","year":"1997","journal-title":"J Abnorm Psychol"},{"key":"10.1002\/da.20840-BIB8|cit10","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1037\/0021-843X.108.3.532","article-title":"Prospective evaluation of anxiety sensitivity in the pathogenesis of panic: replication and extension","volume":"108","author":"Schmidt","year":"1999","journal-title":"J Abnorm Psychol"},{"key":"10.1002\/da.20840-BIB9|cit11","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jpsychires.2006.07.009","article-title":"Anxiety sensitivity: prospective prediction of panic attacks and Axis I pathology","volume":"40","author":"Schmidt","year":"2006","journal-title":"J Psychiatr Res"},{"key":"10.1002\/da.20840-BIB10|cit12","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1207\/S15327752JPA7702_10","article-title":"The anxiety sensitivity index: item analysis and suggestions for refinement","volume":"77","author":"Blais","year":"2001","journal-title":"J Pers Assess"},{"key":"10.1002\/da.20840-BIB11|cit13","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/978-90-481-2298-1_8","volume-title":"The Handbook of Neuropsychiatric Biomarkers, Endophenotypes, and Genes","author":"Domschke","year":"2009"},{"key":"10.1002\/da.20840-BIB12|cit14","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1586\/ern.10.76","article-title":"Genetics of panic disorder: focus on association studies and therapeutic perspectives","volume":"10","author":"Jacob","year":"2010","journal-title":"Expert Rev Neurother"},{"key":"10.1002\/da.20840-BIB13|cit15","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/mp.2009.145","article-title":"Advances in molecular genetics of panic disorder","volume":"15","author":"Maron","year":"2010","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB14|cit16","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1038\/nn1964","article-title":"Long story short: the serotonin transporter in emotion regulation and social cognition","volume":"10","author":"Canli","year":"2007","journal-title":"Nat Neurosci"},{"key":"10.1002\/da.20840-BIB15|cit17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF01244919","article-title":"Isolation of a cDNA encoding the human brain serotonin transporter","volume":"91","author":"Lesch","year":"1993","journal-title":"J Neural Transm Gen Sect"},{"key":"10.1002\/da.20840-BIB16|cit18","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1126\/science.274.5292.1527","article-title":"Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region","volume":"274","author":"Lesch","year":"1996","journal-title":"Science"},{"key":"10.1002\/da.20840-BIB17|cit19","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1176\/appi.ajp.161.3.569","article-title":"Association between allelic variation of serotonin transporter function and neuroticism in anxious cluster C personality disorders","volume":"161","author":"Jacob","year":"2004","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB18|cit20","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1001\/archpsyc.55.10.936","article-title":"Role of the serotonin transporter promoter polymorphism in anxiety-related traits","volume":"55","author":"Mazzanti","year":"1998","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20840-BIB19|cit21","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/sj.mp.4001405","article-title":"A meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety","volume":"9","author":"Schinka","year":"2004","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB20|cit22","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/ajmg.b.20158","article-title":"Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits","volume":"127B","author":"Sen","year":"2004","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1002\/da.20840-BIB21|cit23","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1038\/sj.mp.4000782","article-title":"Association of a functional polymorphism of the serotonin transporter gene with anxiety-related temperament and behavior problems in children: a longitudinal study from infancy to the mid-teens","volume":"5","author":"Jorm","year":"2000","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB22|cit24","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1176\/appi.ajp.160.4.671","article-title":"Relation of shyness in grade school children to the genotype for the long form of the serotonin transporter promoter region polymorphism","volume":"160","author":"Arbelle","year":"2003","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB23|cit25","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S0006-3223(98)00090-0","article-title":"Association between serotonin transporter gene polymorphism and anxiety-related traits","volume":"45","author":"Katsuragi","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20840-BIB24|cit26","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1007\/s10519-006-9139-7","article-title":"Family based association analyses between the serotonin transporter gene polymorphism (5-HTTLPR) and neuroticism, anxiety and depression","volume":"37","author":"Middeldorp","year":"2007","journal-title":"Behav Genet"},{"key":"10.1002\/da.20840-BIB25|cit27","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1037\/0021-843X.109.2.308","article-title":"Evaluating gene x psychological risk factor effects in the pathogenesis of anxiety: a new model approach","volume":"109","author":"Schmidt","year":"2000","journal-title":"J Abnorm Psychol"},{"key":"10.1002\/da.20840-BIB26|cit28","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/0269881110372543","article-title":"Genetic moderation of CO2- induced fear by 5-HTTPLPR genotype","volume":"25","author":"Schruers","year":"2011","journal-title":"J Psychopharmacol"},{"key":"10.1002\/da.20840-BIB27|cit29","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1097\/00001756-199703240-00048","article-title":"The serotonin transporter gene and peer-rated neuroticism","volume":"8","author":"Ball","year":"1997","journal-title":"Neuroreport"},{"key":"10.1002\/da.20840-BIB28|cit30","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/sj.mp.4000275","article-title":"No association between the serotonin transporter gene regulatory region polymorphism and the Tridimensional Personality Questionnaire (TPQ) temperament of harm avoidance","volume":"2","author":"Ebstein","year":"1997","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB29|cit31","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/sj.mp.4000466","article-title":"Neuroticism is not associated with the serotonin transporter (5-HTTLPR) polymorphism","volume":"4","author":"Flory","year":"1999","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB30|cit32","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/sj.mp.4000424","article-title":"An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms","volume":"3","author":"Jorm","year":"1998","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB31|cit33","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0304-3940(99)00098-1","article-title":"Study of the association between the serotonin transporter gene regulatory region polymorphism and personality traits in a Japanese population","volume":"263","author":"Kumakiri","year":"1999","journal-title":"Neurosci Lett"},{"key":"10.1002\/da.20840-BIB32|cit34","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1159\/000077363","article-title":"No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits","volume":"49","author":"Lang","year":"2004","journal-title":"Neuropsychobiology"},{"key":"10.1002\/da.20840-BIB33|cit35","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1002\/ajmg.b.30808","article-title":"5-HTTLPR genotype and anxiety-related personality traits: a meta-analysis and new data","volume":"150B","author":"Munafo","year":"2009","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1002\/da.20840-BIB34|cit36","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1002\/(SICI)1096-8628(19970919)74:5<544::AID-AJMG18>3.0.CO;2-C","article-title":"Serotonin transporter gene regulatory region polymorphism and anxiety-related traits in the Japanese","volume":"74","author":"Nakamura","year":"1997","journal-title":"Am J Med Genet"},{"key":"10.1002\/da.20840-BIB35|cit37","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/gm161","article-title":"Serotonin transporter polymorphisms and panic disorder","volume":"2","author":"Schumacher","year":"2010","journal-title":"Genome Med"},{"key":"10.1002\/da.20840-BIB36|cit38","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1744-9081-3-41","article-title":"Lack of association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR) and Panic Disorder: a systematic review and meta-analysis","volume":"3","author":"Blaya","year":"2007","journal-title":"Behav Brain Funct"},{"key":"10.1002\/da.20840-BIB37|cit39","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/00041444-199700710-00008","article-title":"Functional promoter polymorphism of the human serotonin transporter: lack of association with panic disorder","volume":"7","author":"Deckert","year":"1997","journal-title":"Psychiatr Genet"},{"key":"10.1002\/da.20840-BIB38|cit40","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1440-1819.1997.tb03208.x","article-title":"An association study between a transcriptional polymorphism in the serotonin transporter gene and panic disorder in a Japanese population","volume":"51","author":"Ishiguro","year":"1997","journal-title":"Psychiatry Clin Neurosci"},{"key":"10.1002\/da.20840-BIB39|cit41","first-page":"210","article-title":"Serotonin gene polymorphisms in patients with panic disorder","volume":"33","author":"Martinez-Barrondo","year":"2005","journal-title":"Actas Esp Psiquiatr"},{"key":"10.1002\/da.20840-BIB40|cit42","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/sj.mp.4000303","article-title":"Serotonin transporter gene regulatory region polymorphism and panic disorder","volume":"2","author":"Matsushita","year":"1997","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB41|cit43","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.psychres.2004.05.012","article-title":"Association studies of MAO-A, COMT, and 5-HTT genes polymorphisms in patients with anxiety disorders of the phobic spectrum","volume":"128","author":"Samochowiec","year":"2004","journal-title":"Psychiatry Res"},{"key":"10.1002\/da.20840-BIB42|cit44","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0165-1781(98)00117-6","article-title":"Genetic linkage to the serotonin transporter protein and 5HT2A receptor genes excluded in generalized social phobia","volume":"81","author":"Stein","year":"1998","journal-title":"Psychiatry Res"},{"key":"10.1002\/da.20840-BIB43|cit45","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/mp.2008.79","article-title":"Panic disorder is associated with the serotonin transporter gene (SLC6A4) but not the promoter region (5-HTTLPR)","volume":"15","author":"Strug","year":"2010","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB44|cit46","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.pnpbp.2009.08.004","article-title":"The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism","volume":"33","author":"Lonsdorf","year":"2009","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1002\/da.20840-BIB45|cit47","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0165-1781(98)00100-0","article-title":"Association between anxiety disorders and a functional polymorphism in the serotonin transporter gene","volume":"81","author":"Ohara","year":"1998","journal-title":"Psychiatry Res"},{"key":"10.1002\/da.20840-BIB46|cit48","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1017\/S1461145704004985","article-title":"Associations between serotonin-related gene polymorphisms and panic disorder","volume":"8","author":"Maron","year":"2005","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1002\/da.20840-BIB47|cit49","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/sj.mp.4000550","article-title":"Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder","volume":"4","author":"Bengel","year":"1999","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB48|cit50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00041444-199903000-00001","article-title":"Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder","volume":"9","author":"Hamilton","year":"1999","journal-title":"Psychiatr Genet"},{"key":"10.1002\/da.20840-BIB49|cit51","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/sj.mp.4000391","article-title":"Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder","volume":"3","author":"McDougle","year":"1998","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB50|cit52","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1053\/comp.2002.33492","article-title":"Early traumatic life events, parental attitudes, family history, and birth risk factors in patients with panic disorder","volume":"43","author":"Bandelow","year":"2002","journal-title":"Compr Psychiatry"},{"key":"10.1002\/da.20840-BIB51|cit53","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1017\/S0033291700038939","article-title":"Aetiology of anxiety and depressive disorders in an inner-city population. 1. Early adversity","volume":"23","author":"Brown","year":"1993","journal-title":"Psychol Med"},{"key":"10.1002\/da.20840-BIB52|cit54","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1176\/ajp.153.2.275","article-title":"Childhood physical and sexual abuse in patients with anxiety disorders and in a community sample","volume":"153","author":"Stein","year":"1996","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB53|cit55","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1177\/070674370104601007","article-title":"Separation anxiety and actual separation experiences during childhood in patients with panic disorder","volume":"46","author":"Bandelow","year":"2001","journal-title":"Can J Psychiatry"},{"key":"10.1002\/da.20840-BIB54|cit56","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1001\/archpsyc.1992.01820020029004","article-title":"Childhood parental loss and adult psychopathology in women. A twin study perspective","volume":"49","author":"Kendler","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20840-BIB55|cit57","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/da.20667","article-title":"Life events in panic disorder-an update on \u201ccandidate stressors\u201d","volume":"27","author":"Klauke","year":"2010","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20840-BIB56|cit58","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1023\/A:1023572923371","article-title":"The role of anxiety sensitivity components in mediating the relationship between childhood exposure to parental dyscontrol and adult anxiety symptoms","volume":"25","author":"Watt","year":"2003","journal-title":"J Psychopathol Behav Assess"},{"key":"10.1002\/da.20840-BIB57|cit59","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0887-6185(02)00202-5","article-title":"Developmental antecedents of anxiety sensitivity","volume":"17","author":"Scher","year":"2003","journal-title":"J Anxiety Disord"},{"key":"10.1002\/da.20840-BIB58|cit60","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1126\/science.1083968","article-title":"Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene","volume":"301","author":"Caspi","year":"2003","journal-title":"Science"},{"key":"10.1002\/da.20840-BIB59|cit61","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1176\/appi.ajp.2010.09101452","article-title":"Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits","volume":"167","author":"Caspi","year":"2010","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB60|cit62","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1001\/jama.2009.878","article-title":"Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis","volume":"301","author":"Risch","year":"2009","journal-title":"J Am Med Assoc"},{"key":"10.1002\/da.20840-BIB61|cit63","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neulet.2010.08.042","article-title":"Panic disorder and serotonergic genes (SLC6A4, HTR1A and HTR2A): association and interaction with childhood trauma and parenting","volume":"485","author":"Blaya","year":"2010","journal-title":"Neurosci Lett"},{"key":"10.1002\/da.20840-BIB62|cit64","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1601-183X.2010.00593.x","article-title":"Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression","volume":"9","author":"Antypa","year":"2010","journal-title":"Genes Brain Behav"},{"key":"10.1002\/da.20840-BIB63|cit65","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/sj.npp.1301422","article-title":"Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders","volume":"33","author":"Stein","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1002\/da.20840-BIB64|cit66","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1097\/PSY.0b013e318157ad42","article-title":"Serotonin transporter gene polymorphism (5-HTTLPR) and anxiety reactivity in daily life: a daily process approach to gene-environment interaction","volume":"69","author":"Gunthert","year":"2007","journal-title":"Psychosom Med"},{"key":"10.1002\/da.20840-BIB65|cit67","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1017\/S1461145708009875","article-title":"Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults","volume":"12","author":"Laucht","year":"2009","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1002\/da.20840-BIB66|cit68","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1176\/appi.ajp.2009.08101542","article-title":"Serotonin transporter gene (SLC6A4) promoter polymorphisms and the susceptibility to posttraumatic stress disorder in the general population","volume":"166","author":"Grabe","year":"2009","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB67|cit69","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/00004583-200002000-00021","article-title":"Predictors of panic attacks in adolescents","volume":"39","author":"Hayward","year":"2000","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1002\/da.20840-BIB68|cit70","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/S0006-3223(02)01475-0","article-title":"Anxiety sensitivity and panic disorder","volume":"52","author":"McNally","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20840-BIB69|cit71","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: the Edinburgh inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"10.1002\/da.20840-BIB70|cit72","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0924-9338(97)83296-8","article-title":"The Mini International Neuropsychiatric Interview (M.I.N.I.), a short diagnostic interview: reliability and validity according to the CIDI","volume":"12","author":"Lecrubier","year":"1997","journal-title":"Eur Psychiatry"},{"key":"10.1002\/da.20840-BIB71|cit73","volume-title":"Angstsensitivit\u00e4ts-Index","author":"Alpers","year":"2001"},{"key":"10.1002\/da.20840-BIB72|cit74","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1037\/0021-843X.105.3.474","article-title":"Anxiety sensitivity and depression: how are they related?","volume":"105","author":"Taylor","year":"1996","journal-title":"J Abnorm Psychol"},{"key":"10.1002\/da.20840-BIB73|cit75","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1037\/1040-3590.9.3.277","article-title":"Hierarchical structure and general factor saturation of the Anxiety Sensitivity Index: evidence and implications","volume":"9","author":"Zinbarg","year":"1997","journal-title":"Psychol Assess"},{"key":"10.1002\/da.20840-BIB74|cit76","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/0005-7967(96)00006-X","article-title":"Anxiety sensitivity: confirmatory evidence for a multidimensional construct","volume":"34","author":"Cox","year":"1996","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20840-BIB75|cit77","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0887-6185(89)90026-1","article-title":"Anxiety sensitivity: unitary personality trait or domain-specific appraisals?","volume":"3","author":"Telch","year":"1989","journal-title":"J Anxiety Disord"},{"key":"10.1002\/da.20840-BIB76|cit78","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1177\/1073191106295053","article-title":"Sixteen-item Anxiety Sensitivity Index: confirmatory factor analytic evidence, internal consistency, and construct validity in a young adult sample from the Netherlands","volume":"14","author":"Vujanovic","year":"2007","journal-title":"Assessment"},{"key":"10.1002\/da.20840-BIB77|cit79","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0887-6185(90)90029-9","article-title":"Anxiety sensitivity in agoraphobia","volume":"4","author":"Wardle","year":"1990","journal-title":"J Anxiety Disord"},{"key":"10.1002\/da.20840-BIB78|cit80","volume-title":"Childhood Trauma Questionnaire: A Retrospective Self-report Manual","author":"Bernstein","year":"1998"},{"key":"10.1002\/da.20840-BIB79|cit81","unstructured":"Gast U Rodewald F Benecke HH Driessen M Deutsche Bearbeitung des Childhood Traum Questionnaire (unautorisiert)"},{"key":"10.1002\/da.20840-BIB80|cit82","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1055\/s-0030-1247564","article-title":"[The German version of the Childhood Trauma Questionnaire (CTQ): preliminary psychometric properties]","volume":"60","author":"Wingenfeld","year":"2010","journal-title":"Psychother Psychosom Med Psychol"},{"key":"10.1002\/da.20840-BIB81|cit83","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1176\/ajp.151.8.1132","article-title":"Initial reliability and validity of a new retrospective measure of child abuse and neglect","volume":"151","author":"Bernstein","year":"1994","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB82|cit84","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1023\/A:1013058625719","article-title":"The childhood trauma questionnaire in a community sample: psychometric properties and normative data","volume":"14","author":"Scher","year":"2001","journal-title":"J Trauma Stress"},{"key":"10.1002\/da.20840-BIB83|cit85","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/sj.mp.4001789","article-title":"Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531","volume":"11","author":"Wendland","year":"2006","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB84|cit86","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1002\/da.20433","article-title":"Serotonin transporter polymorphism (5-HTTLPR) association with melancholic depression: a female specific effect?","volume":"25","author":"Baune","year":"2008","journal-title":"Depress Anxiety"},{"key":"10.1002\/da.20840-BIB85|cit87","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/mpr.170","article-title":"Centring in regression analyses: a strategy to prevent errors in statistical inference","volume":"13","author":"Kraemer","year":"2004","journal-title":"Int J Methods Psychiatr Res"},{"key":"10.1002\/da.20840-BIB86|cit88","doi-asserted-by":"crossref","DOI":"10.1002\/9781118619179","volume-title":"Structural Equations with Latent Variables","author":"Bollen","year":"1989"},{"key":"10.1002\/da.20840-BIB87|cit89","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1207\/S15328007SEM1004_4","article-title":"The best of both worlds: factor analysis of dichotomous data using item respronse theory and structural equation modeling","volume":"10","author":"Gl\u00f6ckner-Rist","year":"2003","journal-title":"Struct Equ Modeling"},{"key":"10.1002\/da.20840-BIB88|cit90","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2333\/bhmk.29.81","article-title":"Beyond SEM: general latent variable modeling","volume":"29","author":"Muth\u00e9n","year":"2002","journal-title":"Behaviormetrika"},{"key":"10.1002\/da.20840-BIB89|cit91","volume-title":"Mplus User's Guide","author":"Muth\u00e9n","year":"2007"},{"key":"10.1002\/da.20840-BIB90|cit92","article-title":"The power of outliers (and why researchers should always check for them)","volume":"9","author":"Osborne","year":"2004","journal-title":"PARE"},{"key":"10.1002\/da.20840-BIB91|cit93","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0887-6185(87)90002-8","article-title":"The Anxiety Sensitivity Index: construct validity and factor analytic structure","volume":"1","author":"Peterson","year":"1987","journal-title":"J Anxiety Disord"},{"key":"10.1002\/da.20840-BIB92|cit94","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0005-7967(94)00063-P","article-title":"Anxiety sensitivity: theoretical perspectives and recent findings","volume":"33","author":"Taylor","year":"1995","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20840-BIB93|cit95","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/0269881110372543","article-title":"Genetic moderation of CO2- induced fear by 5-HTTPLPR genotype","volume":"25","author":"Schruers","year":"2011","journal-title":"J Psychopharmacol"},{"key":"10.1002\/da.20840-BIB94|cit96","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1017\/S1461145705005869","article-title":"Association of the functional -1019C\/G 5-HT1A polymorphism with prefrontal cortex and amygdala activation measured with 3T fMRI in panic disorder","volume":"9","author":"Domschke","year":"2006","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1002\/da.20840-BIB95|cit97","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00041444-200010040-00002","article-title":"Gender differences in association between serotonin transporter gene polymorphism and personality traits","volume":"10","author":"Du","year":"2000","journal-title":"Psychiatr Genet"},{"key":"10.1002\/da.20840-BIB96|cit98","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1176\/ajp.155.10.1332","article-title":"Serotonin transporter protein gene polymorphism and personality measures in African American and European American subjects","volume":"155","author":"Gelernter","year":"1998","journal-title":"Am J Psychiatry"},{"key":"10.1002\/da.20840-BIB97|cit99","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jpsychores.2005.06.068","article-title":"Gender difference in association between polymorphism of serotonin transporter gene regulatory region and anxiety","volume":"60","author":"Mizuno","year":"2006","journal-title":"J Psychosom Res"},{"key":"10.1002\/da.20840-BIB98|cit100","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.jpsychires.2005.10.002","article-title":"Anxiety- and novelty seeking-related personality traits and serotonin transporter gene polymorphisms","volume":"40","author":"Vormfelde","year":"2006","journal-title":"J Psychiatr Res"},{"key":"10.1002\/da.20840-BIB99|cit101","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.schres.2009.03.021","article-title":"The serotonin transporter gene and disease modification in psychosis: evidence for systematic differences in allelic directionality at the 5-HTTLPR locus","volume":"111","author":"Goldberg","year":"2009","journal-title":"Schizophr Res"},{"key":"10.1002\/da.20840-BIB100|cit102","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1023\/A:1020795114296","article-title":"Prospective Evaluation of Perceived Control, Predictability, and Anxiety Sensitivity in the Pathogenesis of Panic","volume":"24","author":"Schmidt","year":"2002","journal-title":"J Psychopathol Behav Assess"},{"key":"10.1002\/da.20840-BIB101|cit103","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1037\/0022-006X.56.3.405","article-title":"Coping with stressful events in older children and young adolescents","volume":"56","author":"Compas","year":"1988","journal-title":"J Consult Clin Psychol"},{"key":"10.1002\/da.20840-BIB102|cit104","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1111\/1467-8624.00238","article-title":"Appraisal, social support, and life events: predicting outcome behavior in school-age children","volume":"71","author":"Jackson","year":"2000","journal-title":"Child Development"},{"key":"10.1002\/da.20840-BIB103|cit105","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1016\/S0006-3223(99)00262-0","article-title":"A developmental psychopathology model of childhood traumatic stress and intersection with anxiety disorders","volume":"46","author":"Pynoos","year":"1999","journal-title":"Biol Psychiatry"},{"key":"10.1002\/da.20840-BIB104|cit106","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/0005-7967(86)90011-2","article-title":"A cognitive approach to panic","volume":"24","author":"Clark","year":"1986","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20840-BIB105|cit107","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1016\/j.brat.2006.09.017","article-title":"Anxiety sensitivity within the anxiety disorders: disorder-specific sensitivities and depression comorbidity","volume":"45","author":"Rector","year":"2007","journal-title":"Behav Res Ther"},{"key":"10.1002\/da.20840-BIB106|cit108","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1017\/S0033291706009640","article-title":"Generalized anxiety disorder and depression: childhood risk factors in a birth cohort followed to age 32","volume":"37","author":"Moffitt","year":"2007","journal-title":"Psychol Med"},{"key":"10.1002\/da.20840-BIB107|cit109","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10802-005-0930-3","article-title":"Early adversity and the prospective prediction of depressive and anxiety disorders in adolescents","volume":"33","author":"Phillips","year":"2005","journal-title":"J Abnorm Child Psychol"},{"key":"10.1002\/da.20840-BIB108|cit110","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1037\/a0019552","article-title":"Respiratory and cognitive mediators of treatment change in panic disorder: evidence for intervention specificity","volume":"78","author":"Meuret","year":"2010","journal-title":"J Consult Clin Psychol"},{"key":"10.1002\/da.20840-BIB109|cit111","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1001\/archpsyc.62.9.953","article-title":"The current state of cognitive therapy: a 40-year retrospective","volume":"62","author":"Beck","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"10.1002\/da.20840-BIB110|cit112","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.cpr.2005.07.003","article-title":"The empirical status of cognitive-behavioral therapy: a review of meta-analyses","volume":"26","author":"Butler","year":"2006","journal-title":"Clin Psychol Rev"},{"key":"10.1002\/da.20840-BIB111|cit113","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.cpr.2010.01.003","article-title":"A systematic review of behavioral experiments vs. exposure alone in the treatment of anxiety disorders: a case of exposure while wearing the emperor's new clothes?","volume":"30","author":"McMillan","year":"2010","journal-title":"Clin Psychol Rev"},{"key":"10.1002\/da.20840-BIB112|cit114","first-page":"30","article-title":"Psychotherapeutic approaches to the treatment of anxiety and depressive disorders","volume":"58","author":"Michels","year":"1997","journal-title":"J Clin Psychiatry"},{"key":"10.1002\/da.20840-BIB113|cit115","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1037\/1040-3590.6.2.92","article-title":"On the \u201cremembrance of things past\u201d: a longitudinal evaluation of the retrospective method","volume":"6","author":"Henry","year":"1994","journal-title":"Psychol Assess"},{"key":"10.1002\/da.20840-BIB114|cit116","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/sj.mp.4001627","article-title":"Does measurement instrument moderate the association between the serotonin transporter gene and anxiety-related personality traits? A meta-analysis","volume":"10","author":"Munafo","year":"2005","journal-title":"Mol Psychiatry"},{"key":"10.1002\/da.20840-BIB115|cit117","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/mp.2009.123","article-title":"The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update","volume":"15","author":"Uher","year":"2010","journal-title":"Mol Psychiatry"}],"container-title":["Depression and Anxiety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fda.20840","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/da.20840","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,7]],"date-time":"2024-04-07T18:03:32Z","timestamp":1712513012000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/da.20840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,16]]},"references-count":115,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"URL":"https:\/\/doi.org\/10.1002\/da.20840","relation":{},"ISSN":["1091-4269"],"issn-type":[{"value":"1091-4269","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6,16]]}}}