{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:21:53Z","timestamp":1792606913925,"version":"4.5.0"},"reference-count":44,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T00:00:00Z","timestamp":1503014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T00:00:00Z","timestamp":1503014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000155","name":"Social Sciences and Humanities Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000155","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Quebec Fund for Research on Nature and Technology"},{"name":"Quebec Fund for Research on Society and Culture"},{"name":"Health Research Fund of Quebec"},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Health and Social Services"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Depress Anxiety"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1002\/da.22674","type":"journal-article","created":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T15:22:42Z","timestamp":1503069762000},"page":"918-927","source":"Crossref","is-referenced-by-count":38,"title":["Early childhood trajectories of separation anxiety: Bearing on mental health, academic achievement, and physical health from mid-childhood to preadolescence"],"prefix":"10.1155","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0864-894X","authenticated-orcid":false,"given":"Marco","family":"Battaglia","sequence":"first","affiliation":[{"name":"Department of Psychiatry; University of Toronto; Toronto ON Canada"},{"name":"Division of Child Youth and Emerging Adult Psychiatry; Centre for Addiction and Mental Health; Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Garon-Carrier","sequence":"additional","affiliation":[{"name":"GRIP; School of Psychology; Universit\u00e9 Laval; Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvana M.","family":"C\u00f4t\u00e9","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Psychology; Universit\u00e9 de Montr\u00e9al; Montr\u00e9al Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ginette","family":"Dionne","sequence":"additional","affiliation":[{"name":"GRIP; School of Psychology; Universit\u00e9 Laval; Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyne","family":"Touchette","sequence":"additional","affiliation":[{"name":"Department of Psychoeducation; Universit\u00e9 du Qu\u00e9bec \u00e0 Trois-Rivi\u00e8res; Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Vitaro","sequence":"additional","affiliation":[{"name":"Department of Psychoeducation; Universit\u00e9 de Montr\u00e9al; Montr\u00e9al Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Tremblay","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Psychology; Universit\u00e9 de Montr\u00e9al; Montr\u00e9al Canada"},{"name":"School of Public Health; Physiotherapy and Population Sciences; University College Dublin; Dublin Ireland"},{"name":"Institute of Genetic; Neurobiological; and Social Foundations of Child Development; Tomsk State University; Tomsk Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Boivin","sequence":"additional","affiliation":[{"name":"GRIP; School of Psychology; Universit\u00e9 Laval; Qu\u00e9bec Canada"},{"name":"Institute of Genetic; Neurobiological; and Social Foundations of Child Development; Tomsk State University; Tomsk Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,18]]},"reference":[{"key":"10.1002\/da.22674-BIB0001|da22674-cit-0001","volume-title":"Child behavior checklist","author":"Achenbach","year":"1991"},{"key":"10.1002\/da.22674-BIB0002|da22674-cit-0002","doi-asserted-by":"crossref","first-page":"183","DOI":"10.31887\/DCNS.2015.17.3\/mbattaglia","article-title":"Separation anxiety at the neurobiological crossroads of adaptation and illness","volume":"17","author":"Battaglia","year":"2015","journal-title":"Dialogues in Clinical Neuroscience"},{"key":"10.1002\/da.22674-BIB0003|da22674-cit-0003","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1176\/ajp.155.5.590","article-title":"Anticipation of age at onset in panic disorder","volume":"155","author":"Battaglia","year":"1998","journal-title":"American Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0004|da22674-cit-0004","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1176\/ajp.152.9.1362","article-title":"Age at onset of panic disorder: Influence of familial liability to the disease and of childhood separation anxiety disorder","volume":"152","author":"Battaglia","year":"1995","journal-title":"American Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0005|da22674-cit-0005","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/jcpp.12424","article-title":"Distinct trajectories of separation anxiety in the preschool years: Persistence at school entry and early-life associated factors","volume":"57","author":"Battaglia","year":"2016","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"10.1002\/da.22674-BIB0006|da22674-cit-0006","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1037\/h0037058","article-title":"A behavior rating scale for the preschool child","volume":"10","author":"Behar","year":"1974","journal-title":"Developmental Psychology"},{"key":"10.1002\/da.22674-BIB0007|da22674-cit-0007","first-page":"217","volume-title":"Handbook of child behavior therapy in the psychiatric setting","author":"Bell-Dolan","year":"1995"},{"key":"10.1002\/da.22674-BIB0008|da22674-cit-0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1129-2377-14-79","article-title":"Headache and comorbidity in children and adolescents","volume":"14","author":"Bellini","year":"2013","journal-title":"Journal of Headache and Pain"},{"key":"10.1002\/da.22674-BIB0009|da22674-cit-0009","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.cpr.2013.03.006","article-title":"Adult separation anxiety disorder in DSM-5","volume":"33","author":"B\u00f6gels","year":"2013","journal-title":"Clinical Psychology Review"},{"key":"10.1002\/da.22674-BIB0010|da22674-cit-0010","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1177\/070674379303800605","article-title":"Evaluation of the original Ontario Child Health Study scales","volume":"38","author":"Boyle","year":"1993","journal-title":"Canadian Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0011|da22674-cit-0011","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.cpr.2005.12.002","article-title":"Anxiety in a neglected population: Prevalence of anxiety disorders in pre-adolescent children","volume":"26","author":"Cartwright-Hatton","year":"2006","journal-title":"Clinical Psychology Review"},{"key":"10.1002\/da.22674-BIB0012|da22674-cit-0012","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jaac.2013.09.017","article-title":"Longitudinal patterns of anxiety from childhood to adulthood: The Great Smoky Mountains Study","volume":"53","author":"Copeland","year":"2014","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"10.1002\/da.22674-BIB0013|da22674-cit-0013","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1001\/archgenpsychiatry.2009.85","article-title":"Childhood and adolescent psychiatric disorders as predictors of young adult disorders","volume":"66","author":"Copeland","year":"2009","journal-title":"Archives of General Psychiatry"},{"key":"10.1002\/da.22674-BIB0014|da22674-cit-0014","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/j.1469-7610.2011.02446.x","article-title":"Trends in psychopathology across the adolescent years: What changes when children become adolescents, and when adolescents become adults","volume":"52","author":"Costello","year":"2011","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"10.1002\/da.22674-BIB0015|da22674-cit-0015","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1097\/01.chi.0000172552.41596.6f","article-title":"10-year research update review: The epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burden","volume":"44","author":"Costello","year":"2005","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"10.1002\/da.22674-BIB0016|da22674-cit-0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep25131","article-title":"Histone modifications in a mouse model of early adversities and panic disorder: Role for Asic1 and neurodevelopmental genes","volume":"6","author":"Cittaro","year":"2016","journal-title":"Scientific Reports"},{"key":"10.1002\/da.22674-BIB0017|da22674-cit-0017","doi-asserted-by":"crossref","first-page":"e18637","DOI":"10.1371\/journal.pone.0018637","article-title":"Unstable maternal environment, separation anxiety and heightened CO2 sensitivity induced by gene-by-environment interplay","volume":"6","author":"D'Amato","year":"2011","journal-title":"PLoS One"},{"key":"10.1002\/da.22674-BIB0018|da22674-cit-0018","first-page":"475","volume-title":"Textbook of anxiety disorders","author":"DuPont","year":"2002"},{"key":"10.1002\/da.22674-BIB0019|da22674-cit-0019","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1469-7610.2009.02138.x","article-title":"Do family mealtime interactions mediate the association between asthma symptoms and separation anxiety","volume":"51","author":"Fiese","year":"2010","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"10.1002\/da.22674-BIB0020|da22674-cit-0020","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.jaac.2013.09.008","article-title":"Preschool anxiety disorders in pediatric primary care: Prevalence and comorbidity","volume":"52","author":"Franz","year":"2013","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"10.1002\/da.22674-BIB0021|da22674-cit-0021","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1468-2982.2006.01271.x","article-title":"Headache and recurrent abdominal pain: A controlled study by the means of the Child Behaviour Checklist (CBCL)","volume":"27","author":"Galli","year":"2007","journal-title":"Cephalalgia"},{"key":"10.1002\/da.22674-BIB0022|da22674-cit-0022","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1001\/jamapsychiatry.2013.4186","article-title":"Naturalistic follow-up of youths treated for pediatric anxiety disorders","volume":"71","author":"Ginsburg","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"10.1002\/da.22674-BIB0023|da22674-cit-0023","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jad.2012.08.034","article-title":"Baseline respiratory parameters in panic disorder: A meta-analysis","volume":"146","author":"Grassi","year":"2013","journal-title":"Journal of Affective Disorders"},{"key":"10.1002\/da.22674-BIB0024|da22674-cit-0024","first-page":"1","volume-title":"Longitudinal study of child development in Quebec (ELDEQ 1998-2002)","volume":"1","author":"Jett\u00e9","year":"2000"},{"key":"10.1002\/da.22674-BIB0025|da22674-cit-0025","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","article-title":"Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Archives of General Psychiatry"},{"key":"10.1002\/da.22674-BIB0026|da22674-cit-0026","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1176\/appi.ajp.2012.12070893","article-title":"The separation anxiety hypothesis of panic disorder revisited: A meta-analysis","volume":"170","author":"Kossowsky","year":"2013","journal-title":"American Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0027|da22674-cit-0027","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1192\/bjp.bp.108.052159","article-title":"Association of headache with childhood adversity and mental disorder: Cross-national study","volume":"194","author":"Lee","year":"2009","journal-title":"British Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0028|da22674-cit-0028","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1176\/appi.ajp.2013.13060781","article-title":"Childhood separation anxiety and the pathogenesis and treatment of adult anxiety","volume":"171","author":"Milrod","year":"2014","journal-title":"American Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0029|da22674-cit-0029","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1542\/peds.2009-0701","article-title":"Poverty and chronic illness in early childhood: A comparison between the United kingdom and Quebec","volume":"125","author":"Niki\u00e9ma","year":"2010","journal-title":"Pediatrics"},{"key":"10.1002\/da.22674-BIB0030|da22674-cit-0030","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1001\/archpsyc.57.10.960","article-title":"Differential carbon dioxide sensitivity in childhood anxiety disorders and nonill comparison group","volume":"57","author":"Pine","year":"2000","journal-title":"Archives of General Psychiatry"},{"key":"10.1002\/da.22674-BIB0031|da22674-cit-0031","doi-asserted-by":"crossref","first-page":"e0166089","DOI":"10.1371\/journal.pone.0166089","article-title":"Acid-sensing ion channel 1a contributes to airway hyperreactivity in mice","volume":"11","author":"Reznikov","year":"2016","journal-title":"PLoS One"},{"key":"10.1002\/da.22674-BIB0032|da22674-cit-0032","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/da.21931","article-title":"Childhood separation anxiety disorder and adult onset panic attacks share a common genetic diathesis","volume":"29","author":"Roberson-Nay","year":"2012","journal-title":"Depression and Anxiety"},{"key":"10.1002\/da.22674-BIB0033|da22674-cit-0033","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.biopsych.2009.12.014","article-title":"Carbon dioxide hypersensitivity in separation-anxious offspring of parents with panic disorder","volume":"67","author":"Roberson-Nay","year":"2010","journal-title":"Biological Psychiatry"},{"key":"10.1002\/da.22674-BIB0034|da22674-cit-0034","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1002\/da.21941","article-title":"Genetic and environmental contributions to separation anxiety disorder: A meta-analytic approach to twin data","volume":"29","author":"Scaini","year":"2012","journal-title":"Depression and Anxiety"},{"key":"10.1002\/da.22674-BIB0035|da22674-cit-0035","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1176\/ajp.2006.163.6.1074","article-title":"Prevalence and correlates of estimated DSM-IV child and adult separation anxiety disorder in the National Comorbidity Survey Replication","volume":"163","author":"Shear","year":"2006","journal-title":"American Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0036|da22674-cit-0036","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1001\/jama.2009.754","article-title":"Neuroscience, molecular biology, and the childhood roots of health disparities: Building a new framework for health promotion and disease prevention","volume":"301","author":"Shonkoff","year":"2009","journal-title":"JAMA"},{"key":"10.1002\/da.22674-BIB0037|da22674-cit-0037","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1176\/appi.ajp.2015.14091185","article-title":"Pediatric-onset and adult-onset separation anxiety disorder across countries in the World Mental Health Survey","volume":"172","author":"Silove","year":"2015","journal-title":"American Journal of Psychiatry"},{"key":"10.1002\/da.22674-BIB0038|da22674-cit-0038","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/jcpp.12506","article-title":"Editorial: Distinguishing between the challenges posed by surface and deep forms of heterogeneity to diagnostic systems: Do we need a new approach to subtyping of child and adolescent psychiatric disorders","volume":"57","author":"Sonuga-Barke","year":"2016","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"10.1002\/da.22674-BIB0039|da22674-cit-0039","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/ajmg.b.31144","article-title":"Gene-environment interactions in panic disorder and CO2 sensitivity: Effects of events occurring early in life","volume":"156","author":"Spatola","year":"2011","journal-title":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics"},{"key":"10.1002\/da.22674-BIB0040|da22674-cit-0040","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1207\/s15374424jccp2201_11","article-title":"Agreement among parents, teachers, and children on internalizing and externalizing behavior problems","volume":"22","author":"Stanger","year":"1993","journal-title":"Journal of Clinical Child Psychology"},{"key":"10.1002\/da.22674-BIB0041|da22674-cit-0041","unstructured":"Sylvester , C. M. Pine , D. 2016 Anxiety disorders Joan L. Luby (Ed.) Handbook of preschool mental health: Development, disorders, and treatment New York, NY Guilford"},{"key":"10.1002\/da.22674-BIB0042|da22674-cit-0042","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF00911232","article-title":"Disruptive boys with stable and unstable high fighting behavior patterns during junior elementary school","volume":"19","author":"Tremblay","year":"1991","journal-title":"Journal of Abnormal Child Psychology"},{"key":"10.1002\/da.22674-BIB0043|da22674-cit-0043","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.neuroimage.2009.06.015","article-title":"Dyspnea and pain share emotion-related brain network","volume":"48","author":"Leupoldt","year":"2009","journal-title":"NeuroImage"},{"key":"10.1002\/da.22674-BIB0044|da22674-cit-0044","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nrn3529","article-title":"Acid-sensing ion channels in pain and disease","volume":"14","author":"Wemmie","year":"2013","journal-title":"Nature Reviews Neuroscience"}],"container-title":["Depression and Anxiety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fda.22674","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/da.22674\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:04:48Z","timestamp":1671541488000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/da.22674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,18]]},"references-count":44,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"URL":"https:\/\/doi.org\/10.1002\/da.22674","archive":["Portico"],"relation":{},"ISSN":["1091-4269"],"issn-type":[{"value":"1091-4269","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8,18]]}}}