{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T06:01:34Z","timestamp":1780639294753,"version":"3.54.1"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"vor","delay-in-days":75,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alz &amp; Dem Diag Ass &amp; Dis Mo"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The approval of a disease\u2010modifying Alzheimer's disease (AD) treatment could provide relief to US state budgets that were hit hard by the COVID\u201019 pandemic, as mostly Medicare would cover treatment cost, whereas Medicaid would see savings from reduced nursing home use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We project savings from 2021 to 2040 with a simulation model from the perspective of state Medicaid programs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Assuming a 40% and 22% relative reduction of disease progression rates with treatment, Medicaid would avoid payments of $186.2 and $93.5 billion for around 1.11 and 0.57 million nursing home patient\u2010years, respectively. The savings correspond to a 5.06% and 2.49%, respectively, relative reduction of Medicaid spending on nursing home care. Higher per capita savings were projected for older states, those with higher Medicaid payment rates, those with more nursing home residents covered by Medicaid, and those with a lower federal contribution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>States stand to realize substantial savings from a potential AD treatment. A state's health system preparedness to handle the large number of patients will influence the actual magnitude of the savings and how fast they will accrue.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dad2.12159","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T08:54:31Z","timestamp":1615971271000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Projection of budgetary savings to US state Medicaid programs from reduced nursing home use due to an Alzheimer's disease treatment"],"prefix":"10.1002","volume":"13","author":[{"given":"Jenny","family":"Lam","sequence":"first","affiliation":[{"name":"University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hankyung","family":"Jun","sequence":"additional","affiliation":[{"name":"University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Kyu","family":"Cho","sequence":"additional","affiliation":[{"name":"University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Hanson","sequence":"additional","affiliation":[{"name":"University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soeren","family":"Mattke","sequence":"additional","affiliation":[{"name":"University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"NPR Staff.States Are Broke And Many Are Eyeing Massive Cuts. Here's How Yours Is Doing. COVID\u201019 Throws States Into Budget Crises 2020;https:\/\/www.npr.org\/2020\/08\/03\/893190275\/states-are-broke-and-many-are-eyeing-massive-cuts-heres-how-yours-is-doing. Accessed August 8 2020."},{"key":"e_1_2_9_3_1","unstructured":"National Association of State Budget Officers.Summaries of Fiscal Year 2021 Proposed Budgets.2020. Issue Brief April 28 2020 available athttps:\/\/www.nasbo.org\/resources\/proposed-enacted-budgets. Accessed February 12 2021."},{"key":"e_1_2_9_4_1","volume-title":"Stress\u2010Testing States: COVID\u201019","author":"White D","year":"2020"},{"key":"e_1_2_9_5_1","unstructured":"WalczakJ CammengaJ.State Rainy Day Funds and the COVID\u201019 Crisis.2020. Available athttps:\/\/taxfoundation.org\/state-rainy-day-funds-covid-19\/ Accesssed February 12 2021."},{"key":"e_1_2_9_6_1","unstructured":"McNicholE LeachmanM.States Continue to Face Large Shortfalls Due to COVID\u201019 Effects.2020. 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Available athttps:\/\/www.cms.gov\/files\/document\/2018-report.pdf Accessed February 12 2021."},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/475S1a"},{"key":"e_1_2_9_15_1","volume-title":"Medicaid Expenditures for Long\u2010Term Services and Supports in FY 2016","author":"Eiken S","year":"2018"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.26419\/ppi.00079.001"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.2000"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.7249\/RR2272"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/dad2.12081"},{"key":"e_1_2_9_20_1","unstructured":"CensusU.Annual Estimates of the Civilian Population by Single Year of Age and Sex for the United States and States: April 1 2010 to July 1 2018.2020;https:\/\/www.census.gov\/data\/tables\/time\u2010series\/demo\/popest\/2010s\u2010state\u2010detail.html. 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